The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Disproportionate Exercise Load and Remodeling of the Athlete's Right Ventricle
Abstract
Purpose There is evolving evidence that intense exercise may place a disproportionate load on the right ventricle (RV) when compared with the left ventricle (LV) of the heart. Using a novel method of estimating end-systolic wall stress (ES-σ), we compared the RV and LV during exercise and assessed whether this influenced chronic ventricular remodeling in athletes. Methods For this study, 39 endurance athletes (EA) and 14 nonathletes (NA) underwent resting cardiac magnetic resonance (CMR), maximal oxygen uptake (VO2), and exercise echocardiography studies. LV and RV end-systolic wall stress (ES-σ) were calculated using the Laplace relation (ES-σ = Pr/(2h)). Ventricular size and wall thickness were determined by CMR; invasive and Doppler echo estimates were used to measure systemic and pulmonary ventricular pressures, respectively; and stroke volume was quantified by Doppler echocardiography and used to calculate changes in ventricular geometry during exercise. Results In EA, compared with NA, resting CMR measures showed greater RV than LV remodeling. The ratios RV ESV/LV ESV (1.40 ± 0.23 vs 1.26 ± 0.12, P = 0.007) and RV mass/LV mass (0.29 ± 0.04 vs 0.25 ± 0.03, P = 0.012) were greater in EA than in NA. RVES-σ was lower at rest than LVES-σ (143 ± 44 vs 252 ± 49 kdyn · cm, P Conclusions Exercise induces a relative increase in RVES-σ which exceeds LVES-σ. In athletes, greater RV enlargement and greater wall thickening may be a product of this disproportionate load excess.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It has been demonstrated that ventricular load increases with exercise intensity and is greater for the RV than the LV, 29”
From Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes (2012) · cites this paper as [29]
In the citing paper
“The considerable increases in pulmonary pressures demonstrated in trained athletes during intense exercise 29,30,34 suggest a similar physiological stress, albeit only transient.”
From Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes (2012) · cites this paper as [29]
In the citing paper
“During maximal exercise of short duration, we have previously demonstrated that the RV is placed under greater haemodynamic stress than the LV 29”
From Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes (2012) · cites this paper as [29]
Citations
Cites
STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT
Martin Bland, J., & Altman, D. (1986) · The Lancet · doi:10.1016/s0140-6736(86)90837-8 · Cited by 47,965
Beckett, A. H., Rowland, M., & TURNER, P. (1965) · The Lancet · doi:10.1016/s0140-6736(65)91037-8 · Cited by 16,917
Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review
Kovács, G., Berghold, A., Scheidl, S. J., & Olschewski, H. (2009) · European Respiratory Journal · doi:10.1183/09031936.00145608 · Cited by 1,053
Grothues, F., Moon, J., Bellenger, N. G., Smith, G. S., Klein, H., & Pennell, D. J. (2004) · American Heart Journal · doi:10.1016/j.ahj.2003.10.005 · Cited by 779
Scharhag, J., Schneider, G. K., Urhausen, A. J. P., Rochette, V., Kramann, B. H., & Kindermann, W. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02478-6 · Cited by 525
Direct Blood Pressure Measurement —Dynamic Response Requirements
