State-of-the-science of endocrine disrupting chemicals, 2012
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
BPA is present in polycarbonate plastics, the epoxy lining of canned foods, thermal paper, and other common household products; it is classified as a high volume production compound and continuous low level exposure is virtually ubiquitous and unavoidable.
“Present in polycarbonate plastics, the epoxy lining of canned foods, thermal paper, and other common household products, BPA is classified as a “high volume production” compound and continuous low level (resulting in mean blood levels of 4 ng/ml or lower) exposure is virtually ubiquitous and unavoidable (85).”
From Endocrine Disruption of Vasopressin Systems and Related Behaviors (2017) · cites this paper as [85]
In mouse cerebral cortex, tri-, di-, and monobutyltin altered cholinergic synaptic parameters relevant to neurotransmission.
“Organotin compounds can also directly impair synaptic communication: in mouse cerebral cortex, tri-, di-, and monobutyltin altered cholinergic synaptic parameters relevant to neurotransmission.”
From Environmental endocrine disruptors at the synapse: mechanisms linking chemical exposure to cognitive and behavioral dysfunction (2026) · cites this paper as Bergman et al., 2012
Pesticides are not only general neurotoxicants but can also interfere directly with the molecular and synaptic processes that support neural plasticity.
“Together, these findings indicate that pesticides are not only general neurotoxicants, but can also interfere directly with the molecular and synaptic processes that support neural plasticity (Bergman et al., 2012; Zhou et al., 2023).”
From Environmental endocrine disruptors at the synapse: mechanisms linking chemical exposure to cognitive and behavioral dysfunction (2026) · cites this paper as Bergman et al., 2012
Chlorpyrifos exposure dysregulates synaptic plasticity in rat hippocampal neurons, reducing dendritic spine density and decreasing expression of synaptophysin, PSD-95, GluN1, and GluA1.
“For example, chlorpyrifos exposure dysregulates synaptic plasticity in rat hippocampal neurons, reducing dendritic spine density and decreasing expression of synaptophysin, PSD-95, GluN1, and GluA1.”
From Environmental endocrine disruptors at the synapse: mechanisms linking chemical exposure to cognitive and behavioral dysfunction (2026) · cites this paper as Bergman et al., 2012
Cites
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Guyatt, G. H., Oxman, A. D., Vist, G. E., Kunz, R., Falck-Ytter, Y., Alonso-Coello, P., & Schünemann, H. J. (2008) · BMJ · doi:10.1136/bmj.39489.470347.ad · Cited by 23,305 · see citing works
Hollowell, J. G., Staehling, N. W., Flanders, W. D., Hannon, W. H., Gunter, E. W., Spencer, C. A., & Braverman, L. E. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.2.489 · Cited by 4,279 · see citing works
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
Vandenberg, L. N., Colborn, T., Hayes, T. B., Heindel, J. J., Jacobs, D. R., Lee, D.-H., Shioda, T., Soto, A. M., vom Saal, F. S., Welshons, W. V., et al. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1050 · Cited by 3,209 · see citing works
Self-citationThe Colorado Thyroid Disease Prevalence Study
Canaris, G. J., Manowitz, N. R., Mayor, G., & Ridgway, E. C. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.4.526 · Cited by 2,824 · see citing works
Franks, S. (1995) · New England Journal of Medicine · doi:10.1056/nejm199509283331307 · Cited by 2,463 · see citing works
Sampson, J. A. (1927) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(15)30003-x · Cited by 2,334 · see citing works
Parent, A.-S., Teilmann, G., Juul, A., Skakkebaek, N. E., Toppari, J., & Bourguignon, J.-P. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0019 · Cited by 1,762 · see citing works
In vitro molecular mechanisms of bisphenol A action.
