Cited by 196Acute Myocardial Infarction ResearchHealthcare Systems and Public HealthCoronary Interventions and Diagnostics

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Trends in Acute Myocardial Infarction Incidence and Mortality Over 30 Years in Japan: Report From the MIYAGI-AMI Registry Study

Takii, Toru, Yasuda, Satoshi, Takahashi, Jun, Ito, Kenta, Shiba, Nobuyuki, Shirato, Kunio, Shimokawa, Hiroaki, on behalf of the MIYAGI-AMI Study Investigators·2010·Circulation Journal

DOI 10.1253/circj.cj-09-0619

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Abstract

BACKGROUND: Worldwide, the rate of aging is highest in Japan, especially the female population. To explore the trends for acute myocardial infarction (AMI) in Japan, the MIYAGI-AMI Registry Study has been conducted for 30 years since 1979, whereby all AMI patients in the Miyagi prefecture are prospectively registered. METHODS AND RESULTS: In 1979-2008, 22,551 AMI patients (male/female 16,238/6,313) were registered from 43 hospitals. The age-adjusted incidence of AMI (/100,000persons/year) increased from 7.4 in 1979 to 27.0 in 2008 (P<0.001). Although control of coronary risk factors remained insufficient, the rates of ambulance use and primary percutaneous coronary intervention (PCI) have increased, and the overall in-hospital mortality (age-adjusted) has decreased from 20.0% in 1979 to 7.8% in 2008 (P<0.0001). However, the in-hospital mortality remains relatively higher in female than in male patients (12.2% vs 6.3% in 2008). Female patients were characterized by higher age and lower PCI rate. CONCLUSIONS: The MIYAGI-AMI Registry Study demonstrates the steady trend of an increasing incidence, but decreasing mortality, for AMI in Japan over the past 30 years, although the female population still remains at higher risk for in-hospital death, despite improvements in the use of ambulances and primary PCI. (Circ J 2010; 74: 93 - 100).

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Additional file 1 of Protective effect of the Impella on the left ventricular function after acute broad anterior wall ST elevation myocardial infarctions with cardiogenic shock: cardiovascular magnetic resonance imaging strain analysis
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Authors: Takii, T., Yasuda, S., Takahashi, J., Ito, K., Shiba, N., Shirato, K., Shimokawa, H., & on behalf of the MIYAGI-AMI Study Investigators
Affiliations: Tohoku University (JP)
ORCID: Takii, Toru
Yasuda, Satoshi
Takahashi, Jun
Ito, Kenta
Shimokawa, Hiroaki
Venue: Circulation Journal
Publisher: Japanese Circulation Society
Published: 2010
Volume: 74
Issue: 1
Pages: 93-100
ISSN: 1346-9843 (ISSN-L)
1347-4820
DOI: 10.1253/circj.cj-09-0619
OpenAlex: W2076952618
Cited by: 196
References: 32
Citations by year: 2026: 2 · 2025: 6 · 2024: 6 · 2023: 8 · 2022: 7 · 2021: 19 · 2020: 11 · 2019: 16 · 2018: 11 · 2017: 18 · 2016: 18 · 2015: 23 · 2014: 12 · 2013: 15 · 2012: 11
FWCI: 5.20
Type: journal article
Language: en
Open access: closed
Locations: Circulation Journal (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Coronary Interventions and Diagnostics
Keywords: acute myocardial infarction, incidence trends, in-hospital mortality, sex differences in mortality, primary percutaneous coronary intervention, ambulance use, population aging, Miyagi Prefecture
MeSH terms: Adult, Aged, Aged, 80 and over, Female, Humans, Japan, Male, Middle Aged, Myocardial Infarction, Prospective Studies, Registries, Retrospective Studies, Risk Factors, Sex Characteristics, Incidence, Hospital Mortality

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Trends in Acute Myocardial Infarction Incidence and Mortality Over 30 Years in Japan: Report From the MIYAGI-AMI Registry Study

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