Gardner, R. M. (1981) · Anesthesiology · doi:10.1097/00000542-198103000-00010 · Cited by 522
Neilan, T. G., Januzzi, J. L., Lee-Lewandrowski, E., Ton-Nu, T.-T., Yoerger, D. M., Jassal, D. S., Lewandrowski, K. B., Siegel, A. J., Marshall, J. E., Douglas, P. S., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.647461 · Cited by 519
Kirchhof, P., Fabritz, L., Zwiener, M., Witt, H., Schäfers, M., Zellerhoff, S., Paul, M., Athai, T., Hiller, K.-H., Baba, H. A., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.624502 · Cited by 429
Interventricular Mechanical Asynchrony in Pulmonary Arterial Hypertension
Marcus, J. T., Gan, C. T., Zwanenburg, J. J. M., Boonstra, A., Allaart, C. P., Götte, M., & Noordegraaf, A. V. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.10.041 · Cited by 408
Heidbüchel, H. (2003) · European Heart Journal · doi:10.1016/s0195-668x(03)00282-3 · Cited by 395
Self-citation
Cited by
Sorted by citations
Towbin, J. A., McKenna, W. J., Abrams, D. J., Ackerman, M. J., Calkins, H. G., Darrieux, F., Daubert, J. P., de Chillou, C., DePasquale, E. C., Desai, M. Y., et al. (2019) · Heart Rhythm · doi:10.1016/j.hrthm.2019.05.007 · Cited by 883
Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes
La Gerche, A., Burns, A. T., Mooney, D. J., Inder, W. J., Taylor, A. J., Bogaert, J., MacIsaac, A. I., Heidbüchel, H., & Prior, D. L. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehr397 · Cited by 776
Self-citationArrhythmogenic Right Ventricular Cardiomyopathy
Corrado, D., Link, M. S., & Calkins, H. G. (2017) · New England Journal of Medicine · doi:10.1056/nejmra1509267 · Cited by 756
Echocardiography in Pulmonary Arterial Hypertension: from Diagnosis to Prognosis
Bossone, E., D’Andrea, A., D’Alto, M., Citro, R., Argiento, P., Ferrara, F., Cittadini, A., Rubenfire, M., & Naeije, R. (2012) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2012.10.009 · Cited by 476
Franklin, B. A., Thompson, P. D., Al-Zaiti, S. S., Albert, C. M., Hivert, M.-F., Levine, B. D., Lobelo, F., Madan, K., Sharrief, A. Z., Eijsvogels, T. M. H., et al. (2020) · Circulation · doi:10.1161/cir.0000000000000749 · Cited by 410
Pelliccia, A., Caselli, S., Sharma, S., Basso, C., Bax, J. J., Corrado, D., D’Andrea, A., D’Ascenzi, F., Paolo, F. M. D., Edvardsen, T., et al. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx532 · Cited by 380
Self-citationCardiac Remodeling in Response to 1 Year of Intensive Endurance Training
Arbab‐Zadeh, A., Perhonen, M. A., Howden, E. J., Peshock, R. M., Zhang, R., Adams-Huet, B., Haykowsky, M. J., & Levine, B. D. (2014) · Circulation · doi:10.1161/circulationaha.114.010775 · Cited by 365
Utomi, V., Oxborough, D., Whyte, G. P., Somauroo, J. D., Sharma, S., Shave, R., Atkinson, G., & George, K. (2013) · Heart · doi:10.1136/heartjnl-2012-303465 · Cited by 273
Gerche, A. L., Claessen, G., Bruaene, A. V. D., Pattyn, N., Cleemput, J. V., Gewillig, M. H. M. L., Bogaert, J. G., Dymarkowski, S., Claus, P., & Heidbüchel, H. (2012) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.112.980037 · Cited by 266
Self-citationGalderisi, M., Cardim, N. M., D’Andrea, A., Bruder, O., Cosyns, B., Davin, L., Donal, E., Edvardsen, T., Freitas, A., Habib, G., et al. (2015) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeu323 · Cited by 263
Are There Deleterious Cardiac Effects of Acute and Chronic Endurance Exercise?
