The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Developmental Neurotoxicants in E-Waste: An Emerging Health Concern
Open accessAbstract
OBJECTIVE: Electronic waste (e-waste) has been an emerging environmental health issue in both developed and developing countries, but its current management practice may result in unintended developmental neurotoxicity in vulnerable populations. To provide updated information about the scope of the issue, presence of known and suspected neurotoxicants, toxicologic mechanisms, and current data gaps, we conducted this literature review. DATA SOURCES: We reviewed original articles and review papers in PubMed and Web of Science regarding e-waste toxicants and their potential developmental neurotoxicity. We also searched published reports of intergovernmental and governmental agencies and nongovernmental organizations on e-waste production and management practice. DATA EXTRACTION: We focused on the potential exposure to e-waste toxicants in vulnerable populations-that is, pregnant women and developing children-and neurodevelopmental outcomes. In addition, we summarize experimental evidence of developmental neurotoxicity and mechanisms. DATA SYNTHESIS: In developing countries where most informal and primitive e-waste recycling occurs, environmental exposure to lead, cadmium, chromium, polybrominated diphenyl ethers, polychlorinated biphenyls, and polycyclic aromatic hydrocarbons is prevalent at high concentrations in pregnant women and young children. Developmental neurotoxicity is a serious concern in these regions, but human studies of adverse effects and potential mechanisms are scarce. The unprecedented mixture of exposure to heavy metals and persistent organic pollutants warrants further studies and necessitates effective pollution control measures. CONCLUSIONS: Pregnant women and young children living close to informal e-waste recycling sites are at risk of possible perturbations of fetus and child neurodevelopment.
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Current status of cadmium as an environmental health problem
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Self-citationIntellectual Impairment in Children with Blood Lead Concentrations below 10 μg per Deciliter
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Self-citationDecreased Brain Volume in Adults with Childhood Lead Exposure
Cecil, K. M., Brubaker, C. J., Adler, C. M., Dietrich, K. N., Altaye, M., Egelhoff, J. C., Wessel, S., Elangovan, I., Hornung, R., Jarvis, K., et al. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050112 · Cited by 458
Self-citationInfluence of Prenatal Lead Exposure on Genomic Methylation of Cord Blood DNA
Pilsner, J. R., Hu, H., Ettinger, A., Sánchez, B. N., Wright, R. O., Cantonwine, D., Lazarus, A., Lamadrid-Figueroa, H., Mercado-García, A., Téllez-Rojo, M. M., et al. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800497 · Cited by 275
Unfair Trade e-Waste in Africa
Schmidt, C. W. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.114-a232 · Cited by 243
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Mechanisms of lead and manganese neurotoxicity
Neal, A. P., & Guilarte, T. R. (2013) · Toxicology Research · doi:10.1039/c2tx20064c · Cited by 211
Garg, S., Kumar, P., Mishra, V., Guijt, R., Singh, P., Dumée, L. F., & Sharma, R. S. (2020) · Journal of Water Process Engineering · doi:10.1016/j.jwpe.2020.101683 · Cited by 205
Krčmar, D., Tenodi, S., Grba, N., Kerkez, D., Watson, M., Rončević, S., & Dalmacija, B. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2017.09.283 · Cited by 124
Yuan, J., Liu, Y., Wang, J., Zhao, Y., Li, K., Jing, Y., Zhang, X., Liu, Q., Geng, X., Li, G., et al. (2018) · The Journals of Gerontology: Series A · doi:10.1093/gerona/gly002 · Cited by 53
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Metadata
- Authors
- Chen, A., Dietrich, K. N., Huo, X., & Ho, S.-M.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-04
- Volume
- 119
- Issue
- 4
- Pages
- 431-438
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W1974288475
- Cited by
- 358
- References
- 8
- FWCI
- 23.07
- Type
- journal article
- Language
- en
- Open access
- gold
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