The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Oxygen Toxicity: A Radical Explanation
Abstract
During its reduction to water, O2 readily gives rise to dangerously reactive intermediates. This threat is diminished by families of defensive enzymes which include the superoxide dismutases, catalases and peroxidases. Free radical chain reactions are controlled by antioxidants, such as ascorbate and the tocopherols, and oxidative damage, which occurs in spite of these defenses, is largely repaired or is nullified by de novo biosynthesis. Yet some damage is sustained and it contributes to mutagenesis, to senescence and to numerous pathological processes.
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Cites
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
Li, Y., Huang, T.-T., Carlson, E. J., Melov, S., Ursell, P. C., Olson, J. L., Noble, L. J., Yoshimura, M. P., Berger, C., Chan, P. H., et al. (1995) · Nature Genetics · doi:10.1038/ng1295-376 · Cited by 1,789
Faster superoxide dismutase mutants designed by enhancing electrostatic guidance
Getzoff, E. D., Cabelli, D. E., Fisher, C. L., Parge, H. E., Viezzoli, M. S., Banci, L., & Hallewell, R. A. (1992) · Nature · doi:10.1038/358347a0 · Cited by 399
Electrostatic interactions in the reaction mechanism of bovine erythrocyte superoxide dismutase
Cudd, A., & Fridovich, I. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33779-7 · Cited by 211
Self-citation
Cited by
Stress Physiology of Lactic Acid Bacteria.
Papadimitriou, K., Alegría, Á., Bron, P. A., de Angelis, M., Gobbetti, M., Kleerebezem, M., Lemos, J. A., Linares, D. M., Ross, P., Stanton, C., et al. (2016) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00076-15 · Cited by 914
COPSE: A new model of biogeochemical cycling over Phanerozoic time
Bergman, N. M. (2004) · American Journal of Science · doi:10.2475/ajs.304.5.397 · Cited by 599
A comparative and evolutionary approach to oxidative stress in fish: A review
Birnie‐Gauvin, K., Costantini, D., Cooke, S. J., & Willmore, W. G. (2017) · Fish and Fisheries · doi:10.1111/faf.12215 · Cited by 478
Antioxidant activity of different fractions of Spirulina platensis protean extract
Piñero Estrada, J. (2001) · Il Farmaco · doi:10.1016/s0014-827x(01)01084-9 · Cited by 447
Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions
Reiter, R., Tan, D., Rosales-Corral, S., Galano, A., Zhou, X., & Xu, B. (2018) · Molecules · doi:10.3390/molecules23020509 · Cited by 393
Metadata
- Authors
- Fridovich, I.
- Venue
- Journal of Experimental Biology
- Publisher
- The Company of Biologists
- Published
- 1998-04-01
- Volume
- 201
- Issue
- 8
- Pages
- 1203-1209
- ISSN
- 0022-0949 (ISSN-L)
- 1477-9145
- OpenAlex
- W2149719174
- Cited by
- 857
- References
- 3
- FWCI
- 5.18
- Type
- journal article
- Language
- en
- Open access
- closed
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