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The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Thyroid Hormones in Pregnancy in Relation to Environmental Exposure to Organochlorine Compounds and Mercury

Open access
Takser, Larissa, Mergler, Donna, Baldwin, Mary, de Grosbois, Sylvie, Smargiassi, Audrey, Lafond, Julie·2005·Environmental Health Perspectives

Abstract

Polychlorinated biphenyls (PCBs), chlorinated pesticides, and mercury are global environmental contaminants that can disrupt the endocrine system in animals and humans. However, there is little evidence that they can interfere with endocrine status in pregnant women and neonates at low levels of exposure. The aim of this study was to examine thyroid hormone levels during pregnancy and in cord blood in relation to blood concentrations of organochlorine compounds (OCs) and Hg in healthy women recruited during pregnancy. We found a significant negative correlation between maternal total triiodothyronine levels and three non-coplanar congeners (PCB-138, PCB-153, and PCB-180), three pesticides (p,p -DDE, cis-nanochlor, and hexachlorobenzene), and inorganic Hg independently, without any other changes in thyroid status. No significant relationships were observed between OCs and cord serum thyroid hormones. Cord serum free thyroxin was negatively correlated with inorganic Hg. These results suggest that at even low levels of exposure, persistent environmental contaminants can interfere with thyroid status during pregnancy.

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Metadata

Authors
Takser, L., Mergler, D., Baldwin, M., de Grosbois, S., Smargiassi, A., & Lafond, J.
Venue
Environmental Health Perspectives
Published
2005-08
Volume
113
Issue
8
Pages
1039-1045
ISSN
  • 0091-6765 (ISSN-L)
  • 1552-9924
OpenAlex
W2037863743
Cited by
183
References
5
FWCI
10.60
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Thyroid Hormones in Pregnancy in Relation to Environmental Exposure to Organochlorine Compounds and Mercury. https://app.cochat.ai/papers/10.1289/ehp.7685
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Takser, L., Mergler, D., Baldwin, M., de Grosbois, S., Smargiassi, A., & Lafond, J. (2005). Thyroid Hormones in Pregnancy in Relation to Environmental Exposure to Organochlorine Compounds and Mercury. Environmental Health Perspectives. https://doi.org/10.1289/ehp.7685

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.