Shimokawa, Hiroaki

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Ridker, P. M., Everett, B. M., Thuren, T., MacFadyen, J. G., Chang, W. H., Ballantyne, C., Fonseca, F., Nicolau, J., Koenig, W., Anker, S. D., et al. (2017) · New England Journal of Medicine

Atherosclerosis and Cardiovascular DiseasesLipoproteins and Cardiovascular Health

Cited by 9,482

Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

Ridker, P. M., MacFadyen, J. G., Thuren, T., Everett, B. M., Libby, P., Glynn, R. J., Ridker, P., Lorenzatti, A., Krum, H., Varigos, J., et al. (2017) · The Lancet

Inflammasome and immune disordersInflammatory Biomarkers in Disease Prognosis

Cited by 1,344

Endothelial dysfunction and vascular disease - a 30th anniversary update

Vanhoutte, P. M., Shimokawa, H., Feletou, M., & Tang, E. H. C. (2017) · Acta Physiologica

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 937

JCS 2018 Guideline on Diagnosis and Treatment of Acute Coronary Syndrome

Kimura, K., Kimura, T., Ishihara, M., Nakagawa, Y., Nakao, K., Miyauchi, K., Sakamoto, T., Tsujita, K., Hagiwara, N., Miyazaki, S., et al. (2019) · Circulation Journal

Acute Myocardial Infarction ResearchCoronary Interventions and Diagnostics

Cited by 565

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

Kubota, T., Kubota, N., Kumagai, H., Yamaguchi, S., Kozono, H., Takahashi, T., Inoue, M., Itoh, S., Takamoto, I., Sasako, T., et al. (2011) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 435

Fulminant Versus Acute Nonfulminant Myocarditis in Patients With Left Ventricular Systolic Dysfunction

Ammirati, E., Veronese, G., Brambatti, M., Merlo, M., Cipriani, M., Potena, L., Sormani, P., Aoki, T., Sugimura, K., Sawamura, A., et al. (2019) · Journal of the American College of Cardiology

Viral Infections and Immunology ResearchTakotsubo Cardiomyopathy and Associated Phenomena

Cited by 279

Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE)

Persidsky, Y., Heilman, D., Haorah, J., Zelivyanskaya, M., Persidsky, R., Weber, G. A., Shimokawa, H., Kaibuchi, K., & Ikezu, T. (2006) · Blood

Barrier Structure and Function StudiesHIV Research and Treatment

Cited by 200

Trends in Acute Myocardial Infarction Incidence and Mortality Over 30 Years in Japan: Report From the MIYAGI-AMI Registry Study

Takii, T., Yasuda, S., Takahashi, J., Ito, K., Shiba, N., Shirato, K., Shimokawa, H., & on behalf of the MIYAGI-AMI Study Investigators (2010) · Circulation Journal

Acute Myocardial Infarction ResearchHealthcare Systems and Public Health

Cited by 196

A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk

Williams, S. A., Ostroff, R., Hinterberg, M. A., Coresh, J., Ballantyne, C. M., Matsushita, K., Mueller, C. E., Walter, J., Jonasson, C., Holman, R. R., et al. (2022) · Science Translational Medicine

Lipoproteins and Cardiovascular HealthCardiovascular Health and Risk Factors

Cited by 97

Vasculoprotective Roles of Neuronal Nitric Oxide Synthase

Morishita, T., Tsutsui, M., Shimokawa, H., Horiuchi, M., Tanimoto, A., Suda, O., Tasaki, H., Huang, P. L., Sasaguri, Y., Yanagihara, N., et al. (2002) · The FASEB Journal

Nitric Oxide and Endothelin EffectsCardiovascular, Neuropeptides, and Oxidative Stress Research

Cited by 94

The first multicenter, randomized, controlled trial of home telemonitoring for Japanese patients with heart failure: home telemonitoring study for patients with heart failure (HOMES-HF)

On behalf of the HOMES-HF study investigators, Kotooka, N., Kitakaze, M., Nagashima, K., Asaka, M., Kinugasa, Y., Nochioka, K., Mizuno, A., Nagatomo, D., Mine, D., et al. (2018) · Heart and Vessels

Heart Failure Treatment and ManagementTelemedicine and Telehealth Implementation

Cited by 66

A Pilot Study of Whole-Brain Low-Intensity Pulsed Ultrasound Therapy for Early Stage of Alzheimer’s Disease (LIPUS-AD): A Randomized, Double-Blind, Placebo-Controlled Trial

Shimokawa, H., Shindo, T., Ishiki, A., Tomita, N., Ichijyo, S., Watanabe, T., Nakata, T., Eguchi, K., Kikuchi, Y., Shiroto, T., et al. (2022) · The Tohoku Journal of Experimental Medicine

Ultrasound and Hyperthermia ApplicationsAlzheimer's disease research and treatments

Cited by 51

Post‐discharge arrhythmic risk stratification of patients with acute myocarditis and life‐threatening ventricular tachyarrhythmias

Gentile, P., Merlo, M., Peretto, G., Ammirati, E., Sala, S., Della Bella, P., Aquaro, G. D., Imazio, M., Potena, L., Campodonico, J., et al. (2021) · European Journal of Heart Failure

Viral Infections and Immunology ResearchCardiovascular Effects of Exercise

Cited by 46

Structural abnormality of the hippocampus associated with depressive symptoms in heart failure rats

Suzuki, H., Sumiyoshi, A., Matsumoto, Y., Duffy, B. A., Yoshikawa, T., Lythgoe, M. F., Yanai, K., Taki, Y., Kawashima, R., & Shimokawa, H. (2015) · NeuroImage

Treatment of Major DepressionNeurogenesis and neuroplasticity mechanisms

Cited by 35

Pivotal trial of low-intensity pulsed ultrasound therapy for early Alzheimer's disease: Rationale and design

Shimokawa, H., Akishita, M., Ihara, M., Teramukai, S., Ishiki, A., Nagai, Y., & Fukushima, M. (2025) · Journal of Alzheimer's Disease Reports

Alzheimer's disease research and treatmentsUltrasound and Hyperthermia Applications

Cited by 3

Baseline characteristics of patients with early Alzheimer's disease enrolled in the pivotal trial of low-intensity pulsed ultrasound (LIPUS-AD)

Shimokawa, H., Akishita, M., Asada, T., Katayama, S., Hattori, Y., Yakushiji, Y., Taki, Y., Murai, H., Boku, Y., Tsujimoto, M., et al. (2025) · Journal of Alzheimer's Disease Reports

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 0