The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The Human Gene Map for Performance and Health-Related Fitness Phenotypes: The 2005 Update
Abstract
The current review presents the 2005 update of the human gene map for physical performance and health-related fitness phenotypes. It is based on peer-reviewed papers published by the end of 2005. The genes and markers with evidence of association or linkage with a performance or fitness phenotype in sedentary or active people, in adaptation to acute exercise, or for training-induced changes are positioned on the genetic map of all autosomes and the X chromosome. Negative studies are reviewed, but a gene or locus must be supported by at least one positive study before being inserted on the map. By the end of 2000, in the early version of the gene map, 29 loci were depicted. In contrast, the 2005 human gene map for physical performance and health-related phenotypes includes 165 autosomal gene entries and QTL, plus five others on the X chromosome. Moreover, there are 17 mitochondrial genes in which sequence variants have been shown to influence relevant fitness and performance phenotypes. Thus, the map is growing in complexity. Unfortunately, progress is slow in the field of genetics of fitness and performance, primarily because the number of laboratories and scientists focused on the role of genes and sequence variations in exercise-related traits continues to be quite limited.
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Lahat, H., Pras, E., Olender, T., Avidan, N., Ben-Asher, E., Man, O., Levy-Nissenbaum, E., Khoury, A., Lorber, A., Goldman, B., et al. (2001) · The American Journal of Human Genetics · doi:10.1086/324565 · Cited by 655
Ivey, F. M., Roth, S. M., Ferrell, R. E., Tracy, B. L., Lemmer, J. T., Hurlbut, D. E., Martel, G. F., Siegel, E. L., Fozard, J. L., Metter, E. J., et al. (2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.11.m641 · Cited by 288
Self-citationLahat, H., Eldar, M., Levy-Nissenbaum, E., Bahan, T., Friedman, E., Khoury, A., Lorber, A., Kastner, D. L., Goldman, B., & Pras, E. (2001) · Circulation · doi:10.1161/01.cir.103.23.2822 · Cited by 266
Folland, J., Leach, B., Little, T., Hawker, K., Myerson, S., Montgomery, H., & Jones, D. (2000) · Experimental Physiology · doi:10.1111/j.1469-445x.2000.02057.x · Cited by 208
Obisesan, T. O., Leeuwenburgh, C., Phillips, T., Ferrell, R. E., Phares, D. A., Prior, S. J., & Hagberg, J. M. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000140060.13203.22 · Cited by 83
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Bouchard, C., Sarzynski, M. A., Rice, T. K., Kraus, W. E., Church, T. S., Sung, Y. J., Rao, D. C., & Rankinen, T. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00973.2010 · Cited by 422
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Adverse metabolic response to regular exercise: is it a rare or common occurrence?
Bouchard, C., Blair, S. N., Church, T. S., Earnest, C. P., Hagberg, J. M., Häkkinen, K., Jenkins, N. T., Karavirta, L., Kraus, W. E., Leon, A. S., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037887 · Cited by 404
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Metadata
- Authors
- RANKINEN, T., BRAY, M. S., HAGBERG, J. M., PÉRUSSE, L., ROTH, S. M., WOLFARTH, B., & BOUCHARD, C.
- Venue
- Medicine & Science in Sports & Exercise
- Published
- 2006-11
- Volume
- 38
- Issue
- 11
- Pages
- 1863-1888
- ISSN
- 0195-9131 (ISSN-L)
- OpenAlex
- W2004739732
- Cited by
- 734
- References
- 6
- FWCI
- 34.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Human Gene Map for Performance and Health-Related Fitness Phenotypes: The 2005 Update. https://app.cochat.ai/papers/10.1249/01.mss.0000233789.01164.4f
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- RANKINEN, T., BRAY, M. S., HAGBERG, J. M., PÉRUSSE, L., ROTH, S. M., WOLFARTH, B., & BOUCHARD, C. (2006). The Human Gene Map for Performance and Health-Related Fitness Phenotypes: The 2005 Update. Medicine & Science in Sports & Exercise. https://doi.org/10.1249/01.mss.0000233789.01164.4f
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