The DOI matches its Crossref record; 92 of the 92 references it cites were found in a registry or an index.
The organisation and functions of local Ca2+ signals
Abstract
Calcium (Ca2+) is a ubiquitous intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation. The ability of a simple ion such as Ca2+ to play a pivotal role in cell biology results from the facility that cells have to shape Ca2+ signals in space, time and amplitude. To generate and interpret the variety of observed Ca2+ signals, different cell types employ components selected from a Ca2+ signalling ‘toolkit’, which comprises an array of homeostatic and sensory mechanisms. By mixing and matching components from the toolkit, cells can obtain Ca2+ signals that suit their physiology. Recent studies have demonstrated the importance of local Ca2+ signals in defining the specificity of the interaction of Ca2+ with its targets. Furthermore, local Ca2+ signals are the triggers and building blocks for larger global signals that propagate throughout cells.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The versatility and universality of calcium signalling
Berridge, M. J., Lipp, P., & Bootman, M. D. (2000) · Nature Reviews Molecular Cell Biology · doi:10.1038/35036035 · Cited by 5,701
Self-citationClose Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca 2+ Responses
Rizzuto, R., Pinton, P., Carrington, W., Fay, F. S., Fogarty, K. E., Lifshitz, L. M., Tuft, R. A., & Pozzan, T. (1998) · Science · doi:10.1126/science.280.5370.1763 · Cited by 2,257
Berridge, M. J. (1998) · Neuron · doi:10.1016/s0896-6273(00)80510-3 · Cited by 2,188
Self-citationCalcium - a life and death signal
Berridge, M. J., Bootman, M. D., & Lipp, P. (1998) · Nature · doi:10.1038/27094 · Cited by 2,063
Self-citationCalmodulin: a prototypical calcium sensor
Chin, D., & Means, A. R. (2000) · Trends in Cell Biology · doi:10.1016/s0962-8924(00)01800-6 · Cited by 1,525
Relaxation of Arterial Smooth Muscle by Calcium Sparks
Nelson, M. T., Cheng, H., Rubart, M., Santana, L. F., Bonev, A. D., Knot, H. J., & Lederer, W. J. (1995) · Science · doi:10.1126/science.270.5236.633 · Cited by 1,396
Histone acetylation and an epigenetic code
Turner, B. M. (2000) · BioEssays · doi:10.1002/1521-1878(200009)22:9<811::aid-bies6>3.0.co;2-g · Cited by 1,249
Elementary and global aspects of calcium signalling.
Berridge, M. J. (1997) · The Journal of Physiology · doi:10.1113/jphysiol.1997.sp021927 · Cited by 1,018
Self-citationNeher, E. (1998) · Neuron · doi:10.1016/s0896-6273(00)80983-6 · Cited by 1,010
Calmodulin supports both inactivation and facilitation of L-type calcium channels
Zühlke, R. D., Pitt, G. S., Deisseroth, K., Tsien, R. W., & Reuter, H. (1999) · Nature · doi:10.1038/20200 · Cited by 899
Cited by
Microdomains of Intracellular Ca2+: Molecular Determinants and Functional Consequences
Rizzuto, R., & Pozzan, T. (2006) · Physiological Reviews · doi:10.1152/physrev.00004.2005 · Cited by 1,206
Inositol Trisphosphate Receptor Ca2+Release Channels
Foskett, J. K., White, C., Cheung, K.-H., & Mak, D.-O. D. (2007) · Physiological Reviews · doi:10.1152/physrev.00035.2006 · Cited by 1,188
Activity-dependent regulation of dendritic growth and patterning
Wong, R. O. L., & Ghosh, A. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn941 · Cited by 635
Calcium microdomains: Organization and function
Berridge, M. J. (2006) · Cell Calcium · doi:10.1016/j.ceca.2006.09.002 · Cited by 525
Self-citationCa2+/Calmodulin-dependent Protein Kinases
Swulius, M. T., & Waxham, M. N. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8086-2 · Cited by 396
Metadata
- Authors
- Bootman, M. D., Lipp, P., & Berridge, M. J.
- Venue
- Journal of Cell Science
- Publisher
- The Company of Biologists
- Published
- 2001-06-15
- Volume
- 114
- Issue
- 12
- Pages
- 2213-2222
- ISSN
- 0021-9533 (ISSN-L)
- 1477-9137
- OpenAlex
- W2150942343
- Cited by
- 450
- References
- 92
- FWCI
- 18.41
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The organisation and functions of local Ca2+ signals. https://app.cochat.ai/papers/10.1242/jcs.114.12.2213
- The paper
- Bootman, M. D., Lipp, P., & Berridge, M. J. (2001). The organisation and functions of local Ca2+ signals. Journal of Cell Science. https://doi.org/10.1242/jcs.114.12.2213
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.