Cited by 341Cancer-related Molecular PathwaysSignaling Pathways in DiseaseGenomics and Chromatin Dynamics

Transcriptional regulation of the cyclin D1 gene at a glance

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Klein, Eric A., Assoian, Richard K.·2008·Journal of Cell Science

Abstract

Regulated progression through the cell cycle requires sequential expression of a family of proteins called cyclins. Upon their induction, cyclins form complexes with specific cyclin-dependent kinases (CDKs), creating active holoenzymes that phosphorylate target proteins that are required for cell-

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Authors
Klein, E. A., & Assoian, R. K.
Affiliations
University of Pennsylvania (US)
Corresponding author
Assoian, Richard K.
Venue
Journal of Cell Science
Published
2008-12-01
Volume
121
Issue
23
Pages
3853-3857
ISSN
  • 0021-9533 (ISSN-L)
  • 1477-9137
OpenAlex
W2134977493
Cited by
341
References
80
Citations by year
2026: 7 · 2025: 8 · 2024: 11 · 2023: 17 · 2022: 13 · 2021: 19 · 2020: 32 · 2019: 20 · 2018: 28 · 2017: 23 · 2016: 21 · 2015: 28 · 2014: 28 · 2013: 30 · 2012: 27
FWCI
0.86
Type
journal article
Language
en
Open access
Locations
  • Journal of Cell Science (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Cancer Institute (R01CA072639)
Topics
  • Health Sciences › Medicine › Oncology › Cancer-related Molecular Pathways
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Signaling Pathways in Disease
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Keywords
cyclin D1, transcriptional regulation, cyclins, cyclin-dependent kinases, cell cycle progression, gene expression regulation
MeSH terms
Animals, Binding Sites, Gene Expression Regulation, Humans, Promoter Regions, Genetic, Transcription, Genetic, Cyclin D1

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