Eijsvogels, T. M. H., Fernández, A. B., & Thompson, P. D. (2015) · Physiological Reviews · doi:10.1152/physrev.00029.2014 · Cited by 236
Exercise and cardiovascular risk in patients with hypertension
Sharman, J. E., La Gerche, A., & Coombes, J. S. (2015) · American Journal of Hypertension · doi:10.1093/ajh/hpu191 · Cited by 224
Gerche, A. L., Claessen, G., Dymarkowski, S., Voigt, J., Buck, F. D., Vanhees, L., Droogné, W., Cleemput, J. V., Claus, P., & Heidbüchel, H. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv202 · Cited by 209
Self-citationPrior, D., & Gerche, A. L. (2012) · Heart · doi:10.1136/heartjnl-2011-301329 · Cited by 196
Self-citationExercise-Induced Cardiovascular Adaptations and Approach to Exercise and Cardiovascular Disease
Martinez, M. W., Kim, J. H., Shah, A. B., Phelan, D. M. J., Emery, M. S., Wasfy, M. M., Fernández, A. B., Bunch, T. J., Dean, P. N., Danielian, A., et al. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.08.003 · Cited by 225
Pulmonary Circulation at Exercise
Naeije, R., & Chesler, N. C. (2012) · Comprehensive physiology · doi:10.1002/cphy.c100091 · Cited by 190
Myocardial fibrosis in athletes.
van de Schoor, F. R., Aengevaeren, V. L., Hopman, M. T. E., Oxborough, D. L., George, K. P., Thompson, P. D., & Eijsvogels, T. M. H. (2016) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2016.07.012 · Cited by 168
Dilatation and Dysfunction of the Right Ventricle Immediately After Ultraendurance Exercise
Oxborough, D., Shave, R., Warburton, D. E. R., Williams, K., Oxborough, A., Charlesworth, S. A., Foulds, H. J. A., Hoffman, M. D., Birch, K. M., & George, K. (2011) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.110.961938 · Cited by 164
The Right Ventricle of the Endurance Athlete: The Relationship between Morphology and Deformation
Oxborough, D., Sharma, S., Shave, R., Whyte, G. P., Birch, K. M., Artis, N. J., Batterham, A. M., & George, K. (2011) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2011.11.017 · Cited by 160
Ventricular arrhythmias associated with long-term endurance sports: what is the evidence?
Heidbüchel, H., Prior, D., & Gerche, A. L. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2012-091162 · Cited by 153
Self-citationGerche, A. L., Burns, A., D’hooge, J., MacIsaac, A. I., Heidbüchel, H., & Prior, D. (2011) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2011.11.023 · Cited by 148
Self-citationCruz, F. M., Sanz‐Rosa, D., Roche-Molina, M., García‐Prieto, J., García-Ruiz, J. M., Pizarro, G., Jiménez‐Borreguero, L. J., Torres, M., Bernad, A., Ruı́z-Cabello, J., et al. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.01.045 · Cited by 143
Right and Left Ventricular Function and Mass in Male Elite Master Athletes
Bohm, P., Schneider, G. K., Linneweber, L., Rentzsch, A., Krämer, N., Abdul‐Khaliq, H., Kindermann, W., Meyer, T., & Scharhag, J. (2016) · Circulation · doi:10.1161/circulationaha.115.020975 · Cited by 140
Exercise-Induced Cardiac Troponin Elevations: From Underlying Mechanisms to Clinical Relevance
Aengevaeren, V. L., Baggish, A. L., Chung, E. H., George, K., Kleiven, Ø., Mingels, A. M. A., Ørn, S., Shave, R., Thompson, P. D., & Eijsvogels, T. M. H. (2021) · Circulation · doi:10.1161/circulationaha.121.056208 · Cited by 150
Lie, Ø. H., Dejgaard, L. A., Saberniak, J., Rootwelt‐Norberg, C., Stokke, M. K., Edvardsen, T., & Haugaa, K. H. (2018) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2018.01.010 · Cited by 140
Howden, E. J., Perhonen, M. A., Peshock, R. M., Zhang, R., Arbab‐Zadeh, A., ADAMS-HUET, B. A., & Levine, B. D. (2015) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00092.2015 · Cited by 138
Diagnosis, pathophysiology, and management of exercise-induced arrhythmias
Guasch, E., & Mont, L. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2016.173 · Cited by 134
Can Intensive Exercise Harm the Heart?
