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Cited by 265

The DOI matches its Crossref record; 87 of the 87 references it cites were found in a registry or an index.

Soy Isoflavones: a Safety Review

Munro, Ian C., Harwood, Melody, Hlywka, Jason J., Stephen, Alison M., Doull, John, Flamm, W. Gary, Adlercreutz, Herman·2003·Nutrition Reviews
DOI 10.1301/nr.2003.janr.1-33
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Abstract

Soy isoflavones have been a component of the diet of certain populations for centuries. The consumption of soy generally has been considered beneficial, with a potentially protective effect against a number of chronic diseases; because of their estrogenic activity, however, negative effects of isoflavones have been postulated. This review examines the literature associated with the safety of soy isoflavones, including dietary soy isoflavone exposure data of populations with high soy intakes, human studies in which soy protein or isoflavones were provided, and toxicologic studies investigating the potential genotoxicity, carcinogenicity, and reproductive and developmental toxicity of soy isoflavones. Whereas results in some studies are limited or conflicting, when viewed in its entirety, the current literature supports the safety of isoflavones as typically consumed in diets based on soy or containing soy products.

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Metadata

Authors
Munro, I. C., Harwood, M., Hlywka, J. J., Stephen, A. M., Doull, J., Flamm, W. G., & Adlercreutz, H.
Venue
Nutrition Reviews
Publisher
Oxford University Press (OUP)
Published
2003-01-01
Volume
61
Issue
1
Pages
1-33
ISSN
  • 0029-6643 (ISSN-L)
  • 1753-4887
DOI
10.1301/nr.2003.janr.1-33
OpenAlex
W2157495240
Cited by
265
References
87
FWCI
14.55
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Soy Isoflavones: a Safety Review. https://app.cochat.ai/papers/10.1301/nr.2003.janr.1-33
The paper
Munro, I. C., Harwood, M., Hlywka, J. J., Stephen, A. M., Doull, J., Flamm, W. G., & Adlercreutz, H. (2003). Soy Isoflavones: a Safety Review. Nutrition Reviews. https://doi.org/10.1301/nr.2003.janr.1-33

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.