New perspectives in the treatment of body dysmorphic disorder
Open accessAbstract
Body dysmorphic disorder (BDD) is a disabling illness with a high worldwide prevalence. Patients demonstrate a debilitating preoccupation with one or more perceived defects, often marked by poor insight or delusional convictions. Multiple studies have suggested that selective serotonin reuptake inhibitors and various cognitive behavioral therapy modalities are effective first-line treatments in decreasing BDD severity, relieving depressive symptoms, restoring insight, and increasing quality of life. Selective serotonin reuptake inhibitors have also recently been shown to be effective for relapse prevention. This review provides a comprehensive summary of the current understanding of BDD, including its clinical features, epidemiology, genetics, and current treatment modalities. Additional research is needed to fully elucidate the relationship between BDD and comorbid illnesses such as obsessive–compulsive-related disorders and depression and to develop therapies for refractory patients and those who have contraindications for pharmacological intervention.
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SSRIs including fluoxetine, sertraline, and escitalopram significantly reduce BDD-related obsessive thoughts and compulsive behaviors.
“SSRIs, including fluoxetine, sertraline, and escitalopram, have been demonstrated to significantly reduce BDD-related obsessive thoughts and compulsive behaviors [124].”
From The Impact of Social Media & Technology on Child and Adolescent Mental Health (2025) · cites this paper as [124]
The Treatment section identifies fluoxetine and escitalopram as serotonin reuptake inhibitors used for BDD and reports reduced BDD symptoms with escitalopram treatment. The copy does not identify sertraline or demonstrate a significant reduction specifically in BDD-related obsessive thoughts and compulsive behaviors; its discussion of improved repetitive behaviors with fluoxetine concerns adults with autism, not BDD. No page numbers are available in the indexed passages. (LLM, conf=0.86)
Experimental — accuracy not yet measuredBDD-ben a szerotonin-visszavételt gátló antidepresszívumok (SSRI) az elsőként választandó gyógyszerek.
“BDD-ben a szerotonin-visszavételt gátló antidepresszívumok (röviden, angolul: SSRI) az els ő ként választandó gyógyszerek (Krebs, Fernández de la Cruz és Mataix-Cols, 2017; Hong, Nezgovorova és Hollander, 2018; Hong, Nezgovorova, Uzunova, Schlussel és Hollander, 2019).”
From A testdiszmorfiás zavar pszichológiai vonatkozásai (2023) · cites this paper as Hong, Nezgovorova és Hollander, 2018
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- Authors
- Hong, K., Nezgovorova, V., & Hollander, E.
- Affiliations
- Albert Einstein College of Medicine (US)
- Corresponding author
- Hollander, Eric
- Venue
- F1000Research
- Publisher
- F1000 Research Ltd
- Published
- 2018-03-23
- Volume
- 7
- Pages
- 361
- ISSN
- 2046-1402 (ISSN-L)
- PMC
- PMC5871801
- OpenAlex
- W2792573455
- Cited by
- 31
- References
- 79
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 3 · 2023: 3 · 2022: 5 · 2021: 6 · 2020: 3 · 2019: 3 · 2018: 1
- FWCI
- 0.55
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- F1000Research (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Institutes of Health (UL1TR001073)
- National Center for Advancing Translational Sciences
- Topics
- Social Sciences › Psychology › Clinical Psychology › Body Image and Dysmorphia Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Keywords
- body dysmorphic disorder, treatment, selective serotonin reuptake inhibitors, cognitive behavioral therapy, insight, relapse prevention, depression, obsessive-compulsive and related disorders, comorbidities
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