The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Radioprotectors in Radiotherapy
Open accessAbstract
Ionizing radiation induces a wide variety of modifications to purine and pyrimidine residues. The exocyclic methyl group of thymine does not escape oxidative damage. Any 5-hydroperoxymethyluracil produced is spontaneously decomposed to form 5-formyluracil (5-foU) and 5-hydroxymethyluracil. The yield of 5-foU by ionizing radiation is roughly the same as that of 8-oxoguanine. 5-foU is a potential mutagenic damage in vitro and in vivo. Mammalian cells have an activity that removes 5-foU from X-irradiated DNA. Furthermore, the Nth, Nei and MutM proteins of E. coli have DNA glycosylase/AP lyase activities that recognize and remove 5-foU in DNA. The mutation frequency of 5-foU-containing plasmid increases when replicated in E. coli nthneimutMalkA. Single mutations in the nth, nei or mutM gene do not affect the mutation frequency. Therefore, these gene products are likely backup enzymes used to repair 5-foU in DNA. Furthermore, the human hNTH1 enzyme, a homologue of E. coli Nth, is found to have similar DNA glycosylase activity to that of the Nth protein.
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Free radicals in biology and medicine
(1991) · General Pharmacology: The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178
Fridovich (1978) · doi:10.1126/science.210504 · Cited by 3,329
Needleman, P., Truk, J., Jakschik, B. A., Morrison, A. R., & Lefkowith, J. B. (1986) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.55.070186.000441 · Cited by 1,807
Biochemistry of metallothionein
Kaegi, J. H. R., & Schaeffer, A. (1988) · Biochemistry · doi:10.1021/bi00423a001 · Cited by 1,225
Angiotensin-Converting Enzyme Inhibitors
Brown, N. J., & Vaughan, D. E. (1998) · Circulation · doi:10.1161/01.cir.97.14.1411 · Cited by 958
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
Tanaka, H., Arakawa, H., Yamaguchi, T., Shiraishi, K., Fukuda, S., Matsui, K., Takei, Y., & Nakamura, Y. (2000) · Nature · doi:10.1038/35003506 · Cited by 904
Melatonin: A peroxyl radical scavenger more effective than vitamin E
Pieri, C., Marra, M., Moroni, F., Recchioni, R., & Marcheselli, F. (1994) · Life Sciences · doi:10.1016/0024-3205(94)00666-0 · Cited by 735
Radioprotectors and anticarcinogens
Anticarcinogens, Nygaard, O. F., Simic, M. G., & Hauber, J. N. (1983) · Academic Press eBooks · Cited by 610
The Radiation Chemistry of Water
(1971) · Physical Chemistry · doi:10.1016/b978-0-12-221650-3.x5001-8 · Cited by 563
Interleukin 1 is a radioprotector.
Neta, R., Douches, S., & Oppenheim, J. J. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.136.7.2483 · Cited by 371
Cited by
Ferulic Acid: Therapeutic Potential Through Its Antioxidant Property
Srinivasan, M., Sudheer, A. R., & Menon, V. P. (2007) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.40.92 · Cited by 1,075
Protection from radiation-induced pneumonitis using cerium oxide nanoparticles
Colon, J., Herrera, L., Smith, J., Patil, S., Komanski, C., Kupelian, P., Seal, S., Jenkins, D. W., & Baker, C. H. (2009) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2008.10.003 · Cited by 295
MATSUU, M., SHICHIJO, K., OKAICHI, K., WEN, C. Y., FUKUDA, E., NAKASHIMA, M., NAKAYAMA, T., SHIRAHATA, S., TOKUMARU, S., & SEKINE, I. (2003) · Journal of Radiation Research · doi:10.1269/jrr.44.111 · Cited by 38
Metadata
- Authors
- NAIR, C. K. K., PARIDA, D. K., & NOMURA, T.
- Venue
- Journal of Radiation Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2001
- Volume
- 42
- Issue
- 1
- Pages
- 21-37
- ISSN
- 0449-3060 (ISSN-L)
- OpenAlex
- W2170124346
- Cited by
- 466
- References
- 48
- FWCI
- 8.98
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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