Gerche, A. L., & Heidbüchel, H. (2014) · Circulation · doi:10.1161/circulationaha.114.008141 · Cited by 134
Self-citationGerche, A. L., Baggish, A. L., Knuuti, J. M., Prior, D., Sharma, S., Heidbüchel, H., & Thompson, P. D. (2013) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2013.06.003 · Cited by 127
Self-citationEndurance Training and V˙O2max
Montero, D., Díaz-Cañestro, C., & Lundby, C. (2015) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000640 · Cited by 126
Brosnan, M. J., Gerche, A. L., Kalman, J. M., Lo, W. D., Fallon, K. E., MacIsaac, A. I., & Prior, D. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2014.01.438 · Cited by 112
Self-citationBlood Pressure Response to Exercise and Cardiovascular Disease
Schultz, M. G., Gerche, A. L., & Sharman, J. E. (2017) · Current Hypertension Reports · doi:10.1007/s11906-017-0787-1 · Cited by 118
Potential Long-Term Health Problems Associated with Ultra-Endurance Running: A Narrative Review
Scheer, V., Tiller, N. B., Doutreleau, S., Khodaee, M., Knechtle, B., Pasternak, A. V., & Rojas‐Valverde, D. (2021) · Sports Medicine · doi:10.1007/s40279-021-01561-3 · Cited by 134
Exercise and the right ventricle: a potential Achilles’ heel
Gerche, A. L., Rakhit, D. J., & Claessen, G. (2017) · Cardiovascular Research · doi:10.1093/cvr/cvx156 · Cited by 111
The Athlete’s Heart—Challenges and Controversies
Gerche, A. L., Wasfy, M. M., Brosnan, M. J., Claessen, G., Fatkin, D., Heidbüchel, H., Baggish, A. L., & Kovacic, J. C. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2022.07.014 · Cited by 114
Self-citationThe effects of endurance exercise on the heart: panacea or poison?
Parry-Williams, G., & Sharma, S. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0354-3 · Cited by 102
Gerche, A. L., Burns, A., Taylor, A. J., MacIsaac, A. I., Heidbüchel, H., & Prior, D. (2011) · European Journal of Applied Physiology · doi:10.1007/s00421-011-2184-9 · Cited by 96
Self-citationWang, W., Orgeron, G. M., Tichnell, C., Murray, B. A., Crosson, J. E., Monfredi, O., Cadrin‐Tourigny, J., Tandri, H. S., Calkins, H. G., & James, C. A. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.118.008843 · Cited by 91
Domènech-Ximenos, B., la Garza, M. S., Prat‐González, S., Sepúlveda-Martínez, Á., Crispi, F., Duran-Fernandez, K., Perea, R. J., Bijnens, B. H., & Sitges, M. (2020) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/s12968-020-00660-w · Cited by 100
Pagourelias, E. D., Kouidi, E. J., Efthimiadis, G. K., Deligiannis, A. P., Geleris, P., & Vassilikos, V. P. (2013) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2013.07.019 · Cited by 92
The endurance athletes heart: acute stress and chronic adaptation
George, K., Whyte, G. P., Green, D. J., Oxborough, D., Shave, R., Gaze, D. C., & Somauroo, J. D. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2012-091141 · Cited by 97
Arrhythmias as Presentation of Genetic Cardiomyopathy
Laws, J. L., Lancaster, M. C., Shoemaker, M. B., Stevenson, W. G., Hung, R. R., Wells, Q. S., Brinkley, D. M., Hughes, S. G., Anderson, K. C., Roden, D. M., et al. (2022) · Circulation Research · doi:10.1161/circresaha.122.319835 · Cited by 92
D’Andrea, A., Riegler, L., Morra, S., Scarafile, R., Salerno, G., Cocchia, R., Golia, E., Martone, F., Salvo, G. D., Limongelli, G., et al. (2012) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2012.07.020 · Cited by 89
Claessen, G., Claus, P., Delcroix, M., Bogaert, J. G., Gerche, A. L., & Heidbüchel, H. (2014) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00752.2013 · Cited by 90
Self-citationThe athlete’s heart is a proarrhythmic heart, and what that means for clinical decision making
Heidbüchel, H. (2017) · EP Europace · doi:10.1093/europace/eux294 · Cited by 88
Self-citationRight Ventricular Fatigue Developing during Endurance Exercise
Claessen, G., Claus, P., Ghysels, S., Vermeersch, P., Dymarkowski, S., Gerche, A. L., & Heidbüchel, H. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000282 · Cited by 86
Self-citationD’Ascenzi, F., Pelliccia, A., Solari, M., Piu, P., Loiacono, F., Anselmi, F., Caselli, S., Focardi, M., Bonifazi, M., & Mondillo, S. (2017) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2017.06.013 · Cited by 85
Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and Function
Zandstra, T. E., Notenboom, R. G. E., Wink, J., Kiès, P., Vliegen, H. W., Egorova, A. D., Schalij, M. J., de Ruiter, M. C., & Jongbloed, M. R. M. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.665298 · Cited by 83
The dysfunctional right ventricle: the importance of multi-modality imaging
Surkova, E., Cosyns, B., Gerber, B. L., Gimelli, A., Gerche, A. L., & Marsan, N. A. (2022) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeac037 · Cited by 80
Can Intensive Exercise Harm the Heart?