Wetherill, Y. B., Akingbemi, B. T., Kanno, J., McLachlan, J. A., Nadal, A., Sonnenschein, C., Watson, C. S., Zoeller, R. T., & Belcher, S. M. (2007) · Reproductive Toxicology · doi:10.1016/j.reprotox.2007.05.010 · Cited by 920 · see citing works
Self-citationDecrease in eggshell weight in certain birds of prey
RATCLIFFE, D. A. (1967) · Nature · doi:10.1038/215208a0 · Cited by 796 · see citing works
Welsh, M., Saunders, P. T. K., Fisken, M., Scott, H. M., Hutchison, G. R., Smith, L. B., & Sharpe, R. M. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34241 · Cited by 781 · see citing works
Age at menarche and racial comparisons in US girls
Chumlea, W. C., Schubert, C. M., Roche, A. F., Kulin, H. E., Lee, P. A., Himes, J. H., & Sun, S. S. (2003) · PEDIATRICS · doi:10.1542/peds.111.1.110 · Cited by 685 · see citing works
Zoeller, R. T., & Rovet, J. (2004) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2004.01243.x · Cited by 605 · see citing works
Self-citationRier, S. (1993) · Fundamental and Applied Toxicology · doi:10.1006/faat.1993.1119 · Cited by 502 · see citing works
Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing
Crain, D. A., Janssen, S. J., Edwards, T. M., Heindel, J., Ho, S.-M., Hunt, P., Iguchi, T., Juul, A., McLachlan, J. A., Schwartz, J., et al. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.08.067 · Cited by 465 · see citing works
Self-citationEpigenetic Transgenerational Actions of Endocrine Disruptors
Anway, M. D., & Skinner, M. K. (2006) · Endocrinology · doi:10.1210/en.2005-1058 · Cited by 455 · see citing works
Wu, T., Mendola, P., & Buck, G. M. (2002) · Pediatrics · doi:10.1542/peds.110.4.752 · Cited by 394 · see citing works
Maternal levels of perfluorinated chemicals and subfecundity
Fei, C., McLaughlin, J. K., Lipworth, L., & Olsen, J. (2009) · Human Reproduction · doi:10.1093/humrep/den490 · Cited by 385 · see citing works
Åsvold, B. O., Vatten, L. J., Nilsen, T. I. L., & Bjøro, T. (2007) · European Journal of Endocrinology · doi:10.1530/eje.1.02333 · Cited by 350 · see citing works
Pubertal assessment method and baseline characteristics in a mixed longitudinal study of girls
Biro, F. M., Galvez, M. P., Greenspan, L. C., Succop, P. A., Vangeepuram, N., Pinney, S. M., Teitelbaum, S., Windham, G. C., Kushi, L. H., & Wolff, M. S. (2010) · Pediatrics · doi:10.1542/peds.2009-3079 · Cited by 348 · see citing works
Priorities for Endometriosis Research: Recommendations From an International Consensus Workshop
Rogers, P. A. W., D’Hooghe, T. M., Fazleabas, A., Gargett, C. E., Giudice, L. C., Montgomery, G. W., Rombauts, L., Salamonsen, L. A., & Zondervan, K. T. (2009) · Reproductive Sciences · doi:10.1177/1933719108330568 · Cited by 346 · see citing works
Slama, R. (2002) · Human Reproduction · doi:10.1093/humrep/17.2.503 · Cited by 308 · see citing works
Subclinical hyperthyroidism: clinical features and treatment options
Biondi, B., Palmieri, E. A., Klain, M., Schlumberger, M., Filetti, S., & Lombardi, G. (2005) · European Journal of Endocrinology · doi:10.1530/eje.1.01809 · Cited by 217 · see citing works
Åsvold, B. O., Bjøro, T., Nilsen, T. I. L., & Vatten, L. J. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2208 · Cited by 215 · see citing works
Abbott, D. H., Tarantal, A. F., & Dumesic, D. A. (2009) · American Journal of Primatology · doi:10.1002/ajp.20679 · Cited by 177 · see citing works
Wan, W., Farboud, B., & Privalsky, M. L. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0014 · Cited by 61 · see citing works
Colbert, N. K. W., Pelletier, N. C., Cote, J. M., Concannon, J. B., Jurdak, N. A., Minott, S. B., & Markowski, V. P. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7509 · Cited by 60 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
EDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals
Gore, A. C., Chappell, V. A., Fenton, S. E., Flaws, J. A., Nadal, A., Prins, G. S., Toppari, J., & Zoeller, R. T. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1010 · Cited by 2,407 · see citing works
Self-citationEarly Developmental Conditioning of Later Health and Disease: Physiology or Pathophysiology?
Hanson, M. A., & Gluckman, P. D. (2014) · Physiological Reviews · doi:10.1152/physrev.00029.2013 · Cited by 1,188 · see citing works
Metabolism disrupting chemicals and metabolic disorders
Heindel, J. J., Blumberg, B., Cave, M., Machtinger, R., Mantovani, A., Mendez, M. A., Nadal, A., Palanza, P., Panzica, G., Sargis, R., et al. (2017) · Reproductive Toxicology · doi:10.1016/j.reprotox.2016.10.001 · Cited by 1,101 · see citing works
Self-citationCERAPP: Collaborative Estrogen Receptor Activity Prediction Project
Mansouri, K., Abdelaziz, A., Rybacka, A., Roncaglioni, A., Tropsha, A., Varnek, A., Zakharov, A., Worth, A., Richard, A. M., Grulke, C. M., et al. (2016) · Environmental Health Perspectives · doi:10.1289/ehp.1510267 · Cited by 375 · see citing works
Chen, Q., Allgeier, A., Yin, D., & Hollert, H. (2019) · Environment International · doi:10.1016/j.envint.2019.104938 · Cited by 304 · see citing works
