The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Wobble base-pairing slows in vivo translation elongation in metazoans
Open accessAbstract
In the universal genetic code, most amino acids can be encoded by multiple trinucleotide codons, and the choice among available codons can influence position-specific translation elongation rates. By using sequence-based ribosome profiling, we obtained transcriptome-wide profiles of in vivo ribosome occupancy as a function of codon identity in Caenorhabditis elegans and human cells. Particularly striking in these profiles was a universal trend of higher ribosome occupancy for codons translated via G:U wobble base-pairing compared with synonymous codons that pair with the same tRNA family using G:C base-pairing. These data support a model in which ribosomal translocation is slowed at wobble codon positions.
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Cox, J., & Mann, M. (2008) · Nature Biotechnology · doi:10.1038/nbt.1511 · Cited by 14,855
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
Ingolia, N. T., Ghaemmaghami, S., Newman, J. R. S., & Weissman, J. S. (2009) · Science · doi:10.1126/science.1168978 · Cited by 3,853
Cited by
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Mauro, V. P., & Chappell, S. A. (2014) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2014.09.003 · Cited by 343
Silent Substitutions Predictably Alter Translation Elongation Rates and Protein Folding Efficiencies
Spencer, P. S., Siller, E., Anderson, J. F., & Barral, J. M. (2012) · Journal of Molecular Biology · doi:10.1016/j.jmb.2012.06.010 · Cited by 278
A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis
Laguesse, S., Creppe, C., Nedialkova, D. D., Prévot, P.-P., Borgs, L., Huysseune, S., Franco, B., Duysens, G., Krusy, N., Lee, G., et al. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.11.005 · Cited by 228
Multiple roles of the coding sequence 5′ end in gene expression regulation
Tuller, T., & Zur, H. (2015) · Nucleic Acids Research · doi:10.1093/nar/gku1313 · Cited by 206
Metadata
- Authors
- Stadler, M., & Fire, A.
- Venue
- RNA
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2011-11-01
- Volume
- 17
- Issue
- 12
- Pages
- 2063-2073
- ISSN
- 1355-8382 (ISSN-L)
- 1469-9001
- OpenAlex
- W2161616648
- Cited by
- 187
- References
- 2
- FWCI
- 4.94
- Type
- journal article
- Language
- en
- Open access
- bronze
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