Levine, B. D. (2014) · Circulation · doi:10.1161/circulationaha.114.008142 · Cited by 85
Pulmonary Arterial Hypertension: The Key Role of Echocardiography
D’Alto, M., Romeo, E., Argiento, P., Salvo, G. D., Badagliacca, R., Cirillo, A. P., Kaemmerer, H. M., Bossone, E., & Naeije, R. (2014) · Echocardiography · doi:10.1111/echo.12283 · Cited by 80
Dempsey, J. A., Gerche, A. L., & Hull, J. H. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00444.2020 · Cited by 79
Sport category is an important determinant of cardiac adaptation: an MRI study
Luijkx, T., Cramer, M. J., Prakken, N. H. J., Buckens, C. F. M., Mosterd, A., Rienks, R., BACKX, F. J. G., Mali, W. P. T. M., & Velthuis, B. K. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2011-090520 · Cited by 78
Athlete’s Heart: Is the Morganroth Hypothesis Obsolete?
Haykowsky, M. J., Samuel, T. J., Nelson, M. D., & Gerche, A. L. (2018) · Heart Lung and Circulation · doi:10.1016/j.hlc.2018.04.289 · Cited by 77
Trivedi, S. J., Claessen, G., Stefani, L. D., Flannery, D., Brown, P., Janssens, K., Elliott, A. D., Sanders, P., Kalman, J. M., Heidbüchel, H., et al. (2020) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeaa183 · Cited by 79
Self-citationStewart, G. M., Yamada, A., Haseler, L. J., Kavanagh, J. J., Chan, J. H., Koerbin, G., Wood, C., & Sabapathy, S. (2016) · The Journal of Physiology · doi:10.1113/jp271889 · Cited by 76
Heidbüchel, H., & Gerche, A. L. (2012) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s00399-012-0180-3 · Cited by 76
Self-citationSepehrkhouy, S., Gho, J. M. I. H., van Es, R., Harakaľová, M., de Jonge, N., Dooijes, D., van der Smagt, J. J., Buijsrogge, M. P., Hauer, R. N. W., Goldschmeding, R., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.03.034 · Cited by 71
A Modern Definition of the Athlete’s Heart—for Research and the Clinic
Beaudry, R. I., Haykowsky, M. J., Baggish, A. L., & Gerche, A. L. (2016) · Cardiology Clinics · doi:10.1016/j.ccl.2016.06.001 · Cited by 67
Shave, R., & Oxborough, D. (2012) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2012.01.007 · Cited by 68
Gerche, A. L., Roberts, T., & Claessen, G. (2014) · Pulmonary Circulation · doi:10.1086/677355 · Cited by 63
Chronic adaptation of atrial structure and function in elite male athletes
McClean, G., George, K., Lord, R. N., Utomi, V., Jones, N. J., Somauroo, J. D., Fletcher, S., & Oxborough, D. (2014) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeu215 · Cited by 58
