Cited by 102Antifungal resistance and susceptibilityEssential Oils and Antimicrobial ActivityPhytochemicals and Antioxidant Activities

Antifungal Activity of Phenolic Compounds Identified in Flowers from North Eastern Portugal Against Candida Species

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Alves, Carlos Tiago, Ferreira, Isabel CFR, Barros, Lillian, Silva, Sónia, Azeredo, Joana, Henriques, Mariana·2014·Future Microbiology

Abstract

AIM: To evaluate the antifungal effect of gallic acid, catechin, luteolin and quercetin, phenolic compounds identified from flowers of North Eastern Portugal, against Candida planktonic and biofilm cells. MATERIALS & METHODS: The MICs were determined in Candida planktonic cells and the effect of phenolic compounds on Candida biofilms was assessed through quantification of colony-forming units. RESULTS: MIC values demonstrated that gallic acid presented the highest effect against all Candida species. Catechin showed a similar effect against Candida albicans American Type Culture Collection (ATCC) 90028 cells. In addition, gallic acid and quercetin had demonstrated only a minimal effect against Candida species biofilms. CONCLUSION: Gallic acid affected the growth of the different planktonic Candida species in all concentrations used; still, catechin showed a similar effect against C. albicans ATCC 90028 and Candida glabrata ATCC 2001 cells. In addition, only gallic acid and quercetin demonstrated a slight effect against all Candida species biofilms.

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Crossref · 10.2217/fmb.13.147

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48 of 48 references verified0 citation errors · 0 not checkable

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  • Gallic acid from banana peel has potential antifungal activity against four studied yeast of Candida spp.

    “some reports observed that gallic acid from banana peel had potential antifungal activity against four studied yeast of Candida spp. [69–71]”

    From Banana Peels: A Waste Treasure for Human Being (2022) · cites this paper as [70]

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Authors
Alves, C. T., Ferreira, I. C., Barros, L., Silva, S., Azeredo, J., & Henriques, M.
Affiliations
  • Institute for Biotechnology and Bioengineering (PT)
  • Universidade Politécnica de Bragança (PT)
Venue
Future Microbiology
Published
2014-02
Volume
9
Issue
2
Pages
139-146
ISSN
  • 1746-0913 (ISSN-L)
  • 1746-0921
OpenAlex
W2152700797
Cited by
102
References
49
Citations by year
2026: 4 · 2025: 7 · 2024: 7 · 2023: 3 · 2022: 18 · 2021: 7 · 2020: 12 · 2019: 6 · 2018: 10 · 2017: 13 · 2016: 10 · 2015: 4 · 2014: 1
FWCI
6.54
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Future Microbiology (publishedVersion)
  • PubMed (publishedVersion)
  • Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
  • Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by-nc-nd)
Funders
  • PEst (OE/AGR/UI0690/2011)
  • FCT, POPH-QREN and FSE (SFRH/BD/72742/2010 and SFRH/BPD/4609/2008)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
Keywords
antifungal activity, phenolic compounds, Candida, Candida albicans, Candida glabrata, Candida biofilms, gallic acid, catechins, luteolin, quercetin, flowers, minimum inhibitory concentration, plant extracts
MeSH terms
Antifungal Agents, Candida, Candidiasis, Catechin, Gallic Acid, Microbial Sensitivity Tests, Phenols, Portugal, Quercetin, Biofilms, Plant Preparations, Flowers, Luteolin

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