Heat Stress and Baroreflex Regulation ofBlood Pressure
Open accessAbstract
In healthy, noninjured, individuals, passive (i.e., nonexercising) whole-body heating has the potential to cause significant cardiovascular stress that may be second only to the cardiovascular stress associated with exercise. For example, such a heat stress can increase heart rate to well over 100 beats min(-1) with cardiac output increasing upward to 13 L min(-1). This increase in cardiac output is necessary to maintain blood pressure due to profound reductions in total vascular conductance associated with cutaneous vasodilation. These responses are accompanied with elevations in sympathetic activity and reductions in vascular conductance (i.e., increased vascular resistance) from noncutaneous beds. While heat-stressed, blood pressure control is compromised resulting in orthostatic intolerance. A plausible explanation for such an event is that heat stress impairs baroreflex responsiveness perhaps due to the reduced range by which baroreflexes can increase heart rate, cardiac output, sympathetic activity, and vascular resistance during a hypotensive challenge. Given that dynamic exercise has the potential to cause large increases in internal temperature, possibly a component of the response to exercise, with respect to baroreflex control of blood pressure, may be affected by the thermal load during the exercise bout. Within this context, the purpose of this review was to summarize findings investigating the effects of heat stress on baroreflex regulation of blood pressure.
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When exposed to a hot environment, the body reacts through active cutaneous vasodilation and sweating.
“When a person is exposed to a hot environment (hyperthermia), the body reacts specifically to this condition through active cutaneous vasodilation and sweating [33,34].”
From Human thermal perception and time of day: A review (2021) · cites this paper as [33]
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Human thermal perception and time of day: A review
Vellei, M., Chinazzo, G., Zitting, K.-M., & Hubbard, J. (2021) · Temperature · doi:10.1080/23328940.2021.1976004 · Cited by 45 · see citing works
- Authors
- CRANDALL, C. G.
- Affiliations
- Texas Health Dallas (US)
- Corresponding author
- CRANDALL, CRAIG G.
- ORCID
- CRANDALL, CRAIG G.
- Venue
- Medicine & Science in Sports & Exercise
- Published
- 2008-12
- Volume
- 40
- Issue
- 12
- Pages
- 2063-2070
- ISSN
- 0195-9131 (ISSN-L)
- PMC
- PMC2819365
- OpenAlex
- W1994610769
- Cited by
- 70
- References
- 64
- Citations by year
- 2026: 8 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 2 · 2021: 8 · 2020: 3 · 2019: 4 · 2018: 4 · 2017: 5 · 2016: 4 · 2015: 1 · 2014: 5 · 2013: 3 · 2012: 1
- FWCI
- 0.47
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Medicine & Science in Sports & Exercise (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (HL61388, R01HL067422, R01HL084072, HL-84072, R01HL061388, HL 67422)
- Topics
- Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- heat stress, baroreflex, blood pressure regulation, orthostatic intolerance, cutaneous vasodilation, cardiac output, heart rate, sympathetic activity, vascular conductance, exercise thermoregulation
- MeSH terms
- Blood Pressure, Heart Rate, Humans, Receptors, Adrenergic, Synapses, Vasoconstriction, Baroreflex, Heat Stress Disorders
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