The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Effects of Administration of TOS and Bifidobacterium breve 4006 on the Human Fecal Flora
Open accessAbstract
We studied the effects of administration of TOS, a new growth factor derived from lactose for Bifidobacterium, and Bifidobacterium breve 4006 on the fecal flora of normal subjects. All of the Bifidobacterium species tested, eight reference strains and B. breve 4006 were capable of fermenting TOS in vitro, while others, 2 Bacteroides strains and 4 Lactobacillus and Enterobacteriaceae strains, showed an appreciable growth among 55 cultures tested. It was evident that TOS is not intestinally absorbed by the recipient subjects, from hydrogen breath test. In vivo, TOS (3g or 10g/day) was observed to promote the growth of both administered B. breve 4006 and resident Bifidobacterium strains. Simultaneous administration of B. breve 4006 and TOS caused the suppression of gram negative anaerobes and aerobes, Bacteroidaceae and Enterobacteriaceae, and the reduction of fecal ammonia and urinary indican excretion. It is concluded that TOS is a typical bifidus factor.
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Stark, P. L., & Lee, A. (1982) · Journal of Medical Microbiology · doi:10.1099/00222615-15-2-189 · Cited by 616
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Benefaction of probiotics for human health: A review
George Kerry, R., Patra, J. K., Gouda, S., Park, Y., Shin, H.-S., & Das, G. (2018) · Journal of Food and Drug Analysis · doi:10.1016/j.jfda.2018.01.002 · Cited by 898
Probiotic Spectra of Lactic Acid Bacteria (LAB)
Naidu, A. S., Bidlack, W. R., & Clemens, R. A. (1999) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408699991279187 · Cited by 698
Krumbeck, J. A., Rasmussen, H. E., Hutkins, R. W., Clarke, J., Shawron, K., Keshavarzian, A., & Walter, J. (2018) · Microbiome · doi:10.1186/s40168-018-0494-4 · Cited by 342
Synbiotics in Health and Disease
Kolida, S., & Gibson, G. R. (2011) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-022510-133739 · Cited by 309
Metadata
- Authors
- TANAKA, R., TAKAYAMA, H., MOROTOMI, M., KUROSHIMA, T., UEYAMA, S., MATSUMOTO, K., KURODA, A., & MUTAI, M.
- Venue
- Bifidobacteria and Microflora
- Publisher
- BMFH Press
- Published
- 1983
- Volume
- 2
- Issue
- 1
- Pages
- 17-24
- ISSN
- 0286-9306 (ISSN-L)
- 1884-5126
- OpenAlex
- W2051782830
- Cited by
- 246
- References
- 1
- FWCI
- 2.04
- Type
- journal article
- Language
- en
- Open access
- diamond
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- CoChat. (2026). Citation check: Effects of Administration of TOS and Bifidobacterium breve 4006 on the Human Fecal Flora. https://app.cochat.ai/papers/10.12938/bifidus1982.2.1_17
- The paper
- TANAKA, R., TAKAYAMA, H., MOROTOMI, M., KUROSHIMA, T., UEYAMA, S., MATSUMOTO, K., KURODA, A., & MUTAI, M. (1983). Effects of Administration of TOS and Bifidobacterium breve 4006 on the Human Fecal Flora. Bifidobacteria and Microflora. https://doi.org/10.12938/bifidus1982.2.1_17
Data sources
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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