Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland

Cited by (273)

Items 101–200 of 273

1. Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth
   Zhe Ying, Madeline Sandoval, Slobodan Beronja · 2018 · Nature Cell Biology
2. Phosphatase and Tensin Homologue Deleted on Chromosome 10 Deficiency Accelerates Tumor Induction in a Mouse Model of ErbB-2 Mammary Tumorigenesis
   Nathalie Dourdin, Babette Schade, Robert Lesurf, Michael T. Hallett, Robert J. Munn, Robert D. Cardiff, William J. Muller · 2008 · Cancer Research
3. Elevated PI3K signaling drives multiple Breast Cancer subtypes
   Jessica R. Adams, Nathan F. Schachter, Jeff C. Liu, Eldad Zacksenhaus, Sean E. Egan · 2011 · Oncotarget
4. Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis
   J S Richards, H-Y Fan, Z Liu, Mayra F. Tsoi, M.-N. Lague, Alexandre Boyer, Derek Boerboom · 2011 · Oncogene
5. A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila
   Rodney A. Stewart, Daming Li, He Huang, Tian Xu · 2003 · Oncogene
6. Transforming Acidic Coiled Coil 1 Promotes Transformation and Mammary Tumorigenesis
   Megan Cully, Jessica Shiu, Roland P. Piekorz, William J. Muller, Susan J. Done, Tak W. Mak · 2005 · Cancer Research
7. The role of IGFBP-5 in mammary gland development and involution
   Gordon J. Allan, James M Beattie, David J. Flint · 2004 · Domestic Animal Endocrinology
8. Akt is required for Stat5 activation and mammary differentiation
   Chien-Chung Chen, Robert B. Boxer, Douglas B. Stairs, Carla P. Portocarrero, Rachel Helen Horton, James V. Alvarez, Morris J. Birnbaum, Lewis A. Chodosh · 2010 · Breast Cancer Research
9. Mammalian Target of Rapamycin–Dependent Acinar Cell Neoplasia after Inactivation of Apc and Pten in the Mouse Salivary Gland: Implications for Human Acinic Cell Carcinoma
   Cassandra R. Diegel, Kathleen R. Cho, Adel K. El‐Naggar, Bart O. Williams, Charlotta J. Lindvall · 2010 · Cancer Research
10. Signal Transduction in Transgenic Mouse Models of Human Breast Cancer—Implications for Human Breast Cancer
    Richard Marcotte, William J. Muller · 2008 · Journal of Mammary Gland Biology and Neoplasia
11. PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer
    Marina Riggio, María L. Polo, Matı́as Blaustein, Alejandro Colman‐Lerner, Isabel Alicia Lüthy, Claudia Lanari, Virginia Novaro · 2011 · Carcinogenesis
12. Minireview: Physiological and Pathological Actions of RAS in the Ovary
    Heng‐Yu Fan, JoAnne S. Richards · 2009 · Molecular Endocrinology
13. Mouse Models of Breast Cancer
    Kazuhito Sakamoto, Jeffrey W. Schmidt, Kay‐Uwe Wagner · 2015 · Methods in molecular biology
14. mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis
    Meghan M. Morrison, Christian D. Young, Shan Wang, Tammy Sobolik, Violeta M. Sanchez, Donna J. Hicks, Rebecca S. Cook, Dana M. Brantley‐Sieders · 2015 · PLoS Genetics
15. Virginal Mammary Hypertrophy: A Meta-Analysis and Treatment Algorithm
    Ian C. Hoppe, Priti P. Patel, Carol J Singer-Granick, Mark S. Granick · 2011 · Plastic & Reconstructive Surgery
16. Activation of phosphatidylinositol 3-kinase by membrane localization of p110α predisposes mammary glands to neoplastic transformation
    Renner, Oliver, Blanco-Aparicio, Carmen, Grassow, Maja, Cañamero, Marta, Leal, Juan F.M., Carnero, Amancio · 2008 · Cancer Research
17. An inducible knock-out mouse to model cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
    Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Marı́a Santacana, Judit Pallarés, Sónia Gatius, Laura Bergadà, Óscar Maiques, Xavier Matías‐Guiu, Xavier Dolcet · 2013 · Disease Models & Mechanisms
18. Mice expressing myrAKT1 in the mammary gland develop carcinogen-induced ER-positive mammary tumors that mimic human breast cancer
    Carmen Blanco‐Aparicio, Lucía Pérez-Gallego, Belén Pequeño, Juan Fernando Martínez-Leal, Oliver Renner, Amancio Carnero · 2006 · Carcinogenesis
19. Simultaneous loss of the DLC1 and PTEN tumor suppressors enhances breast cancer cell migration
    Johanna Heering, Patrik Erlmann, Monilola A. Olayioye · 2009 · Experimental Cell Research
20. Loss of PPARγ expression in mammary secretory epithelial cells creates a pro‐breast tumorigenic environment
    Anthony J. Apostoli, Graham Skelhorne‐Gross, Rachel E. Rubino, Nichole T. Peterson, Michael A. Di Lena, Mark M. Schneider, Sandip Sengupta, Christopher J.B. Nicol · 2013 · International Journal of Cancer
21. PI3K regulates branch initiation and extension of cultured mammary epithelia via Akt and Rac1 respectively
    Wenting Zhu, Celeste M. Nelson · 2013 · Developmental Biology
22. In utero exposure to maternal diets containing soy protein isolate, but not genistein alone, protects young adult rat offspring from NMU-induced mammary tumorigenesis
    Ying Su, Renea R. Eason, Y. Geng, Sara R. Till, Thomas M. Badger, Frank A. Simmen · 2006 · Carcinogenesis
23. PTEN deletion leads to deregulation of antioxidants and increased oxidative damage in mouse embryonic fibroblasts
    Yanying Huo, Gang Li, Ruifeng Duan, Qiao Gou, FU Chun-ling, Yingchun Hu, Boqiang Song, Zhihua Yang, De-Chang Wu, Ping‐Kun Zhou · 2008 · Free Radical Biology and Medicine
24. Genistein-induced differentiation of breast cancer stem/progenitor cells through a paracrine mechanism
    YANCHEN LIU, TIANBIAO ZOU, SHUHUAI WANG, Hong Chen, Dongju Su, Xiaona Fu, Qingyuan Zhang, Xinmei Kang · 2016 · International Journal of Oncology
25. Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened
    Adriana P. Visbal, Heather L. LaMarca, Hugo J. Villanueva, Michael Joseph Toneff, Yi Li, Jeffrey M. Rosen, Michael T. Lewis · 2011 · Developmental Biology
26. Mouse models of PIK 3 CA mutations: one mutation initiates heterogeneous mammary tumors
    Shany Koren, Mohamed Bentires‐Alj · 2013 · FEBS Journal
27. Distinct Effects of EGFR Ligands on Human Mammary Epithelial Cell Differentiation
    Chandrani Mukhopadhyay, Xiangshan Zhao, Dulce M. Maroni, Vimla Band, Mayumi Naramura · 2013 · PLoS ONE
28. Ptch1is required locally for mammary gland morphogenesis and systemically for ductal elongation
    Ricardo Moraes, Hong Chang, Nikesha Harrington, John David Landua, Jonathan T. Prigge, Timothy F. Lane, Brandon J. Wainwright, Paul A. Hamel, Michael T. Lewis · 2009 · Development
29. Dietary Exposure to Whey Proteins Alters Rat Mammary Gland Proliferation, Apoptosis, and Gene Expression during Postnatal Development
    Renea R. Eason, Michael C. Velarde, Leon Chatman, Sara R. Till, Yan Geng, Matthew Eric Ferguson, Thomas M. Badger, Rosalia C.M. Simmen · 2004 · Journal of Nutrition
30. Genetically engineered mouse models of PI3K signaling in breast cancer
    Sjoerd Klarenbeek, Martine H. van Miltenburg, Jos Jonkers · 2013 · Molecular Oncology
31. MicroRNA Expression Profiling of Lactating Mammary Gland in Divergent Phenotype Swine Breeds
