The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
SPATULA, a gene that controls development of carpel margin tissues in Arabidopsis, encodes a bHLH protein
Abstract
Studies involving mutants of the gene SPATULA indicate that it promotes the growth of carpel margins and of pollen tract tissues derived from them. We show that it encodes a new member of the basic-helix-loop-helix family of transcription factors. SPATULA is expressed in marginal and pollen tract tissues throughout their development confirming its role in regulating their growth. It is also expressed in many other tissues where it may act redundantly to control growth, including the peripheral zone of the shoot apical meristem, and specific tissues within leaves, petals, stamens and roots. Expression in the stomium, funiculus and valve dehiscence zone indicates an additional role in abscission. SPATULA expression does not require the function of the other carpel development genes CRABS CLAW and AGAMOUS, although its expression is repressed in first whorl organs by the A function gene APETALA2. Further, we have shown that disruptions to gynoecial pattern formation seen in ettin mutants can largely be attributed to ectopic SPATULA action. ETTIN’s role seems to be to negatively regulate SPATULA expression in abaxial regions of the developing gynoecium. SPATULA is the first basic-helix-loop-helix gene in plants known to play a role in floral organogenesis.
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Cites
Early flower development in Arabidopsis.
Smyth, D. R., Bowman, J. L., & Meyerowitz, E. M. (1990) · The Plant Cell · doi:10.1105/tpc.2.8.755 · Cited by 2,155
Self-citationNuclear targeting sequences — a consensus?
Dingwall, C., & Laskey, R. A. (1991) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(91)90184-w · Cited by 1,876
A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis
Long, J. A., Moan, E. I., Medford, J. I., & Barton, M. K. (1996) · Nature · doi:10.1038/379066a0 · Cited by 1,537
LEAFY controls floral meristem identity in Arabidopsis
Weigel, D., Alvarez, J., Smyth, D. R., Yanofsky, M. F., & Meyerowitz, E. M. (1992) · Cell · doi:10.1016/0092-8674(92)90295-n · Cited by 1,505
Self-citationCombining evolutionary information and neural networks to predict protein secondary structure
Rost, B., & Sander, C. (1994) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.340190108 · Cited by 1,452
Genetic interactions among floral homeotic genes of Arabidopsis
Bowman, J. L., Smyth, D. R., & Meyerowitz, E. M. (1991) · Development · doi:10.1242/dev.112.1.1 · Cited by 1,166
Self-citationControl of Arabidopsis flower and seed development by the homeotic gene APETALA2.
Jofuku, K. D., den Boer, B. G., Van Montagu, M., & Okamuro, J. K. (1994) · The Plant Cell · doi:10.1105/tpc.6.9.1211 · Cited by 1,137
Role of arabidopsis MYC and MYB homologs in drought- and abscisic acid-regulated gene expression.
Abe, H., Yamaguchi-Shinozaki, K., Urao, T., Iwasaki, T., Hosokawa, D., & Shinozaki, K. (1997) · The Plant Cell · doi:10.1105/tpc.9.10.1859 · Cited by 1,049
ARF1, a Transcription Factor That Binds to Auxin Response Elements
Ulmasov, T., Hagen, G., & Guilfoyle, T. J. (1997) · Science · doi:10.1126/science.276.5320.1865 · Cited by 973
SHATTERPROOF MADS-box genes control seed dispersal in Arabidopsis
Liljegren, S. J., Ditta, G. S., Eshed, Y., Savidge, B., Bowman, J. L., & Yanofsky, M. F. (2000) · Nature · doi:10.1038/35008089 · Cited by 957
Cited by
Makkena, S., & Lamb, R. S. (2013) · BMC Plant Biology · doi:10.1186/1471-2229-13-1 · Cited by 462
Control of Fruit Patterning in Arabidopsis by INDEHISCENT
Liljegren, S. J., Roeder, A. H. K., Kempin, S. A., Gremski, K., Østergaard, L., Guimil, S., Reyes, D. K., & Yanofsky, M. F. (2004) · Cell · doi:10.1016/s0092-8674(04)00217-x · Cited by 444
Alvarez-Buylla, E. R., Benítez, M., Corvera-Poiré, A., Chaos Cador, Á., de Folter, S., Gamboa de Buen, A., Garay-Arroyo, A., García-Ponce, B., Jaimes-Miranda, F., Pérez-Ruiz, R. V., et al. (2010) · The Arabidopsis Book · doi:10.1199/tab.0127 · Cited by 298
Metadata
- Authors
- Heisler, M. G. B., Atkinson, A., Bylstra, Y. H., Walsh, R., & Smyth, D. R.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2001-04-01
- Volume
- 128
- Issue
- 7
- Pages
- 1089-1098
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2098325341
- Cited by
- 300
- References
- 42
- FWCI
- 15.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- Heisler, M. G. B., Atkinson, A., Bylstra, Y. H., Walsh, R., & Smyth, D. R. (2001). SPATULA, a gene that controls development of carpel margin tissues in Arabidopsis, encodes a bHLH protein. Development. https://doi.org/10.1242/dev.128.7.1089
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