Effects of ambient ozone exposure on mail carriers’ peak expiratory flow rates
Open accessAbstract
The extent to which occupational exposure to ozone in ambient air can affect lung function remains unclear. We conducted a panel study in 43 mail carriers by measuring their peak expiratory flow rates (PEFRs) twice daily for 6 weeks in 2001. The daily exposure of each mail carrier to O3, particulate matter < 10 microm in aerodynamic diameter (PM10), and nitrogen dioxide was estimated by one air monitoring station in the center of the mail carrier's delivery area. Hourly concentrations of air pollutants during their exposure periods were 6-96 ppb for O3, 11-249 microg/m3 for PM10, and 14-92 ppb for NO2. Linear mixed-effects models were used to estimate the association between air pollution exposures and PEFR after adjusting for subject's sex, age, and disease status and for temperature and humidity. We found that night PEFR and the deviation in night PEFR were significantly decreased in association with 8-hr O3 exposures with a lag 0-2 days and by daily maximum O3 exposures with a lag of 0-1 day in our multipollutant models. By contrast, neither PM10 nor NO2 was associated with a PEFR reduction. Daily 8-hr mean concentrations of O3 had greater reduction effects on PEFR than did daily maximum concentrations. For a 10-ppb increase in the 8-hr average O3 concentration, the night PEFR was decreased by 0.54% for a 0-day lag, 0.69% for a 1-day lag, and 0.52% for a 2-day lag. We found that an acute lung function reduction occurs in mail carriers exposed to O3 concentrations below current ambient air quality standards and occupational exposure limits.
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Adverse health responses such as decreases in pulmonary function, alterations in the respiratory tract, and declines in lung function have been observed at O3 levels close to background concentrations.
“Adverse health responses such as decreases in pulmonary function, alterations in the respiratory tract, and declines in lung function have been observed at O3 levels close to background concentrations (Chan and Wu 2005; WHO 2000).”
From The Exposure–Response Curve for Ozone and Risk of Mortality and the Adequacy of Current Ozone Regulations (2006) · cites this paper as Chan and Wu 2005
The Results report decreased peak expiratory flow in mail carriers exposed to ambient ozone, and the Discussion describes lung-function reductions at relatively low concentrations. The paper does not establish that those concentrations were close to background levels, nor does it report observed respiratory-tract alterations in the mail carriers; it discusses possible airway mechanisms instead. Page numbers are not available in our copy. (LLM, conf=0.85)
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The effects of ozone on human health
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- Authors
- Chan, C.-C., & Wu, T.-H.
- Affiliations
- National Taiwan University (TW)
- ORCID
- Chan, Chang-Chuan
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-03-14
- Volume
- 113
- Issue
- 6
- Pages
- 735-738
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- PMC
- PMC1257599
- OpenAlex
- W2073189218
- Cited by
- 45
- References
- 26
- Citations by year
- 2023: 3 · 2022: 4 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 3 · 2017: 3 · 2016: 2 · 2015: 2 · 2014: 3 · 2013: 3 · 2012: 3
- FWCI
- 1.74
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- public-domain
- creativecommons.org/licenses/by/4.0/ (vor, 4673 d)
- Locations
- Environmental Health Perspectives (publishedVersion, public-domain)
- Europe PMC (PubMed Central) (publishedVersion, public-domain)
- PubMed Central (publishedVersion, public-domain)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Keywords
- ambient ozone, peak expiratory flow, lung function, mail carriers, occupational exposure, air pollution exposure, PM10, nitrogen dioxide, acute respiratory effects, air quality standards
- MeSH terms
- Adult, Air Pollutants, Environmental Monitoring, Female, Humans, Male, Nitrogen Dioxide, Ozone, Particle Size, Peak Expiratory Flow Rate, Postal Service, Taiwan, Occupational Exposure, Epidemiological Monitoring
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