    Jing Peng, Junsheng Zhao, Yifei Shen, Haiguang Mao, Xu NingYing · 2015 · International Journal of Molecular Sciences
32. Secreted factors derived from obese visceral adipose tissue regulate the expression of breast malignant transformation genes
    Ana Belen Crujeiras, Begoña Cabia Fernández, Marcos C. Carreira, María Amil, Juan Fernando Cueva, Sara Andrade, Luisa Maria Seoane, María Pardo, Aurelio M. Sueiro, Javier Baltar et al. · 2015 · International Journal of Obesity
33. Phosphatase and tensin homologue deleted on chromosome 10
    Imran Haruna Abdulkareem, Maria Blair · 2013 · Nigerian Medical Journal
34. BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization
    Cynthia L. Forsman, Brandon Ng, Rachel Heinze, Claire Kuo, Consolato Maria Sergi, Rajaram Gopalakrishnan, Douglas Yee, Daniel Graf, Kathryn L. Schwertfeger, Anna Petryk · 2012 · Developmental Biology
35. Faithfull Modeling of PTEN Loss Driven Diseases in the Mouse
    Caterina Nardella, Arkaitz Carracedo, Leonardo Salmena, Pier Paolo Pandolfi · 2010 · Current topics in microbiology and immunology
36. PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells
    Chiara Zagni, Luciana O. Almeida, Tarek Balan, Marco Antônio Trevizani Martins, Luciana K. Rosselli‐Murai, Pétros Papagerakis, ROGERIO MORAES CASTILHO, CRISTIANE HELENA SQUARIZE · 2017 · Stem Cell Reports
37. Gene-targeting reveals physiological roles and complex regulation of the phosphoinositide 3-kinases
    Lazaros C. Foukas, Klaus Okkenhaug · 2003 · Archives of Biochemistry and Biophysics
38. Exploring the Gain of Function Contribution of AKT to Mammary Tumorigenesis in Mouse Models
    Carmen Blanco‐Aparicio, Marta Cañamero, Yolanda Cecilia, Belén Pequeño, Oliver Renner, Irene Ferrer, Amancio Carnero · 2010 · PLoS ONE
39. Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1
    Fredrik M. Berglund, Nimmi R. Weerasinghe, L Davidson, Jina Lim, Britta Johanna Eickholt, Nicholas R. Leslie · 2012 · Oncogene
40. PTEN Deletion Leads to Up-regulation of a Secreted Growth Factor Pleiotrophin
    Gang Li, Yingchun Hu, Yanying Huo, Minli Liu, Dan Freeman, Jing Gao, Xin Liu, De-Chang Wu, Hong Wu · 2006 · Journal of Biological Chemistry
41. Basal Cell Carcinoma and the Carcinogenic Role of Aberrant Hedgehog Signaling
    Anna Saran · 2010 · Future Oncology
42. Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer
    Ivana Heřmanová, Patricia Zúñiga-García, Alfredo Caro‐Maldonado, Sonia Fernández‐Ruiz, Fernando Salvador, Natalia Martín-Martín, Amaia Zabala‐Letona, Marc Núnez-Ollé, Verónica Torrano, Laura Camacho et al. · 2020 · The Journal of Experimental Medicine
43. Advances in Rodent Models for Breast Cancer Formation, Progression, and Therapeutic Testing
    Chong Liu, Pei Wu, Ailin Zhang, Xiaoyun Mao · 2021 · Frontiers in Oncology
44. Transgenic mouse models of breast cancer
    Angelina T. Regua, Austin Arrigo, Daniel L. Doheny, Grace L. Wong, Hui‐Wen Lo · 2021 · Cancer Letters
45. Hunk negatively regulates c-myc to promote Akt-mediated cell survival and mammary tumorigenesis induced by loss of Pten
    Elizabeth Shinmay Yeh, George K. Belka, Ann E. Vernon, Chien-Chung Chen, Jason J. Jung, Lewis A. Chodosh · 2013 · Proceedings of the National Academy of Sciences
46. Involvement of the phosphoinositide 3-kinase/Akt signaling pathway in the resistance to therapeutic treatments of human leukemias.
