The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
Pax-6, a murine paired box gene, is expressed in the developing CNS
Abstract
A multigene family of paired-box-containing genes (Pax genes) has been identified in the mouse. In this report, we describe the expression pattern of Pax-6 during embryogenesis and the isolation of cDNA clones spanning the entire coding region. The Pax-6 protein consists of 422 amino acids as deduced from the longest open reading frame and contains, in addition to the paired domain, a paired-type homeodomain. Beginning with day 8 of gestation, Pax-6 is expressed in discrete regions of the forebrain and the hindbrain. In the neural tube, expression is mainly confined to mitotic active cells in the ventral ventricular zone along the entire anteroposterior axis starting at day 8.5 of development. Pax-6 is also expressed in the developing eye, the pituitary and the nasal epithelium.
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Altered Neural Cell Fates and Medulloblastoma in Mouse patched Mutants
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Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila
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Homology of the eyeless Gene of Drosophila to the Small eye Gene in Mice and Aniridia in Humans
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Molecular logic of neocortical projection neuron specification, development and diversity
Greig, L. C., Woodworth, M. B., Galazo, M. J., Padmanabhan, H., & Macklis, J. D. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3586 · Cited by 863
Glial cells generate neurons: the role of the transcription factor Pax6
Heins, N., Malatesta, P., Cecconi, F., Nakafuku, M., Tucker, K. L., Hack, M. A., Chapouton, P., Barde, Y.-A., & Götz, M. (2002) · Nature Neuroscience · doi:10.1038/nn828 · Cited by 775
Metadata
- Authors
- Walther, C., & Gruss, P.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1991-12-01
- Volume
- 113
- Issue
- 4
- Pages
- 1435-1449
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2161687343
- Cited by
- 1,255
- References
- 57
- FWCI
- 12.56
- Type
- journal article
- Language
- en
- Open access
- closed
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- Walther, C., & Gruss, P. (1991). Pax-6, a murine paired box gene, is expressed in the developing CNS. Development. https://doi.org/10.1242/dev.113.4.1435
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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