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THE VASCULAR CONTRIBUTION TO OSTEOGENESIS: III. Changes in the Growth Cartilage Caused by Experimentally Induced Ischaemia
Open accessAbstract
In this work the role of the blood vessels surrounding the epiphysial growth plate has been studied. The nutritional dependence of the proliferative cells on the epiphysial vessels has been established whereas the metaphysial vessels were seen to take part in calcification and ossification at the metaphysis. As it does not seem likely that the blood circulating in the two systems of vessels had a different constitution, particularly in hormones and vitamins, it seems permissible to assume that it is the characteristics, particularly in shape and number, of such vessels that make growth the orderly process it is, with the repeated birth of a cell at the top of a column and burial at the bottom end. But, despite this undeniable role of the vessels, growth depends on the ability of the cartilage cell to form a matrix which, in due course, will be avid for apatite crystals.
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Cited by
Mechanism of the Stimulatory Effect of Growth Hormone on Longitudinal Bone Growth*
ISAKSSON, O. G. P., LINDAHL, A., NILSSON, A., & ISGAARD, J. (1987) · Endocrine Reviews · doi:10.1210/edrv-8-4-426 · Cited by 580
Skeletal defects in VEGF120/120 mice reveal multiple roles for VEGF in skeletogenesis
Zelzer, E., McLean, W., Ng, Y.-S., Fukai, N., Reginato, A. M., Lovejoy, S., D’Amore, P. A., & Olsen, B. R. (2002) · Development · doi:10.1242/dev.129.8.1893 · Cited by 445
Thompson, E. M., Matsiko, A., Farrell, E., Kelly, D. J., & O'Brien, F. J. (2015) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.1918 · Cited by 147
Metadata
- Authors
- Trueta, J., & Amato, V. P.
- Venue
- The Journal of Bone and Joint Surgery. British volume
- Published
- 1960-08
- Volume
- 42-B
- Issue
- 3
- Pages
- 571-587
- ISSN
- 0301-620X (ISSN-L)
- 2044-5377
- OpenAlex
- W2396134644
- Cited by
- 333
- References
- 0
- FWCI
- 4.57
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: THE VASCULAR CONTRIBUTION TO OSTEOGENESIS: III. Changes in the Growth Cartilage Caused by Experimentally Induced Ischaemia. https://app.cochat.ai/papers/10.1302/0301-620x.42b3.571
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- Trueta, J., & Amato, V. P. (1960). THE VASCULAR CONTRIBUTION TO OSTEOGENESIS: III. Changes in the Growth Cartilage Caused by Experimentally Induced Ischaemia. The Journal of Bone and Joint Surgery. British volume. https://doi.org/10.1302/0301-620x.42b3.571
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.