    Alberto Maria Martelli, Giovanna Tabellini, Roberta Bortul, Pier Luigi Tazzari, Alessandra Cappellini, Anna Maria Billi, Lucio Cocco · 2005 · PubMed
47. Transgenic mouse models for the prevention of breast cancer
    Qiang Shen, Powel H. Brown · 2005 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
48. PTEN Loss Promotes rasHa-Mediated Papillomatogenesis via Dual Up-Regulation of AKT Activity and Cell Cycle Deregulation but Malignant Conversion Proceeds via PTEN-Associated Pathways
    Denggao Yao, Claire L. Alexander, Jean A. Quinn, Michael Porter, Hong Wu, David A. Greenhalgh · 2006 · Cancer Research
49. PTEN Mouse Models of Cancer Initiation and Progression
    Yu-Ru Lee, Pier Paolo Pandolfi · 2019 · Cold Spring Harbor Perspectives in Medicine
50. Disruption of reelin signaling alters mammary gland morphogenesis
    Elvira Khialeeva, Timothy F. Lane, Ellen M. Carpenter · 2011 · Development
51. Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis
    Hua Zhao, Elisha Martin, Fatimah Kh. Matalkah, Neal Shah, Alexey V. Ivanov, John Michael Ruppert, Paul R. Lockman, Yehenew M. Agazie · 2018 · Oncogene
52. Everolimus Nanoformulation in Biological Nanoparticles Increases Drug Responsiveness in Resistant and Low-Responsive Breast Cancer Cell Lines
    Arianna Bonizzi, Marta Truffi, Marta Sevieri, Raffaele Allevi, Leopoldo Sitia, Roberta Ottria, Luca Sorrentino, Cristina Sottani, Sara Negri, Elena Grignani et al. · 2019 · Pharmaceutics
53. Nonsurgical Management of Fibroadenoma and Virginal Breast Hypertrophy
    Katie Jones, Sandhya Pruthi · 2013 · Seminars in Plastic Surgery
54. Cell non-autonomous function of daf-18/PTEN in the somatic gonad coordinates somatic gonad and germline development in C. elegans dauer larvae
    Claudia C. Tenen, I. Greenwald · 2019 · Current Biology
55. Androgen Resistance in Female Mice Increases Susceptibility to DMBA-Induced Mammary Tumors
    Ulla Simanainen, Yan Gao, Kirsty A. Walters, Geoff Watson, Reena Desai, Mark Jimenez, David J. Handelsman · 2012 · Hormones and Cancer
56. Targeted Expression of GLI1 in the Salivary Glands Results in an Altered Differentiation Program and Hyperplasia
    Marie Fiaschi, Åsa Kolterud, Mats Nilsson, Rune Toftgård, Björn Rozell · 2011 · American Journal Of Pathology
57. Decreased lactation capacity and altered milk composition in insulin receptor substrate null mice is associated with decreased maternal body mass and reduced insulin-dependent phosphorylation of mammary Akt
    Darryl L. Hadsell, Walter Olea, Nicole A. Lawrence, Jessy Rose George, Daniel Torres, Takahashi Kadowaki, Adrian V. Lee · 2007 · Journal of Endocrinology
58. MMTV-Cre transgenes can adversely affect lactation: Considerations for conditional gene deletion in mammary tissue
    Gertraud W. Robinson, Lothar G. Hennighausen · 2011 · Analytical Biochemistry
59. Androgen Receptor Inactivation Resulted in Acceleration in Pubertal Mammary Gland Growth, Upregulation of ERα Expression, and Wnt/β-Catenin Signaling in Female Mice
    Yan Gao, Kirsty A. Walters, Reena Desai, Hong Zhou, David J. Handelsman, Ulla Simanainen · 2014 · Endocrinology
60. Role of PTEN/PI3K pathway in endothelial cells
    Akira Suzuki, K. Hamada, Takehiko Sasaki, Tak W. Mak, Toru Nakano · 2007 · Biochemical Society Transactions
61. Tumour-suppressor function in the nervous system
    Suzanne J. Baker, Peter J. McKinnon · 2004 · Nature reviews. Cancer
62. Role of the PTEN signaling pathway in autism spectrum disorder
    Jingwen Lv, Tian‐Lin Cheng, Zilong Qiu, Wenhao Zhou · 2013 · Neuroscience Bulletin
63. Conditional Knockout Mouse Models of Cancer
    Chu‐Xia Deng · 2014 · Cold Spring Harbor Protocols
64. Re-inforcing the cell death army in the fight against breast cancer
    Clara Oudenaarden, Robert A. H. van de Ven, Patrick W.B. Derksen · 2018 · Journal of Cell Science
