Cited by 100Cardiovascular Syncope and Autonomic DisordersMigraine and Headache StudiesNeurosurgical Procedures and Complications

Orthostatic headaches without CSF leak in postural tachycardia syndrome

Mokri, Bahram, Low, Phillip A.·2003·Neurology

Abstract

Four women age 17 to 28 years presented with orthostatic headaches as the most prominent feature of their symptom complex. None had CSF leak or intracranial hypotension. Autonomic studies showed evidence of orthostatic intolerance with tachycardia in all cases. Treatment of orthostatic intolerance, mainly with volume expansion, was only partially effective. Orthostatic headaches are not always caused by CSF leak or supine intracranial hypotension. Occasionally they may be the major clinical manifestation of postural tachycardia syndrome or orthostatic intolerance.

Integrity signals

Registry

Crossref · 10.1212/01.wnl.0000085868.37963.7d

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7 of 7 references verified0 citation errors · 0 not checkable

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  • Orthostatic headaches in POTS may be related to decreases in spinal venous pressure and cerebrospinal fluid volume due to absolute or orthostatic hypovolemia.

    “Orthostatic headaches may be related to decreases in spinal venous pressure and volume of cerebrospinal fluid due to an absolute or orthostatic hypovolemia [21].”

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Authors
Mokri, B., & Low, P. A.
Affiliations
Mayo Clinic (US)
Venue
Neurology
Published
2003-10-14
Volume
61
Issue
7
Pages
980-982
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W1996155377
Cited by
100
References
8
Citations by year
2026: 2 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 3 · 2021: 9 · 2020: 9 · 2019: 7 · 2018: 8 · 2017: 4 · 2016: 1 · 2015: 6 · 2014: 6 · 2013: 3 · 2012: 3
FWCI
4.15
Type
journal article
Language
en
Open access
closed
Locations
  • Neurology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Medicine › Psychiatry and Mental health › Migraine and Headache Studies
  • Health Sciences › Medicine › Neurology › Neurosurgical Procedures and Complications
Keywords
orthostatic headache, postural orthostatic tachycardia syndrome, orthostatic intolerance, cerebrospinal fluid leak, intracranial hypotension, autonomic dysfunction, volume expansion, young women
MeSH terms
Adolescent, Adult, Autonomic Nervous System Diseases, Diagnosis, Differential, Female, Craniocerebral Trauma, Headache, Humans, Posture, Subdural Effusion, Syncope, Syndrome, Tachycardia, Intracranial Hypotension, Neck Injuries

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