Benefaction of probiotics for human health: A review
Open accessAbstract
Humans are a unique reservoir of heterogeneous and vivacious group of microbes, which together forms the human-microbiome superorganism. Human gut serves as a home to over 100-1000 microbial species, which primarily modulate the host internal environment and thereby, play a major role in host health. This spectacular symbiotic relationship has attracted extensive research in this field. More specifically, these organisms play key roles in defense function, eupepsia along with catabolism and anabolism, and impact brain-gut responses. The emergence of microbiota with resistance and tolerance to existing conventional drugs and antibiotics has decreased the drug efficacies. Furthermore, the modern biotechnology mediated nano-encapsulated multiplex supplements appear to be high cost and inconvenient. Henceforth, a simple, low-cost, receptive and intrinsic approach to achieve health benefits is vital in the present era. Supplementation with probiotics, prebiotics, and synbiotics has shown promising results against various enteric pathogens due to their unique ability to compete with pathogenic microbiota for adhesion sites, to alienate pathogens or to stimulate, modulate and regulate the host's immune response by initiating the activation of specific genes in and outside the host intestinal tract. Probiotics have also been shown to regulate fat storage and stimulate intestinal angiogenesis. Hence, this study aims to underline the possible beneficial impact of probiotics for human health and medical sectors and for better lifestyle.
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Probiotics can have an anti-obesity effect.
“probiotics can also have an anti-cancer, anti-obesity, and anti-diabetes effect [3].”
From Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity (2021) · cites this paper as [3]
Probiotics play an essential role in maintaining human health.
“a large number of studies have proven that probiotics play an essential role in maintaining human health.”
From Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity (2021) · cites this paper as [3]
Probiotics can have an anti-cancer effect.
“probiotics can also have an anti-cancer, anti-obesity, and anti-diabetes effect [3].”
From Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity (2021) · cites this paper as [3]
The composition and products of intestinal microorganisms have a great influence on the immune response.
“the composition and products of intestinal microorganisms have a great influence on the immune response [3,4].”
From Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity (2021) · cites this paper as [3]
Probiotics can have an anti-diabetes effect.
“probiotics can also have an anti-cancer, anti-obesity, and anti-diabetes effect [3].”
From Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity (2021) · cites this paper as [3]
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- Authors
- George Kerry, R., Patra, J. K., Gouda, S., Park, Y., Shin, H.-S., & Das, G.
- Affiliations
- Dongguk University (KR)
- Amity University (IN)
- Corresponding author
- Das, Gitishree
- Venue
- Journal of Food and Drug Analysis
- Published
- 2018-07
- Volume
- 26
- Issue
- 3
- Pages
- 927-939
- ISSN
- 1021-9498 (ISSN-L)
- PMC
- PMC9303019
- OpenAlex
- W2793166738
- Cited by
- 898
- References
- 130
- Citations by year
- 2026: 51 · 2025: 94 · 2024: 112 · 2023: 126 · 2022: 150 · 2021: 133 · 2020: 133 · 2019: 72 · 2018: 26 · 2015: 1
- FWCI
- 9.23
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Food and Drug Analysis (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (IPET)
- Ministry of Agriculture, Food and Rural Affairs (MAFRA) (710003-07-7-SB120, 116075-3)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Keywords
- probiotics, prebiotics, synbiotics, gut microbiota, host immune response, antibiotic resistance, enteric pathogens, pathogen adhesion, gut-brain axis, health benefits
- MeSH terms
- Gastrointestinal Microbiome, Animals, Diabetes Mellitus, Health, Humans, Neoplasms, Obesity, Probiotics
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