65. Targeting the Rna-Binding Protein Sam68 As A Treatment For Cancer?
    Kiven Erique Lukong, Stéphane Richard · 2007 · Future Oncology
66. A new protoapigenone analog RY10-4 induces apoptosis and suppresses invasion through the PI3K/Akt pathway in human breast cancer
    Qianying Yuan, Shaoxin Cai, Xuenong Zhang, Ziwei Liu, Zhaoming Li, Xuelai Luo, Chaomei Xiong, Jianping Wang, Junbo Hu, Jinlan Ruan · 2012 · Cancer Letters
67. Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling
    Li Li, Jinxia Sun, Xiaoqi Wang, Xiaokai Liu, Xianxiong Chen, Bo Zhang, Zhendan He, Dong-Zhou Liu, Lixin Chen, Liwei Wang et al. · 2017 · Oncotarget
68. PI3K signaling in the regulation of branching morphogenesis
    Wenting Zhu, Celeste M. Nelson · 2012 · Biosystems
69. Genetic modelling of the PTEN/AKT pathway in cancer research
    Oliver Renner, Carmen Blanco‐Aparicio, Amancio Carnero · 2008 · Clinical & Translational Oncology
70. PtdIns(3,4,5)P 3 -dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis
    Nuthasuda Srijakotre, Heng-Jia Liu, Max Nobis, Joey Man, Hon Yan Kelvin Yip, Antonella Papa, Helen E. Abud, Kurt I. Anderson, Heidi C. E. Welch, Tony Tiganis et al. · 2020 · Proceedings of the National Academy of Sciences
71. The PTEN and Myotubularin Phosphoinositide 3-Phosphatases: Linking Lipid Signalling to Human Disease
    Elizabeth M. Davies, David A. Sheffield, Priyanka Tibarewal, Clare G. Fedele, Christina Anne Mitchell, Nicholas R. Leslie · 2012 · Sub-cellular biochemistry/Subcellular biochemistry
72. An essential role for Gα i2 in Smoothened-stimulated epithelial cell proliferation in the mammary gland
    Hugo J. Villanueva, Adriana P. Visbal, Nadine F. Obeid, Andrew Q. Ta, Adeel A. Faruki, Meng-Fen Wu, Susan Galloway Hilsenbeck, Chad A. Shaw, Peng Yu, Nicholas W. Plummer et al. · 2015 · Science Signaling
73. Targeting Gi/o protein–coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy
    Cancan Lyu, Yuanchao Ye, Maddison Lensing, Kay‐Uwe Wagner, Ronald J. Weigel, Songhai Chen · 2021 · JCI Insight
74. The Insulin-Like Growth Factor System in Normal Mammary Gland Function
    Darryl L. Hadsell · 2003 · Breast Disease
75. Forced involution of the functionally differentiated mammary gland by overexpression of the pro‐apoptotic protein bax
    Edmund B. Rucker, Amber N. Hale, David C. Durtschi, Kazuhito Sakamoto, Kay‐Uwe Wagner · 2010 · genesis
76. Mouse Models of Human Familial Cancer Syndromes
    Jerrold Michael Ward, Deborah E. Devor-Henneman · 2004 · Toxicologic Pathology
77. Breast Physiology
    Susie Xinying Sun, Zeynep Bostanci, Rena B. Kass, Anne T. Mancino, Arlan L. Rosenbloom, V. Suzanne Klimberg, Kirby I. Bland · 2017 · Elsevier eBooks
78. A Premalignant Cell-Based Model for Functionalization and Classification of PTEN Variants
    Jesse T. Chao, Rocio Hollman, Warren M. Meyers, Fabian Meili, Kenneth A. Matreyek, Pamela Dean, Douglas M. Fowler, Kurt Z. Haas, Calvin D. Roskelley, Christopher J. R. Loewen · 2020 · Cancer Research
79. Lobular Breast Cancer: Pathology, Biology, and Options for Clinical Intervention
    Eva J. Vlug, Cigdem Ercan, Elsken van der Wall, P. J. van Diest, Patrick W.B. Derksen · 2013 · Archivum Immunologiae et Therapiae Experimentalis
80. Virginal breast hypertrophy of an 11‐year‐old girl
    Ildi H. Koves, Margaret Zacharin · 2007 · Journal of Paediatrics and Child Health
81. PTEN, Longevity and Age-Related Diseases
    Izak Tait, Yan Li, Jun Lu · 2013 · Biomedicines
82. grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten +/- mice
    Megan Cully, Andrew Elia, Siew Hwa Ong, Vuk Stambolic, Tony J. Pawson, Ming‐Sound Tsao, Tak W. Mak · 2004 · Proceedings of the National Academy of Sciences
83. Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21WAF-induced differentiation triggered by GSK3β inactivation and reduced AKT activity
    Denggao Yao, Claire L. Alexander, Jean A. Quinn, Weng-Chyn Chan, Hong Wu, David A. Greenhalgh · 2008 · Journal of Cell Science
84. PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland
    Shore, Amy N., Chang, Chi-Hsuan, Kwon, Oh-Joon, Weston, Matthew C., Zhang, Mei, Xin, Li, Rosen, Jeffrey M. · 2016 · Developmental Biology
85. Dasatinib inhibits mammary tumour development in a genetically engineered mouse model
    Saadia A. Karim, Helen Creedon, Hitesh Patel, Neil O. Carragher, Jennifer P. Morton, William J. Muller, Thomas R. Jeffry Evans, Barry A. Gusterson, Owen James Sansom, Valerie G. Brunton · 2013 · The Journal of Pathology
86. Lactation Defect with Impaired Secretory Activation in AEBP1-Null Mice
    Lei Zhang, Shannon P. Reidy, Oleg Bogachev, Brian Keith Hall, Amin F. Majdalawieh, Jungsil Ro · 2011 · PLoS ONE
87. The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study
    Ying E., Qian Yu, Tao Sun, Hang Xue, Xuerong Zhao, Hua‐chuan Zheng · 2023 · BMC Cancer
88. eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
    Warapen Treekitkarnmongkol, Luisa Maren Solis, Deivendran Sankaran, Mihai Gagea, Pankaj Kumar Singh, Ragini M. Mistry, Tristian Nguyen, Kazuharu Kai, Jiajun Liu, Kaori Sasai et al. · 2024 · Science Signaling
89. Juvenile Breast Hypertrophy: A Successful Breast Reduction of 14.9% Body Weight without Recurrence in a 5-Year Follow-Up
    Akmal Hisham, Marzida Abd Latib, Normala Basiron · 2017 · Case Reports in Surgery
90. Construction of transgenic swine with induced expression of Cre recombinase
    L. Chen, L. Li, Dongqing Pang, Zhiming Li, T. Wang, Meng Zhang, N. Song, S. Yan, L. Lai, Hongsheng Ouyang · 2010 · animal
91. Cytokeratin 19 promoter directs the expression of Cre recombinase in various epithelia of transgenic mice
    Guifeng Zhao, Shuang Zhao, Jia-Jie Liu, Jicheng Wu, Hao-Yu He, Xiaoqing Ding, Xuewen Yu, Keqiang Huang, Zhijie Li, Hua‐chuan Zheng · 2017 · Oncotarget
92. MicroRNA‑23b‑3p promotes pancreatic cancer cell tumorigenesis and metastasis via the JAK/PI3K and Akt/NF‑κB signaling pathways
    Yunan Zhang, Dayang Chen, Guoqiang Zhang, Xiongbo Wu, Liang-Yun Zhou, Yexin Lin, Junli Ding, Fangmei An, Qiang Zhan · 2020 · Oncology Letters
93. 15-Deoxy-Δ12,14-prostaglandin J2 activates PI3K-Akt signaling in human breast cancer cells through covalent modification of the tumor suppressor PTEN at cysteine 136
    Jinyoung Suh, Do‐Hee Kim, Eun‐Hee Kim, Sin‐Aye Park, Jongmin Park, Jeong‐Hoon Jang, Su‐Jung Kim, Hye‐Kyung Na, Nam Doo Kim, Nam‐Jung Kim et al. · 2018 · Cancer Letters
94. Regulation of Stem Cell Systems by PI3K/Akt Signaling
    Tohru Kimura, Toru Nakano · 2009 · Humana Press eBooks
95. Androgen actions via androgen receptor promote PTEN inactivation induced uterine cancer
    Jaesung Peter Choi, Reena Desai, Yu Zheng, Yao Mu, Qihan Dong, Geoff Watson, David J. Handelsman, Ulla Simanainen · 2015 · Endocrine Related Cancer
96. DNA repair, insulin signaling and sirtuins: at the crossroads between cancer and aging
    Raúl Mostoslavsky · 2008 · Frontiers in bioscience
97. Targeting the mTOR Pathway for the Prevention of ER-Negative Breast Cancer
    Abhijit Mazumdar, William M. Tahaney, Jamal L. Hill, Yun Zhang, Sumankalai Ramachandran, Jitesh D. Kawedia, Jing Qian, Alejandro Contreras, Michelle I. Savage, Lana A. Vornik et al. · 2022 · Cancer Prevention Research
98. Pten Regulates Epithelial Cytodifferentiation during Prostate Development
    Isabel B. Lokody, Jeffrey C. Francis, Jennifer R. Gardiner, Janine Terra Erler, Amanda Swain · 2015 · PLoS ONE
99. Low expression of phosphatase and tensin homolog in clear-cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway
    Jun Chen, He Zhu, Yan Zhang, Manhua Cui, Liying Han, ZHAN-HUI JIA, Ling Wang, Hong Teng, Lining Miao · 2015 · Molecular Medicine Reports
100. Elevated V–ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer
     Amro H. Mohammad, Sung-Hoon Kim, Nicholas Bertos, Wissal El-Assaad, Ipshita Nandi, Harvey W. Smith, Jieyi Yang, Owen J. Chen, Isabelle Gamache, Trisha Rao et al. · 2020 · Molecular Cancer Research