Heart mechanics at high altitude: 6 days on the top of Europe
Maufrais, C., Rupp, T., Bouzat, P., Doucende, G., Vergès, S., Nottin, S., & Walther, G. (2016) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jew286 · Cited by 56
Lifelong Physical Activity Regardless of Dose Is Not Associated With Myocardial Fibrosis
Abdullah, S. M., Barkley, K. W., Bhella, P. S., Hastings, J. L., Matulevicius, S. A., Fujimoto, N., Shibata, S., Carrick‐Ranson, G., Palmer, M. D., Gandhi, N. K., et al. (2016) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.116.005511 · Cited by 56
Cornwell, W. K., Tran, T., Cerbin, L. P., Coe, G., Muralidhar, A., Hunter, K. S., Altman, N. L., Ambardekar, A. V., TOMPKINS, C. M., Zipse, M. M., et al. (2020) · The Journal of Physiology · doi:10.1113/jp279759 · Cited by 55
Right Heart Structural and Functional Remodeling in Athletes
D’Andrea, A., Gerche, A. L., Golia, E., Teske, A. J., Bossone, E., Russo, M. G., Calabrò, R., & Baggish, A. L. (2014) · Echocardiography · doi:10.1111/echo.12226 · Cited by 54
Abnormal right ventricular relaxation in pulmonary hypertension.
Murch, S. D., La Gerche, A., Roberts, T. J., Prior, D. L., MacIsaac, A. I., & Burns, A. T. (2015) · Pulmonary Circulation · doi:10.1086/681268 · Cited by 53
Self-citationWang, W., James, C. A., & Calkins, H. G. (2018) · EP Europace · doi:10.1093/europace/euy063 · Cited by 54
Echocardiography in the evaluation of athletes
Grazioli, G., Sanz, M., Montserrat, S., Vidal, B., & Sitges, M. (2015) · F1000Research · doi:10.12688/f1000research.6595.1 · Cited by 50
Acute, Exercise Dose-Dependent Impairment in Atrial Performance During an Endurance Race
la Garza, M. S., Grazioli, G. C., Bijnens, B. H., Sarvari, S. I., Guasch, E., Pajuelo, C., Brotons, D., Subirats, E., Brugada, R., Roca, E., et al. (2016) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2016.03.016 · Cited by 49
Exercise and Arrhythmogenic Right Ventricular Cardiomyopathy
Prior, D., & Gerche, A. L. (2019) · Heart Lung and Circulation · doi:10.1016/j.hlc.2019.12.007 · Cited by 52
Self-citationGalectin-3 increase in endurance athletes
Hättasch, R., Spethmann, S., de Boer, R. A., Ruifrok, W. P., Schattke, S., Wagner, M., Schroeckh, S., Durmus, T., Schimke, I., Sanad, W., et al. (2014) · European Journal of Preventive Cardiology · doi:10.1177/2047487313492069 · Cited by 46
Endurance Exercise and the Heart: Friend or Foe?
