The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Integrin cytoplasmic domain-binding proteins
Open accessAbstract
Integrins are a large family of cell surface receptors that mediate cell adhesion and influence migration, signal transduction, and gene expression. The cytoplasmic domains of integrins play a pivotal role in these integrin-mediated cellular functions. Through interaction with the cytoskeleton, signaling molecules, and other cellular proteins, integrin cytoplasmic domains transduce signals from both the outside and inside of the cell and regulate integrin-mediated biological functions. Identification and functional analyses of integrin cytoplasmic domain-binding proteins have been pursued intensively. In recent years, more cellular proteins have been reported to directly interact with integrin cytoplasmic domains and some of these interactions may play important roles in integrin-mediated biological responses. Integrin β chains, for example, interact with actin-binding proteins (e.g. talin and filamin), which form mechanical links to the cytoskeleton. These and other proteins (e.g. FAK, ILK and novel proteins such as TAP20) might also link integrins to signaling mechanisms and, in some cases (e.g. JAB1) mediate integrin-dependent gene regulation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Integrins: Versatility, modulation, and signaling in cell adhesion
Hynes, R. O. (1992) · Cell · doi:10.1016/0092-8674(92)90115-s · Cited by 9,859
Integrins: Emerging Paradigms of Signal Transduction
Schwartz, M. A., Schaller, M. D., & Ginsberg, M. H. (1995) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cb.11.110195.003001 · Cited by 1,594
Self-citationInteraction of plasma membrane fibronectin receptor with talin—a transmembrane linkage
Horwitz, A., Duggan, K., Buck, C., Beckerle, M. C., & Burridge, K. (1986) · Nature · doi:10.1038/320531a0 · Cited by 1,192
Fox, J. W., Lamperti, E. D., Ekşioğlu, Y. Z., Hong, S. E., Feng, Y., Graham, D. A., Scheffer, I. E., Dobyns, W. B., Hirsch, B. A., Radtke, R. A., et al. (1998) · Neuron · doi:10.1016/s0896-6273(00)80651-0 · Cited by 880
An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.
Otey, C. A., Pavalko, F. M., & Burridge, K. (1990) · The Journal of cell biology · doi:10.1083/jcb.111.2.721 · Cited by 843
Calderwood, D. A., Zent, R., Grant, R., Rees, D. J. G., Hynes, R. O., & Ginsberg, M. H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.40.28071 · Cited by 720
Self-citationWary, K. K., Mariotti, A., Zurzolo, C., & Giancotti, F. G. (1998) · Cell · doi:10.1016/s0092-8674(00)81604-9 · Cited by 718
Integrin cytoplasmic domains mediate inside-out signal transduction
O'Toole, T., Katagiri, Y., Faull, R., Peter, K., Tamura, R., Quaranta, V, Loftus, J., Shattil, S., & Ginsberg, M. (1994) · The Journal of cell biology · doi:10.1083/jcb.124.6.1047 · Cited by 661
Self-citationFocal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.
Schaller, M. D., Otey, C. A., Hildebrand, J. D., & Parsons, J. T. (1995) · The Journal of cell biology · doi:10.1083/jcb.130.5.1181 · Cited by 622
Focal adhesions – the cytoskeletal connection
Critchley, D. R. (2000) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)00067-8 · Cited by 572
Cited by
Immune cell migration in inflammation: present and future therapeutic targets
Luster, A. D., Alon, R., & von Andrian, U. H. (2005) · Nature Immunology · doi:10.1038/ni1275 · Cited by 1,313
Function and Genetics of Dystrophin and Dystrophin-Related Proteins in Muscle
Blake, D. J., Weir, A., Newey, S. E., & Davies, K. E. (2002) · Physiological Reviews · doi:10.1152/physrev.00028.2001 · Cited by 1,242
The final steps of integrin activation: the end game
Shattil, S. J., Kim, C., & Ginsberg, M. H. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2871 · Cited by 1,086
Self-citationSignaling Properties of Hyaluronan Receptors
Turley, E. A., Noble, P. W., & Bourguignon, L. Y. W. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.r100038200 · Cited by 1,041
Berrier, A. L., & Yamada, K. M. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21237 · Cited by 957
Metadata
- Authors
- Liu, S., Calderwood, D. A., & Ginsberg, M. H.
- Venue
- Journal of Cell Science
- Publisher
- The Company of Biologists
- Published
- 2000-10-15
- Volume
- 113
- Issue
- 20
- Pages
- 3563-3571
- ISSN
- 0021-9533 (ISSN-L)
- 1477-9137
- OpenAlex
- W2164330595
- Cited by
- 572
- References
- 84
- FWCI
- 15.60
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Integrin cytoplasmic domain-binding proteins. https://app.cochat.ai/papers/10.1242/jcs.113.20.3563
- The paper
- Liu, S., Calderwood, D. A., & Ginsberg, M. H. (2000). Integrin cytoplasmic domain-binding proteins. Journal of Cell Science. https://doi.org/10.1242/jcs.113.20.3563
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