Schaider, L. A., Rudel, R. A., Ackerman, J. M., Dunagan, S. C., & Brody, J. G. (2014) · Science of The Total Environment · doi:10.1016/j.scitotenv.2013.08.067 · Cited by 304 · see citing works
Minireview: Endocrine disruptors: Past lessons and future directions
Schug, T. T., Johnson, A. F., Birnbaum, L. S., Colborn, T., Guillette, L. J., Crews, D. P., Collins, T., Soto, A. M., vom Saal, F. S., McLachlan, J. A., et al. (2016) · Molecular Endocrinology · doi:10.1210/me.2016-1096 · Cited by 282 · see citing works
Self-citationAn exposome perspective: Early-life events and immune development in a changing world
Renz, H., Holt, P. G., Inouye, M., Logan, A. C., Prescott, S. L., & Sly, P. D. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.05.015 · Cited by 226 · see citing works
Exploring the planetary boundary for chemical pollution
Diamond, M. L., de Wit, C. A., Molander, S., Scheringer, M., Backhaus, T., Lohmann, R., Arvidsson, R., Bergman, Å., Hauschild, M., Holoubek, I., et al. (2015) · Environment International · doi:10.1016/j.envint.2015.02.001 · Cited by 198 · see citing works
Self-citationSWIFT-Review: a text-mining workbench for systematic review
Howard, B. E., Phillips, J., Miller, K., Tandon, A., Mav, D., Shah, M. R., Holmgren, S., Pelch, K. E., Walker, V., Rooney, A. A., et al. (2016) · Systematic Reviews · doi:10.1186/s13643-016-0263-z · Cited by 196 · see citing works
Schaider, L. A., Ackerman, J. M., & Rudel, R. A. (2016) · Science of The Total Environment · doi:10.1016/j.scitotenv.2015.12.081 · Cited by 182 · see citing works
Transgenerational effects of prenatal bisphenol A on social recognition
Wolstenholme, J. T., Goldsby, J. A., & Rissman, E. F. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.09.007 · Cited by 157 · see citing works
Praegnatio Perturbatio—Impact of Endocrine-Disrupting Chemicals
Padmanabhan, V., Song, W., & Puttabyatappa, M. (2021) · Endocrine Reviews · doi:10.1210/endrev/bnaa035 · Cited by 103 · see citing works
Lee, J. E., & Choi, K. (2017) · Annals of Pediatric Endocrinology & Metabolism · doi:10.6065/apem.2017.22.1.6 · Cited by 92 · see citing works
Seralini, G.-E., & Jungers, G. (2021) · Toxicology Reports · doi:10.1016/j.toxrep.2021.07.014 · Cited by 57 · see citing works
Endocrine Disruption of Vasopressin Systems and Related Behaviors
Patisaul, H. B. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00134 · Cited by 54 · see citing works
Le Moal, J., Sharpe, R. M., Jϕrgensen, N., Levine, H., Jurewicz, J., Mendiola, J., Swan, S. H., Virtanen, H., Christin-Maître, S., Cordier, S., et al. (2016) · The European Journal of Public Health · doi:10.1093/eurpub/ckv153 · Cited by 48 · see citing works
An automated high-throughput SPE micro-elution method for perfluoroalkyl substances in human serum
Huber, S., & Brox, J. (2015) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-015-8601-x · Cited by 46 · see citing works
Endocrine-Disrupting Chemicals in Human Fetal Growth
Street, M. E., & Bernasconi, S. (2020) · Prime Archives in Molecular Biology · doi:10.37247/pamb.1.2020.42 · Cited by 35 · see citing works
Cooper, G. S., Lunn, R. M., Ågerstrand, M., Glenn, B. S., Kraft, A. D., Luke, A. M., & Ratcliffe, J. M. (2016) · Environment International · doi:10.1016/j.envint.2016.03.017 · Cited by 33 · see citing works
Pregnancy-related maternal physiological adaptations and fetal chemical exposure
Vinnars, M.-T., Bixo, M., & Damdimopoulou, P. (2023) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2023.112064 · Cited by 32 · see citing works
Jocsak, G., Kiss, D. S., Alymbaeva, D., Diebald, A., Zsarnovszky, A., Heinzlmann, A., & Bartha, T. (2026) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2026.1821381 · Cited by 1 · see citing works
“Together, these findings indicate that pesticides are not only general neurotoxicants, but can also interfere directly with the molecular and synaptic processes that support neural plasticity (Bergman et al., 2012; Zhou et al., 2023).”
- Authors
- Bergman, Å., Heindel, J., Jobling, S., Kidd, K., & Zoeller, R. T.
- Affiliations
- Stockholm University (SE)
- National Institute of Environmental Health Sciences (US)
- Brunel University of London (GB)
- University of New Brunswick (CA)
- Venue
- Toxicology Letters
- Publisher
- Elsevier BV
- Published
- 2012-06
- Volume
- 211
- Pages
- S3
- ISSN
- 0378-4274 (ISSN-L)
- OpenAlex
- W2092206838
- Cited by
- 1,388
- References
- 26
- Citations by year
- 2026: 27 · 2025: 50 · 2024: 86 · 2023: 88 · 2022: 103 · 2021: 155 · 2020: 142 · 2019: 111 · 2018: 123 · 2017: 127 · 2016: 128 · 2015: 107 · 2014: 97 · 2013: 42
- FWCI
- 51.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Toxicology Letters (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Keywords
- endocrine disruptors, endocrine disruption, ecotoxicology, reproductive toxicity, developmental toxicity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
