CoChat
Sign Up
Cited by 347Cardiovascular Effects of ExerciseCardiovascular and exercise physiologyCardiomyopathy and Myosin Studies

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

Disproportionate Exercise Load and Remodeling of the Athlete's Right Ventricle

LA GERCHE, ANDRÉ, HEIDBÜCHEL, HEIN, BURNS, ANDREW T., MOONEY, DON J., TAYLOR, ANDREW J., PFLUGER, HEINZ B., INDER, WARRICK J., MACISAAC, ANDREW I., PRIOR, DAVID L.·2011·Medicine & Science in Sports & Exercise
DOI 10.1249/mss.0b013e31820607a3
Open this paper in CoChat — free account

Abstract

Purpose There is evolving evidence that intense exercise may place a disproportionate load on the right ventricle (RV) when compared with the left ventricle (LV) of the heart. Using a novel method of estimating end-systolic wall stress (ES-σ), we compared the RV and LV during exercise and assessed whether this influenced chronic ventricular remodeling in athletes. Methods For this study, 39 endurance athletes (EA) and 14 nonathletes (NA) underwent resting cardiac magnetic resonance (CMR), maximal oxygen uptake (VO2), and exercise echocardiography studies. LV and RV end-systolic wall stress (ES-σ) were calculated using the Laplace relation (ES-σ = Pr/(2h)). Ventricular size and wall thickness were determined by CMR; invasive and Doppler echo estimates were used to measure systemic and pulmonary ventricular pressures, respectively; and stroke volume was quantified by Doppler echocardiography and used to calculate changes in ventricular geometry during exercise. Results In EA, compared with NA, resting CMR measures showed greater RV than LV remodeling. The ratios RV ESV/LV ESV (1.40 ± 0.23 vs 1.26 ± 0.12, P = 0.007) and RV mass/LV mass (0.29 ± 0.04 vs 0.25 ± 0.03, P = 0.012) were greater in EA than in NA. RVES-σ was lower at rest than LVES-σ (143 ± 44 vs 252 ± 49 kdyn · cm, P Conclusions Exercise induces a relative increase in RVES-σ which exceeds LVES-σ. In athletes, greater RV enlargement and greater wall thickening may be a product of this disproportionate load excess.

Overview

Integrity signals

Registry

Crossref · 10.1249/mss.0b013e31820607a3

Cites

42 of 42 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 42 references

Cited by

Sorted by citations

Items 101–200 of 346

Related

See all

Metadata

Authors
LA GERCHE, A., HEIDBÜCHEL, H., BURNS, A. T., MOONEY, D. J., TAYLOR, A. J., PFLUGER, H. B., INDER, W. J., MACISAAC, A. I., & PRIOR, D. L.
Affiliations
  • Universitair Ziekenhuis Leuven (BE)
  • St Vincent's Hospital Melbourne (AU)
  • Baker Heart and Diabetes Institute (AU)
  • The University of Melbourne (AU)
ORCID
Venue
Medicine & Science in Sports & Exercise
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2011-06
Volume
43
Issue
6
Pages
974-981
ISSN
0195-9131 (ISSN-L)
DOI
10.1249/mss.0b013e31820607a3
OpenAlex
W1976805840
Cited by
347
References
42
Citations by year
2026: 8 · 2025: 17 · 2024: 14 · 2023: 11 · 2022: 28 · 2021: 25 · 2020: 36 · 2019: 22 · 2018: 36 · 2017: 27 · 2016: 23 · 2015: 33 · 2014: 24 · 2013: 16 · 2012: 19
FWCI
9.22
Type
journal article
Language
en
Open access
closed
Locations
  • Medicine & Science in Sports & Exercise (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiomyopathy and Myosin Studies
Keywords
right ventricular remodeling, endurance athletes, end-systolic wall stress, exercise-induced cardiac remodeling, right ventricle, left ventricle, pulmonary hypertension, training load, cardiac magnetic resonance, exercise echocardiography, pulmonary artery pressure, right ventricular mass, wall thickening, Laplace law, athlete's heart
MeSH terms
Adult, Physical Exertion, Female, Heart Ventricles, Humans, Male, Oxygen Consumption, Stroke Volume, Systole, Exercise, Case-Control Studies, Ventricular Function, Left, Ventricular Function, Right, Ultrasonography, Doppler, Magnetic Resonance Imaging, Cine, Ventricular Remodeling, Athletes

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review