The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Six3 overexpression initiates the formation of ectopic retina
Open accessAbstract
The homeobox gene sine oculis (so) is essential for visual system formation in Drosophila. A vertebrate member of the so/Six gene family, Six3, is expressed in the developing eye and forebrain. Injection of Six3 RNA into medaka fish embryos causes ectopic Pax6 and Rx2 expression in midbrain and cerebellum, resulting in the formation of ectopic retinal primordia. Injected mouse Six3 RNA initiates ectopic expression of endogenous medaka Six3, uncovering a feedback control of Six3 expression. Initiation of ectopic retina formation reveals a pivotal role for Six3 in vertebrate retina development and hints at a conserved regulatory network underlying vertebrate and invertebrate eye development.
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Cites
Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila
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Stages of normal development in the medaka Oryzias latipes
Iwamatsu, T. (2004) · Mechanisms of Development · doi:10.1016/j.mod.2004.03.012 · Cited by 1,200
Mouse Small eye results from mutations in a paired-like homeobox-containing gene
Hill, R. E., Favor, J., Hogan, B. L. M., Ton, C. C. T., Saunders, G. F., Hanson, I. M., Prosser, J., Jordan, T., Hastie, N. D., & Heyningen, V. V. (1991) · Nature · doi:10.1038/354522a0 · Cited by 1,158
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Ton, C. C. T., Hirvonen, H., Miwa, H., Weil, M. M., Monaghan, P., Jordan, T., van Heyningen, V., Hastie, N. D., Meijers-Heijboer, H., Drechsler, M., et al. (1991) · Cell · doi:10.1016/0092-8674(91)90284-6 · Cited by 862
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The Rx homeobox gene is essential for vertebrate eye development
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Cited by
WNTS in the vertebrate nervous system: from patterning to neuronal connectivity
Ciani, L., & Salinas, P. C. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1665 · Cited by 543
Arendt, D., Tessmar, K., de Campos-Baptista, M.-I. M., Dorresteijn, A., & Wittbrodt, J. (2002) · Development · doi:10.1242/dev.129.5.1143 · Cited by 192
Self-citationMedaka eyeless is the key factor linking retinal determination and eye growth
Loosli, F., Winkler, S., Burgtorf, C., Wurmbach, E., Ansorge, W., Henrich, T., Grabher, C., Arendt, D., Carl, M., Krone, A., et al. (2001) · Development · doi:10.1242/dev.128.20.4035 · Cited by 135
Self-citationYang, X., ZarinKamar, N., Bao, R., & Friedrich, M. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.02.040 · Cited by 51
Metadata
- Authors
- Loosli, F., Winkler, S., & Wittbrodt, J.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1999-03-15
- Volume
- 13
- Issue
- 6
- Pages
- 649-654
- ISSN
- 0890-9369 (ISSN-L)
- OpenAlex
- W2136010410
- Cited by
- 257
- References
- 36
- Type
- posted content
- Language
- en
- Open access
- diamond
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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