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The Effects of Sericin Cream on Wound Healing in Rats
Open accessAbstract
Sericin has good hydrophilic properties, compatibility, and biodegradation, it can be used as a wound-healing agent. We evaluated the effects of sericin on wound healing and wound size reduction using rats by generating two full-thickness skin wounds on the dorsum. Group 1 animals were treated with Betadine on left-side (control) wounds and, with 8% sericin cream on right-side (treated) wounds. Group 2, cream base (formula control) and 8% sericin cream (treated) were topically applied to left-, and right-side wounds respectively. Sericin-treated wounds had much smaller inflammatory reactions, and wound-size reduction was much greater than in the control throughout the inspection period. Mean time in days for 90% healing from sericin-treated wounds was also much less than for cream base-treated wounds. Histological examination after 15 d of treatment with 8% sericin cream revealed complete healing, no ulceration, and an increase in collagen as compared to cream base-treated wounds, which showed some ulceration and acute inflammatory exudative materials.
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Cited by
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Chen, Q., Liang, S., & Thouas, G. A. (2013) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.05.003 · Cited by 564
Effect of processing on silk‐based biomaterials: Reproducibility and biocompatibility
Wray, L. S., Hu, X., Gallego, J., Georgakoudi, I., Omenetto, F. G., Schmidt, D., & Kaplan, D. L. (2011) · Journal of Biomedical Materials Research Part B: Applied Biomaterials · doi:10.1002/jbm.b.31875 · Cited by 360
The Effect of Sericin from Various Extraction Methods on Cell Viability and Collagen Production
Aramwit, P., Kanokpanont, S., Nakpheng, T., & Srichana, T. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11052200 · Cited by 334
Self-citationPotential applications of silk sericin, a natural protein from textile industry by-products
Aramwit, P., Siritientong, T., & Srichana, T. (2012) · Waste Management & Research: The Journal for a Sustainable Circular Economy · doi:10.1177/0734242x11404733 · Cited by 320
Self-citationPadol, A., Jayakumar, K., Shridhar, N., Swamy, N. D., Swamy, N., & Mohan, K. (2011) · Toxicology International · doi:10.4103/0971-6580.75847 · Cited by 75
Metadata
- Authors
- ARAMWIT, P., & SANGCAKUL, A.
- Venue
- Bioscience, Biotechnology, and Biochemistry
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-10-23
- Volume
- 71
- Issue
- 10
- Pages
- 2473-2477
- ISSN
- 0916-8451 (ISSN-L)
- 1347-6947
- OpenAlex
- W1992039191
- Cited by
- 240
- References
- 0
- FWCI
- 4.63
- Type
- journal article
- Language
- en
- Open access
- bronze
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- ARAMWIT, P., & SANGCAKUL, A. (2007). The Effects of Sericin Cream on Wound Healing in Rats. Bioscience, Biotechnology, and Biochemistry. https://doi.org/10.1271/bbb.70243
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
