The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Human acellular dermal wound matrix for treatment of DFU: literature review and analysis
Abstract
Diabetic foot ulcers (DFUs) affect a significant number of people and the treatment is challenging and costly. Since only a small portion of patients respond to standard care, the majority require more advanced wound healing interventions. Human acellular dermal matrices—regenerative tissue matrices derived from human tissue and processed from screened donated skin—can aid wound closure by restoring the missing physiological factors to the microenvironment. A literature review of the clinical literature was performed to estimate the comparative effectiveness of one specific human acellular dermal wound matrix (HADWM; Graftjacket regenerative tissue matrix) versus standard care in healing DFUs. Outcomes from three prospective, controlled clinical trials, which included 154 patients with DFUs, were pooled. A comparative analysis revealed a statistically significant reduction in mean wound healing time, 1.7 weeks, as well as a nearly four-fold improvement in the chance of healing ulcers treated with HADWM versus moist wound-care. These pooled results suggest that HADWM may improve healing outcomes for these difficult-to-heal lower extremity wounds. Declaration of interest: Alexander Reyzelman is a consultant for KCI, an Acelity company.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Many studies have demonstrated that these dermal matrices are effective when applied as adjuvant treatment to enhance DFUs healing [17–19].”
From Effectiveness and safety of dermal matrix used for diabetic foot ulcer: a systematic review and meta-analysis of randomized controlled trials (2024) · cites this paper as [17]
In the citing paper
“Reyzelman A.M. et al. [34] conducted a literature review and analysis of one specific human acellular dermal wound matrix(-Graftjacket) in 2015, three studies containing 154 DFUs were included.”
From Efficacy and safety of acellular dermal matrix in diabetic foot ulcer treatment: A systematic review and meta-analysis (2017) · cites this paper as [34]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Xenogeneic extracellular matrix as a scaffold for tissue reconstruction
Badylak, S. F. (2004) · Transplant Immunology · doi:10.1016/j.trim.2003.12.016 · Cited by 747
Organ engineering based on decellularized matrix scaffolds
Song, J. J., & Ott, H. C. (2011) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2011.03.005 · Cited by 501
Research works printed but not linked: 41
- 10.2337/diacare.26.6.1879 · DOI
- 10.1172/JCI32169 · DOI
- 10.1097/00129334-200506000-00012 · DOI
- 10.1053/apmr.2001.23780 · DOI
- 10.1016/S0140-6736(05)67695-7 · DOI · Paper page
- 10.2337/dc07-2196 · DOI
- 10.2337/diacare.26.6.1701 · DOI · Paper page
- 10.2337/diacare.24.2.290 · DOI · Paper page
- 10.1111/j.1742-481X.2009.00585.x · DOI · Paper page
- 10.7547/1000385 · DOI
- 10.1016/0305-4179(95)93866-I · DOI · Paper page
- 10.1016/j.suc.2010.08.004 · DOI
- 10.1097/00006123-199908000-00025 · DOI
- 10.1016/j.cpm.2009.08.001 · DOI
- Harding K., 2010, Wounds International, 1
- 10.1111/j.1742-481X.2006.00209.x · DOI
- Brigido S.A., 2004, Orthopedics, 27, s145, 10.3928/0147-7447-20040102-14 · DOI · Paper page
- 10.1111/j.1742-4801.2005.00099.x · DOI · Paper page
- Higgins J.P., 2011, Cochrane Handbook for Systematic Reviews of Interventions Part 2: General Methods for Cochrane Reviews
- 10.1002/sim.1186 · DOI · Paper page
- Stacey D.H., 2013, Eplasty, 13, e61
- 10.1097/SCS.0b013e3181bf85a6 · DOI
- 10.1097/SAP.0b013e31824189ed · DOI
- 10.1053/j.jfas.2010.12.015 · DOI
- 10.2174/157339912800563963 · DOI
- 10.3113/FAI.2008.0329 · DOI
- Chen B., 2008, Zhonghua Shao Shang Za Zhi, 24, 355
- Chen X.L., 2008, Ann Burns Fire Disasters, 21, 102
- 10.1097/01.sap.0000215288.83924.6c · DOI
- 10.1053/j.jfas.2007.05.007 · DOI
- 10.1053/j.jfas.2007.08.015 · DOI
- 10.7547/0980104 · DOI
- 10.3113/FAI.2010.0136 · DOI
- 10.1177/1938640009333474 · DOI
- Kimmel H., 2010, J Am Coll Cert Wound Spec, 2, 55
- 10.1177/107110078100200202 · DOI
- Lavery L.A., 1997, Ostomy Wound Manage, 43, 44
- 10.1016/j.jvs.2005.01.042 · DOI · Paper page
- 10.1111/j.1742-481X.2007.00300.x · DOI
- 10.1016/j.jvs.2010.06.003 · DOI
- 10.1097/01.ASW.0000323532.98003.26 · DOI · Paper page
Cited by
Guo, X., Mu, D., & Gao, F. (2017) · International Journal of Surgery · doi:10.1016/j.ijsu.2017.02.008 · Cited by 80
Jiang, F.-H., Liu, X.-M., Yu, H.-R., Qian, Y., & Chen, H.-L. (2022) · The International Journal of Lower Extremity Wounds · doi:10.1177/1534734620929892 · Cited by 65
Sui, L., Xie, Q., Jiang, H.-T., & Li, X.-D. (2024) · BMC Endocrine Disorders · doi:10.1186/s12902-024-01550-3 · Cited by 14
Metadata
- Authors
- Reyzelman, A. M.
- Affiliations
- California School of Podiatric Medicine, San Francisco, CA, USA
- Venue
- Journal of Wound Care
- Publisher
- Mark Allen Group
- Published
- 2015-03-02
- Volume
- 24
- Issue
- 3
- Pages
- 128-134
- ISSN
- 0969-0700
- 2052-2916
- Cited by
- 26
- References
- 2
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Human acellular dermal wound matrix for treatment of DFU: literature review and analysis. https://app.cochat.ai/papers/10.12968/jowc.2015.24.3.128
- The paper
- Reyzelman, A. M. (2015). Human acellular dermal wound matrix for treatment of DFU: literature review and analysis. Journal of Wound Care. https://doi.org/10.12968/jowc.2015.24.3.128
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