Sanchis‐Gomar, F., Pérez, L. M., Joyner, M. J., Löllgen, H., & Lucía, A. (2015) · Sports Medicine · doi:10.1007/s40279-015-0434-4 · Cited by 45
Richter, M. J., Grimminger, J., Krüger, B., Ghofrani, H. A., Mooren, F. C., Gall, H. J., Pilat, C., & Krüger, K. (2016) · Pulmonary Circulation · doi:10.1086/690553 · Cited by 48
Is Exercise Good for the Right Ventricle? Concepts for Health and Disease
Gerche, A. L., & Claessen, G. (2015) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2015.01.022 · Cited by 46
Mechanisms of atrial fibrillation in athletes: what we know and what we do not know
Guasch, E., Mont, L., & Sitges, M. (2018) · Netherlands Heart Journal · doi:10.1007/s12471-018-1080-x · Cited by 49
Long-Term Cardiac Remodeling and Arrhythmias in Nonelite Marathon Runners
Wilhelm, M., Roten, L., Tanner, H., Schmid, J., Wilhelm, I., & Saner, H. E. (2012) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2012.02.058 · Cited by 43
Exercise-Induced Cardiac Remodeling: Lessons from Humans, Horses, and Dogs
Shave, R., Howatson, G., Dickson, D., & Young, L. (2017) · Veterinary Sciences · doi:10.3390/vetsci4010009 · Cited by 40
Exercise and arrhythmic risk in TMEM43 p.S358L arrhythmogenic right ventricular cardiomyopathy
Paulin, F. L., Hodgkinson, K. A., MacLaughlan, S., Stuckless, S. N., Templeton, C., Shah, S., Bremner, H., Roberts, J. D., Young, T., Parfrey, P. S., et al. (2020) · Heart Rhythm · doi:10.1016/j.hrthm.2020.02.028 · Cited by 40
Acute and Chronic Response to Exercise in Athletes: The “Supernormal Heart”
D’Andrea, A., Formisano, T., Riegler, L., Scarafile, R., America, R., Martone, F., Maio, M. D., Russo, M. G., Bossone, E., Galderisi, M., et al. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-4307-9_2 · Cited by 40
la Garza, M. S., Rubies, C., Batlle, M., Bijnens, B. H., Mont, L., Sitges, M., & Guasch, E. (2017) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00763.2016 · Cited by 39
Training for Longevity: The Reverse J-Curve for Exercise.
O’Keefe, E. L., Torres-Acosta, N., O’Keefe, J. H., & Lavie, C. J. (2020) · PubMed Central · Cited by 36
Targets identified from exercised heart: killing multiple birds with one stone
Wang, H., Xie, Y., Guan, L., Elkin, K. B., & Xiao, J. (2021) · npj Regenerative Medicine · doi:10.1038/s41536-021-00128-0 · Cited by 40
Stewart, G. M., Yamada, A., Haseler, L. J., Kavanagh, J. J., Koerbin, G., Chan, J. H., & Sabapathy, S. (2015) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00917.2014 · Cited by 39
Athlete’s Heart Revisited: Historical, Clinical, and Molecular Perspectives
Hsieh, P. N., Shen, S., Chukwurah, M. I., Churchill, T. W., Stewart, K. M., Chung, E. H., Weiner, R. B., Li, H., & Guseh, J. S. (2025) · Circulation Research · doi:10.1161/circresaha.125.325638 · Cited by 47
Molina, C. E., Johnson, D. M., Mehel, H., Spätjens, R. L. H. M. G., Mika, D., Algalarrondo, V., Slimane, Z. H., Lechêne, P., Abi‐Gerges, N., van der Linde, H. J., et al. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.000858 · Cited by 37
Fábián, A., Ujvári, A., Tokodi, M., Lakatos, B. K., Kiss, O., Babity, M., Zámodics, M., Sydó, N., Csulak, E., Vágó, H., et al. (2022) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwac026 · Cited by 37
Foury, F., Hu, J., & Vanderstraeten, S. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4220-y · Cited by 38
Diagnosis and Significance of Pulmonary Microvascular Disease in Diabetes
Roberts, T. J., Burns, A., MacIsaac, R. J., MacIsaac, A. I., Prior, D., & Gerche, A. L. (2018) · Diabetes Care · doi:10.2337/dc17-1904 · Cited by 36
Self-citationGraziano, F., Juhász, V., Brunetti, G., Cipriani, A., Szabó, L. E., Merkely, B. P., Corrado, D., D’Ascenzi, F., Vágó, H., & Zorzi, A. (2022) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd9100347 · Cited by 36
