The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Ambient Air Pollution and Atherosclerosis in Los Angeles
Open accessAbstract
Associations have been found between long-term exposure to ambient air pollution and cardiovascular morbidity and mortality. The contribution of air pollution to atherosclerosis that underlies many cardiovascular diseases has not been investigated. Animal data suggest that ambient particulate matter (PM) may contribute to atherogenesis. We used data on 798 participants from two clinical trials to investigate the association between atherosclerosis and long-term exposure to ambient PM up to 2.5 microm in aerodynamic diameter (PM2.5). Baseline data included assessment of the carotid intima-media thickness (CIMT), a measure of subclinical atherosclerosis. We geocoded subjects' residential areas to assign annual mean concentrations of ambient PM2.5. Exposure values were assigned from a PM2.5 surface derived from a geostatistical model. Individually assigned annual mean PM2.5 concentrations ranged from 5.2 to 26.9 microg/m3 (mean, 20.3). For a cross-sectional exposure contrast of 10 microg/m3 PM2.5, CIMT increased by 5.9% (95% confidence interval, 1-11%). Adjustment for age reduced the coefficients, but further adjustment for covariates indicated robust estimates in the range of 3.9-4.3% (p-values, 0.05-0.1). Among older subjects (greater than or equal to 60 years of age), women, never smokers, and those reporting lipid-lowering treatment at baseline, the associations of PM2.5 and CIMT were larger with the strongest associations in women 60 years of age (15.7%, 5.7-26.6%). These results represent the first epidemiologic evidence of an association between atherosclerosis and ambient air pollution. Given the leading role of cardiovascular disease as a cause of death and the large populations exposed to ambient PM2.5, these findings may be important and need further confirmation.
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Citations
Cites
Atherosclerosis--an inflammatory disease
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Cited by
Brook, R. D., Rajagopalan, S., Pope, C. A., Brook, J. R., Bhatnagar, A., Diez-Roux, A. V., Holguin, F., Hong, Y., Luepker, R. V., Mittleman, M. A., et al. (2010) · Circulation · doi:10.1161/cir.0b013e3181dbece1 · Cited by 6,548
Long-term exposure to air pollution and incidence of cardiovascular events in women
Miller, K. A., Siscovick, D. S., Sheppard, L., Shepherd, K., Sullivan, J. H., Anderson, G. L., & Kaufman, J. D. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa054409 · Cited by 1,854
Formation of Urban Fine Particulate Matter
Zhang, R., Wang, G., Guo, S., Zamora, M. L., Ying, Q., Lin, Y., Wang, W., Hu, M., & Wang, Y. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00067 · Cited by 1,426
The effects of ozone on human health
Nuvolone, D., Petri, D., & Voller, F. (2018) · Environmental Science and Pollution Research · doi:10.1007/s11356-017-9239-3 · Cited by 619
Kan, H., London, S. J., Chen, G., Zhang, Y., Song, G., Zhao, N., Jiang, L., & Chen, B. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10851 · Cited by 582
Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge
Stone, V., Miller, M. R., Clift, M. J. D., Elder, A., Mills, N. L., Møller, P., Schins, R. P. F., Vogel, U., Kreyling, W. G., Alstrup Jensen, K., et al. (2017) · Environmental Health Perspectives · doi:10.1289/ehp424 · Cited by 370
Child exposure to indoor and outdoor air pollutants in schools in Barcelona, Spain
Rivas, I., Viana, M., Moreno, T., Pandolfi, M., Amato, F., Reche, C., Bouso, L., Àlvarez-Pedrerol, M., Alastuey, A., Sunyer, J., et al. (2014) · Environment International · doi:10.1016/j.envint.2014.04.009 · Cited by 345
“…is well-known that exposure to air pollutants leads to an increase in mortality and morbidity rates of the population (e.g. Baccarelli et al., 2008; Künzli et al., 2000, 2004; Pope et al., 2002; ackground reference station of ltrafine particles; LDSA, lungrbon; EBC, equivalent black…”
BackgroundA Method to Estimate the Chronic Health Impact of Air Pollutants in U.S. Residences
Logue, J. M., Price, P. N., Sherman, M. H., & Singer, B. C. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104035 · Cited by 251
Schlesinger, R. B., Kunzli, N., Hidy, G. M., Gotschi, T., & Jerrett, M. (2006) · Inhalation Toxicology · doi:10.1080/08958370500306016 · Cited by 245
Self-citationZhu, M.-T., Wang, B., Wang, Y., Yuan, L., Wang, H.-J., Wang, M., Ouyang, H., Chai, Z.-F., Feng, W.-Y., & Zhao, Y.-L. (2011) · Toxicology Letters · doi:10.1016/j.toxlet.2011.03.021 · Cited by 222
Air pollution and circulating biomarkers of oxidative stress
Delfino, R. J., Staimer, N., & Vaziri, N. D. (2011) · Air Quality, Atmosphere & Health · doi:10.1007/s11869-010-0095-2 · Cited by 181
Ozone and daily mortality in Shanghai, China
Zhang, Y., Huang, W., London, S. J., Song, G., Chen, G., Jiang, L., Zhao, N., Chen, B., & Kan, H. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9014 · Cited by 163
Long-term exposure to air pollution and hospitalization for dementia in the Rome longitudinal study
Cerza, F., Renzi, M., Gariazzo, C., Davoli, M., Michelozzi, P., Forastiere, F., & Cesaroni, G. (2019) · Environmental Health · doi:10.1186/s12940-019-0511-5 · Cited by 97
Kotchenruther, R. A. (2016) · Atmospheric Environment · doi:10.1016/j.atmosenv.2016.07.048 · Cited by 69
Metadata
- Authors
- Künzli, N., Jerrett, M., Mack, W. J., Beckerman, B., LaBree, L., Gilliland, F., Thomas, D., Peters, J., & Hodis, H. N.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-02
- Volume
- 113
- Issue
- 2
- Pages
- 201-206
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W1995243424
- Cited by
- 809
- References
- 3
- FWCI
- 24.61
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
