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Cited by 553

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Epigenetic reprogramming and induced pluripotency

Open access
Hochedlinger, Konrad, Plath, Kathrin·2009·Development

Abstract

The cloning of animals from adult cells has demonstrated that the developmental state of adult cells can be reprogrammed into that of embryonic cells by uncharacterized factors within the oocyte. More recently,transcription factors have been identified that can induce pluripotency in somatic cells without the use of oocytes, generating induced pluripotent stem(iPS) cells. iPS cells provide a unique platform to dissect the molecular mechanisms that underlie epigenetic reprogramming. Moreover, iPS cells can teach us about principles of normal development and disease, and might ultimately facilitate the treatment of patients by custom-tailored cell therapy.

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Crossref · 10.1242/dev.020867

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Metadata

Authors
Hochedlinger, K., & Plath, K.
Venue
Development
Published
2009-02-15
Volume
136
Issue
4
Pages
509-523
ISSN
  • 0950-1991 (ISSN-L)
  • 1477-9129
OpenAlex
W1965698498
Cited by
553
References
13
FWCI
33.49
Type
journal article
Language
en
Open access
bronze

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.