The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis
Abstract
We have identified a novel frog gene, Pintallavis (the Catalan for lipstick), that is related to the fly fork head and rat HNF-3 genes. Pintallavis is expressed in the organizer region of gastrula embryos as a direct zygotic response to dorsal mesodermal induction. Subsequently, Pintallavis is expressed in axial midline cells of all three germ layers. In axial mesoderm expression is graded with highest levels posteriorly. Midline neural plate cells that give rise to the floor plate transiently express Pin tallavis, apparently in response to induction by the notochord. Overexpression of Pintallavis perturbs the development of the neural axis, suppressing the differentiation of anterior and dorsal neural cell types but causing an expansion of the posterior neural tube. Our results suggest that Pintallavis functions in the induction and patterning of the neural axis.
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Cites
A major developmental transition in early xenopus embryos: II. control of the onset of transcription
Newport, J., & Kirschner, M. (1982) · Cell · doi:10.1016/0092-8674(82)90273-2 · Cited by 1,055
Cited by
Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation
Heisenberg, C.-P., Tada, M., Rauch, G.-J., Saúde, L., Concha, M. L., Geisler, R., Stemple, D. L., Smith, J. C., & Wilson, S. W. (2000) · Nature · doi:10.1038/35011068 · Cited by 1,013
Roelink, H., Augsburger, A., Heemskerk, J., Korzh, V., Norlin, S., Ruiz i Altaba, A., Tanabe, Y., Placzek, M., Edlund, T., Jessell, T. M., et al. (1994) · Cell · doi:10.1016/0092-8674(94)90514-2 · Cited by 854
Self-citationFORMATION AND FUNCTION OF SPEMANN'S ORGANIZER
Harland, R., & Gerhart, J. (1997) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.13.1.611 · Cited by 839
Requirement for LIml in head-organizer function
Shawlot, W., & Behringer, R. R. (1995) · Nature · doi:10.1038/374425a0 · Cited by 805
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Wallingford, J. B., Rowning, B. A., Vogeli, K. M., Rothbächer, U., Fraser, S. E., & Harland, R. M. (2000) · Nature · doi:10.1038/35011077 · Cited by 751
Metadata
- Authors
- Altaba, A. R. I., & Jessell, T. M.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1992-09-01
- Volume
- 116
- Issue
- 1
- Pages
- 81-93
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W1943352952
- Cited by
- 329
- References
- 1
- FWCI
- 12.22
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis. https://app.cochat.ai/papers/10.1242/dev.116.1.81
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- Altaba, A. R. I., & Jessell, T. M. (1992). Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis. Development. https://doi.org/10.1242/dev.116.1.81
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
