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Cited by 243

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Rutin-enhanced Antibacterial Activities of Flavonoids against Bacillus cereus and Salmonella enteritidis

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ARIMA, Hidetoshi, ASHIDA, Hitoshi, DANNO, Gen-ichi·2002·Bioscience, Biotechnology, and Biochemistry

Abstract

The antibacterial activities of flavonoids were found by the paper disk method to be enhanced by combining or mixing them. The combinations of quercetin and quercitrin, quercetin and morin, and quercetin and rutin were much more active than either flavonoid alone. Although rutin did not show activity in itself, the antibacterial activities of quercetin and morin were enhanced in the presence of rutin. The antibacterial activities of flavonoids, in combination with morin and rutin, were evaluated, based on the minimum inhibition concentration (MIC) in a liquid culture, by using Salmonella enteritidis and Bacillus cereus as the test bacteria. The activities of galangin, kaempherol, myricetin and fisetin were each enhanced in the presence of rutin when S. enteritidis was used as the test bacterium. The MIC value for kaempherol was markedly decreased by the addition of rutin. Morin inhibited DNA synthesis, and this effect was promoted by rutin at a concentration of 25 microg/ml.

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Metadata

Authors
ARIMA, H., ASHIDA, H., & DANNO, G.-I.
Venue
Bioscience, Biotechnology, and Biochemistry
Published
2002-01
Volume
66
Issue
5
Pages
1009-1014
ISSN
  • 0916-8451 (ISSN-L)
  • 1347-6947
OpenAlex
W1985378557
Cited by
243
References
1
FWCI
1.68
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Rutin-enhanced Antibacterial Activities of Flavonoids against Bacillus cereus and Salmonella enteritidis. https://app.cochat.ai/papers/10.1271/bbb.66.1009
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ARIMA, H., ASHIDA, H., & DANNO, G.-I. (2002). Rutin-enhanced Antibacterial Activities of Flavonoids against Bacillus cereus and Salmonella enteritidis. Bioscience, Biotechnology, and Biochemistry. https://doi.org/10.1271/bbb.66.1009

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