Effects of L-Theanine on the Release of .ALPHA.-Brain Waves in Human Volunteers.
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L-テアニンは緑茶の葉中および抽出液中に含まれているアミノ酸の一種で,カフェインによる興奮を抑制することが知られている.また,ラットへのL-テアニンの経口投与により,脳内のセロトニンが減少し,カテコールアミンの増加ずることが知られている. L-テアニンは動物実験で安全なことがすでに確認されている. 筆者らはL-テアニン服用による脳波への影響について検討した結果,リラックスをもたらすことを確認した. L-テアニンの影響を不安程度の異なる精神状態で調べるため, MAS法に従って段階I(高不安域群)の4名と段階V(低不安域群)の4名の計8名の女子学生を被験者に選定した. その結果, L-テアニン200mgを含む水100ml服用によって後頭部・頭頂部にα波の出現が認められた.α波出現は服用後40分後に観測され,少なくとも2時間は持続すると考えられる.α波の出現によるリラックス作用は,段階Vの低不安域群より段階Iの高不安域群の方が優れていた. L-テアニン服用後,被験者は眠気を感じず,十分なリラックスを感じた.また,指先が暖かくなったとの体感を感じた被験者もいた. 今回の研究により, L-テアニンは新しいタイプの添加物として食品や飲料に応用される可能性が示唆された.今後はさまざまなL-テアニン含有食品についての効果を検討するつもりである.
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L-theanine ingestion increases alpha-band activity during rest.
“Using electroencephalographic (EEG) recordings in humans, Kobayashi et al. (12) and Juneja et al. (13) reported that activity within the alpha frequency band (8-14 Hz) increased in reaction to L-theanine ingestion when measured during a state of rest.”
From L-Theanine and Caffeine in Combination Affect Human Cognition as Evidenced by Oscillatory alpha-Band Activity and Attention Task Performance (2008) · cites this paper as [12]
l-theanine intake increases α-wave activity.
“Studies that explored brain activity have previously reported that l-theanine intake increases α-wave activity.29,30”
From Effects of <scp>l</scp> -Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study (2021) · cites this paper as [29]
When 50 mg of theanine is ingested, alpha waves appear 40 min later.
“When 50 mg of theanine is ingested, alpha waves appear 40 min later.38,39”
From Theanine maintains sleep quality in healthy young women by suppressing the increase in caffeine-induced wakefulness after sleep onset (2023) · cites this paper as [38]
L-THE intake (50-200 mg) significantly increases the pattern intensity of α-wave production in different areas of the cerebral cortex without causing drowsiness due to unchanged θ-waves.
“Several studies have shown that L-THE intake (50-200 mg) significantly increases the pattern intensity of α-wave production in the different areas of the cerebral cortex without causing drowsiness due to unchanged θ-waves [5,8,52].”
From l-Theanine as a Functional Food Additive: Its Role in Disease Prevention and Health Promotion (2016) · cites this paper as [52]
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Unno, K., Taguchi, K., Matsuda, T., & Nakamura, Y. (2024) · Molecules · doi:10.3390/molecules29194553 · Cited by 5 · see citing works
Theanine as a promising agent for health-promotion: a review
Wang, Q., Zheng, Y., Ho, C., Huang, J., Guan, X., Lai, C., Gao, H., & Lin, B. (2021) · Journal of Food Bioactives · doi:10.31665/jfb.2020.13257 · Cited by 5 · see citing works
- Authors
- KOBAYASHI, K., NAGATO, Y., AOI, N., JUNEJA, L. R., KIM, M., YAMAMOTO, T., & SUGIMOTO, S.
- Affiliations
- Taiyo Kagaku Co., Ltd. (Japan) (JP)
- Aichi Shukutoku University (JP)
- Venue
- Journal of the agricultural chemical society of Japan
- Published
- 1998
- Volume
- 72
- Issue
- 2
- Pages
- 153-157
- ISSN
- 0002-1407 (ISSN-L)
- 1883-6844
- OpenAlex
- W2055709098
- Cited by
- 123
- References
- 0
- Citations by year
- 2025: 4 · 2024: 6 · 2023: 3 · 2022: 4 · 2021: 8 · 2020: 5 · 2019: 4 · 2018: 2 · 2017: 4 · 2016: 4 · 2015: 8 · 2014: 5 · 2013: 9
- FWCI
- 3.80
- Type
- journal article
- Language
- ja
- Open access
- diamond
- doi.org
- Locations
- Nippon Nōgeikagaku Kaishi (publishedVersion)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plant Extracts Effects
- Health Sciences › Medicine › Pathology and Forensic Medicine › Tea Polyphenols and Effects
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- theanine, alpha oscillations, relaxation, anxiety, caffeine, green tea, serotonergic activity, catecholamines, food additives, functional foods
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