The DOI matches its Crossref record.
Homeobox genes and connective tissue patterning
Open accessAbstract
In vertebrates, limb tendons are derived from cells that migrate from the lateral plate mesoderm during early development. While some of the developmental steps leading to the formation of these tissues are known, little is known about the molecular mechanisms controlling them. We have identified two murine homeobox-containing genes, Six 1 and Six 2, which are expressed in a complementary fashion during the development of limb tendons. Transcripts for both genes are found in different sets of phalangeal tendons. Six 1 and Six 2 also are expressed in skeletal and smooth muscle, respectively. These genes may participate in the patterning of the distal tendons of the limb phalanges by setting positional values along the limb axes.
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Citations
Cited by
Six1 is required for the early organogenesis of mammalian kidney
Xu, P.-X., Zheng, W., Huang, L., Maire, P., Laclef, C., & Silvius, D. (2003) · Development · doi:10.1242/dev.00536 · Cited by 361
Xu, P.-X., Woo, I., Her, H., Beier, D. R., & Maas, R. L. (1997) · Development · doi:10.1242/dev.124.1.219 · Cited by 331
Six3 overexpression initiates the formation of ectopic retina
Loosli, F., Winkler, S., & Wittbrodt, J. (1999) · Genes & Development · doi:10.1101/gad.13.6.649 · Cited by 257
Arendt, D., Tessmar, K., de Campos-Baptista, M.-I. M., Dorresteijn, A., & Wittbrodt, J. (2002) · Development · doi:10.1242/dev.129.5.1143 · Cited by 192
Metadata
- Authors
- Oliver, G., Wehr, R., Jenkins, N. A., Copeland, N. G., Cheyette, B. N. R., Hartenstein, V., Zipursky, S. L., & Gruss, P.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1995-03-01
- Volume
- 121
- Issue
- 3
- Pages
- 693-705
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2109194190
- Cited by
- 328
- References
- 0
- FWCI
- 4.50
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Homeobox genes and connective tissue patterning. https://app.cochat.ai/papers/10.1242/dev.121.3.693
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- Oliver, G., Wehr, R., Jenkins, N. A., Copeland, N. G., Cheyette, B. N. R., Hartenstein, V., Zipursky, S. L., & Gruss, P. (1995). Homeobox genes and connective tissue patterning. Development. https://doi.org/10.1242/dev.121.3.693
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