Lee, J., Vasan, R. S., & Xanthakis, V. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.015554 · Cited by 35
The role of new echocardiographic techniques in athlete’s heart
D’Andrea, A., Bossone, E., Radmilovic, J., Caso, P., Calabrò, R., Russo, M. G., & Galderisi, M. (2015) · F1000Research · doi:10.12688/f1000research.6745.1 · Cited by 34
Gender influence on the adaptation of atrial performance to training
Sanchis, L., Sanz‐de La Garza, M., Bijnens, B., Giraldeau, G., Grazioli, G., Marin, J., Gabrielli, L., Montserrat, S., & Sitges, M. (2017) · European Journal of Sport Science · doi:10.1080/17461391.2017.1294620 · Cited by 35
Inter-individual variability in right ventricle adaptation after an endurance race
la Garza, M. S., Grazioli, G. C., Bijnens, B. H., Pajuelo, C., Brotons, D., Subirats, E., Brugada, R., Roca, E., & Sitges, M. (2015) · European Journal of Preventive Cardiology · doi:10.1177/2047487315622298 · Cited by 35
Waller, L., Krüger, K., Conrad, K. D., Weiß, A., & Alack, K. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9061689 · Cited by 34
Claeys, M., Claessen, G., Claus, P., Bosscher, R. D., Dausin, C., Voigt, J., Willems, R., Heidbüchel, H., & Gerche, A. L. (2019) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jez228 · Cited by 33
Self-citationCardiovascular Magnetic Resonance and Sport Cardiology: a Growing Role in Clinical Dilemmas
Maestrini, V., Torlasco, C., Hughes, R. K., & Moon, J. (2020) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-020-10022-7 · Cited by 39
Bruaene, A. V. D., Claessen, G., Salaets, T., & Gewillig, M. H. M. L. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.825472 · Cited by 33
Lord, R. N., Utomi, V., Oxborough, D., Curry, B. A., Brown, M., & George, K. (2018) · European Journal of Applied Physiology · doi:10.1007/s00421-018-3906-z · Cited by 35
Exercise Capacity in Young Adults Born Small for Gestational Age
Crispi, F., Rodríguez‐López, M., Bernardino, G., Sepúlveda-Martínez, Á., Prat‐González, S., Pajuelo, C., Perea, R. J., Caralt, M. T., Casu, G., Vellvé, K., et al. (2021) · JAMA Cardiology · doi:10.1001/jamacardio.2021.2537 · Cited by 31
Metadata
- Authors
- LA GERCHE, A., HEIDBÜCHEL, H., BURNS, A. T., MOONEY, D. J., TAYLOR, A. J., PFLUGER, H. B., INDER, W. J., MACISAAC, A. I., & PRIOR, D. L.
- Affiliations
- Universitair Ziekenhuis Leuven (BE)
- St Vincent's Hospital Melbourne (AU)
- Baker Heart and Diabetes Institute (AU)
- The University of Melbourne (AU)
- ORCID
- Venue
- Medicine & Science in Sports & Exercise
- Published
- 2011-06
- Volume
- 43
- Issue
- 6
- Pages
- 974-981
- ISSN
- 0195-9131 (ISSN-L)
- OpenAlex
- W1976805840
- Cited by
- 347
- References
- 42
- Citations by year
- 2026: 8 · 2025: 17 · 2024: 14 · 2023: 11 · 2022: 28 · 2021: 25 · 2020: 36 · 2019: 22 · 2018: 36 · 2017: 27 · 2016: 23 · 2015: 33 · 2014: 24 · 2013: 16 · 2012: 19
- FWCI
- 9.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Medicine & Science in Sports & Exercise (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiomyopathy and Myosin Studies
- Keywords
- right ventricular remodeling, endurance athletes, end-systolic wall stress, exercise-induced cardiac remodeling, right ventricle, left ventricle, pulmonary hypertension, training load, cardiac magnetic resonance, exercise echocardiography, pulmonary artery pressure, right ventricular mass, wall thickening, Laplace law, athlete's heart
- MeSH terms
- Adult, Physical Exertion, Female, Heart Ventricles, Humans, Male, Oxygen Consumption, Stroke Volume, Systole, Exercise, Case-Control Studies, Ventricular Function, Left, Ventricular Function, Right, Ultrasonography, Doppler, Magnetic Resonance Imaging, Cine, Ventricular Remodeling, Athletes
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
