The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Synergistic Effects of Traffic-Related Air Pollution and Exposure to Violence on Urban Asthma Etiology
Open accessAbstract
BACKGROUND: Disproportionate life stress and consequent physiologic alteration (i.e., immune dysregulation) has been proposed as a major pathway linking socioeconomic position, environmental exposures, and health disparities. Asthma, for example, disproportionately affects lower-income urban communities, where air pollution and social stressors may be elevated. OBJECTIVES: We aimed to examine the role of exposure to violence (ETV), as a chronic stressor, in altering susceptibility to traffic-related air pollution in asthma etiology. METHODS: We developed geographic information systems (GIS)-based models to retrospectively estimate residential exposures to traffic-related pollution for 413 children in a community-based pregnancy cohort, recruited in East Boston, Massachusetts, between 1987 and 1993, using monthly nitrogen dioxide measurements for 13 sites over 18 years. We merged pollution estimates with questionnaire data on lifetime ETV and examined the effects of both on childhood asthma etiology. RESULTS: Correcting for potential confounders, we found an elevated risk of asthma with a 1-SD (4.3 ppb) increase in NO(2) exposure solely among children with above-median ETV [odds ratio (OR) = 1.63; 95% confidence interval (CI), 1.14-2.33)]. Among children always living in the same community, with lesser exposure measurement error, this association was magnified (OR = 2.40; 95% CI, 1.48-3.88). Of multiple exposure periods, year-of-diagnosis NO(2) was most predictive of asthma outcomes. CONCLUSIONS: We found an association between traffic-related air pollution and asthma solely among urban children exposed to violence. Future studies should consider socially patterned susceptibility, common spatial distributions of social and physical environmental factors, and potential synergies among these. Prospective assessment of physical and social exposures may help determine causal pathways and critical exposure periods.
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Miller, G. E., Chen, E., & Parker, K. J. (2011) · Psychological Bulletin · doi:10.1037/a0024768 · Cited by 1,785
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“Indeed, urban living is associated with various adverse health consequences, such as high-fat diets, sedentary lifestyles, and increased levels of social and psychological stress and environmental pollutants (Clougherty et al., 2007; Lambert et al., 2015; Peer et al., 2003; Sodjinou et al., 2008).”
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Self-citation
Metadata
- Authors
- Clougherty, J. E., Levy, J. I., Kubzansky, L. D., Ryan, P. B., Suglia, S. F., Canner, M. J., & Wright, R. J.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-08
- Volume
- 115
- Issue
- 8
- Pages
- 1140-1146
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W2057310315
- Cited by
- 323
- References
- 51
- FWCI
- 17.05
- Type
- journal article
- Language
- en
- Open access
- gold
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- Clougherty, J. E., Levy, J. I., Kubzansky, L. D., Ryan, P. B., Suglia, S. F., Canner, M. J., & Wright, R. J. (2007). Synergistic Effects of Traffic-Related Air Pollution and Exposure to Violence on Urban Asthma Etiology. Environmental Health Perspectives. https://doi.org/10.1289/ehp.9863
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