Cited by 129Body Image and Dysmorphia StudiesDigital Mental Health InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Therapist guided Internet based cognitive behavioural therapy for body dysmorphic disorder: Single blind randomised controlled trial

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Enander, Jesper, Andersson, Erik, Mataix-Cols, David, Lichtenstein, Linn, Alström, Katarina, Andersson, Gerhard, Ljótsson, Brjánn, Rück, Christian·2016·BMJ

Abstract

OBJECTIVES: To evaluate the efficacy of therapist guided internet based cognitive behavioural therapy (CBT) programme for body dysmorphic disorder (BDD-NET) compared with online supportive therapy. DESIGN: A 12 week single blind parallel group randomised controlled trial. SETTING: Academic medical centre. PARTICIPANTS: 94 self referred adult outpatients with a diagnosis of body dysmorphic disorder and a modified Yale-Brown obsessive compulsive scale (BDD-YBOCS) score of ≥ 20. Concurrent psychotropic drug treatment was permitted if the dose had been stable for at least two months before enrolment and remained unchanged during the trial. INTERVENTIONS: Participants received either BDD-NET (n=47) or supportive therapy (n=47) delivered via the internet for 12 weeks. MAIN OUTCOME MEASURES: The primary outcome was the BDD-YBOCS score after treatment and follow-up (three and six months from baseline) as evaluated by a masked assessor. Responder status was defined as a ≥ 30% reduction in symptoms on the scale. Secondary outcomes were measures of depression (MADRS-S), global functioning (GAF), clinical global improvement (CGI-I), and quality of life (EQ5D). The six month follow-up time and all outcomes other than BDD-YBOCS and MADRS-S at 3 months were not pre-specified in the registration at clinicaltrials.gov because of an administrative error but were included in the original trial protocol approved by the regional ethics committee before the start of the trial. RESULTS: BDD-NET was superior to supportive therapy and was associated with significant improvements in severity of symptoms of body dysmorphic disorder (BDD-YBOCS group difference -7.1 points, 95% confidence interval -9.8 to -4.4), depression (MADRS-S group difference -4.5 points, -7.5 to -1.4), and other secondary measures. At follow-up, 56% of those receiving BDD-NET were classed as responders, compared with 13% receiving supportive therapy. The number needed to treat was 2.34 (1.71 to 4.35). Self reported satisfaction was high. CONCLUSIONS: CBT can be delivered safely via the internet to patients with body dysmorphic disorder. BDD-NET has the potential to increase access to evidence based psychiatric care for this mental disorder, in line with NICE priority recommendations. It could be particularly useful in a stepped care approach, in which general practitioner or other mental health professionals can offer treatment to people with mild to moderate symptoms at low risk of suicide.Trial registration ClinicalTrials.gov ID: NCT02010619.

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Authors
Enander, J., Andersson, E., Mataix-Cols, D., Lichtenstein, L., Alström, K., Andersson, G., Ljótsson, B., & Rück, C.
Affiliations
  • Karolinska Institutet (SE)
  • Linköping University (SE)
Corresponding author
Enander, Jesper
Venue
BMJ
Publisher
BMJ
Published
2016-02-02
Volume
352
Pages
i241
ISSN
1756-1833 (ISSN-L)
OpenAlex
W2253482453
Cited by
129
References
50
Citations by year
2026: 7 · 2025: 10 · 2024: 19 · 2023: 13 · 2022: 13 · 2021: 13 · 2020: 13 · 2019: 11 · 2018: 14 · 2017: 12 · 2016: 4
FWCI
18.28
Type
journal article
Language
en
Open access
Locations
  • BMJ (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • KTH Publication Database DiVA (KTH Royal Institute of Technology) (submittedVersion, other-oa)
  • HighWire Press Open Archive (submittedVersion)
Funders
  • Karolinska Institutet
  • Stockholms Läns Landsting
  • Vetenskapsrådet (K2013-61X-22168-01-3)
  • Svenska Läkaresällskapet (SLS3B4451)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Body Image and Dysmorphia Studies
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
body dysmorphic disorder, internet-based cognitive behavioral therapy, supportive therapy, depression, quality of life, stepped care, access to mental health care, number needed to treat
MeSH terms
Adolescent, Adult, Aged, Depression, Female, Humans, Male, Middle Aged, Quality of Life, Remission Induction, Social Support, Cognitive Behavioral Therapy, Single-Blind Method, Treatment Outcome, Internet, Directive Counseling, Young Adult, Body Dysmorphic Disorders

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