The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
The Effect of Sericin from Various Extraction Methods on Cell Viability and Collagen Production
Open accessAbstract
Silk sericin (SS) can accelerate cell proliferation and attachment; however, SS can be extracted by various methods, which result in SS exhibiting different physical and biological properties. We found that SS produced from various extraction methods has different molecular weights, zeta potential, particle size and amino acid content. The MTT assay indicated that SS from all extraction methods had no toxicity to mouse fibroblast cells at concentrations up to 40 μg/mL after 24 h incubation, but SS obtained from some extraction methods can be toxic at higher concentrations. Heat-degraded SS was the least toxic to cells and activated the highest collagen production, while urea-extracted SS showed the lowest cell viability and collagen production. SS from urea extraction was severely harmful to cells at concentrations higher than 100 μg/mL. SS from all extraction methods could still promote collagen production in a concentration-dependent manner, even at high concentrations that are toxic to cells.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Mosmann, T. (1983) · Journal of Immunological Methods · doi:10.1016/0022-1759(83)90303-4 · Cited by 56,104
Isolation of Three Main Sericin Components from the Cocoon of the Silkworm,Bombyx mori
TAKASU, Y., YAMADA, H., & TSUBOUCHI, K. (2002) · Bioscience, Biotechnology, and Biochemistry · doi:10.1271/bbb.66.2715 · Cited by 304
Terada, S., Nishimura, T., Sasaki, M., Yamada, H., & Miki, M. (2002) · Cytotechnology · doi:10.1023/a:1023993400608 · Cited by 243
The Effects of Sericin Cream on Wound Healing in Rats
ARAMWIT, P., & SANGCAKUL, A. (2007) · Bioscience, Biotechnology, and Biochemistry · doi:10.1271/bbb.70243 · Cited by 240
Self-citationSericin Enhances Attachment of Cultured Human Skin Fibroblasts
TSUBOUCHI, K., IGARASHI, Y., TAKASU, Y., & YAMADA, H. (2005) · Bioscience, Biotechnology, and Biochemistry · doi:10.1271/bbb.69.403 · Cited by 228
Inflammatory mediators in wound healing
Henry, G., & Garner, W. L. (2003) · Surgical Clinics of North America · doi:10.1016/s0039-6109(02)00200-1 · Cited by 175
Preparation of silk protein sericin as mitogenic factor for better mammalian cell culture
Terada, S., Sasaki, M., Yanagihara, K., & Yamada, H. (2005) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.100.667 · Cited by 142
Bombyx mori silk proteins. Characterization of large polypeptides
Sprague, K. U. (1975) · Biochemistry · doi:10.1021/bi00676a008 · Cited by 139
Aramwit, P., Kanokpanont, S., De‐Eknamkul, W., Kamei, K., & Srichana, T. (2009) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856209x453006 · Cited by 127
Self-citationDevelopment of a novel serum‐free freezing medium for mammalian cells using the silk protein sericin
Sasaki, M., Kato, Y., Yamada, H., & Terada, S. (2005) · Biotechnology and Applied Biochemistry · doi:10.1042/ba20050019 · Cited by 98
Cited by
Elastomeric biomaterials for tissue engineering
Chen, Q., Liang, S., & Thouas, G. A. (2013) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.05.003 · Cited by 564
Silk biomaterials in wound healing and skin regeneration therapeutics: From bench to bedside
Chouhan, D., & Mandal, B. B. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.11.050 · Cited by 348
Potential applications of silk sericin, a natural protein from textile industry by-products
Aramwit, P., Siritientong, T., & Srichana, T. (2012) · Waste Management & Research: The Journal for a Sustainable Circular Economy · doi:10.1177/0734242x11404733 · Cited by 320
Self-citationAnimal-derived products in science and current alternatives
Duarte, A. C., Costa, E. C., Filipe, H. A. L., Saraiva, S. M., Jacinto, T., Miguel, S. P., Ribeiro, M. P., & Coutinho, P. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213428 · Cited by 117
Metadata
- Authors
- Aramwit, P., Kanokpanont, S., Nakpheng, T., & Srichana, T.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2010-05-20
- Volume
- 11
- Issue
- 5
- Pages
- 2200-2211
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2082062885
- Cited by
- 334
- References
- 12
- FWCI
- 4.03
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Effect of Sericin from Various Extraction Methods on Cell Viability and Collagen Production. https://app.cochat.ai/papers/10.3390/ijms11052200
- The paper
- Aramwit, P., Kanokpanont, S., Nakpheng, T., & Srichana, T. (2010). The Effect of Sericin from Various Extraction Methods on Cell Viability and Collagen Production. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms11052200
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
