The DOI matches its Crossref record.
Microtubules mediate the localization of bicoid RNA during Drosophila oogenesis
Abstract
We have examined cytoskeletal requirements for bicoid (bed) RNA localization during Drosophila oogenesis, bed is an anterior morphogen whose proper function relies on the localization of its messenger RNA to the anterior cortex of the egg. Drugs that depolymerize microtubules perturb all aspects of bed RNA localization. During recovery from drug treatment, bed RNA relocalizes to the oocyte cortex, suggesting that the localization machinery is a component of the cortical cytoskeleton. Taxol, a drug that stabilizes microtubules, also effectively disrupts bed RNA localization, and the effects of taxol treatments on exuperantia and swallow mutants suggest general roles for these gene products in the multi-step bed RNA localization process.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Theurkauf, W. E., Smiley, S., Wong, M. L., & Alberts, B. M. (1992) · Development · doi:10.1242/dev.115.4.923 · Cited by 396
RNA LOCALIZATION IN DEVELOPMENT
Bashirullah, A., Cooperstock, R. L., & Lipshitz, H. D. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.335 · Cited by 339
Micklem, D. R., Dasgupta, R., Elliott, H., Gergely, F., Davidson, C., Brand, A., González-Reyes, A., & St Johnston, D. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00218-1 · Cited by 189
Metadata
- Authors
- Pokrywka, N. J., & Stephenson, E. C.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1991-09-01
- Volume
- 113
- Issue
- 1
- Pages
- 55-66
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2216863369
- Cited by
- 250
- References
- 0
- FWCI
- 7.36
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
