Cited by 387Orthopaedic implants and arthroplastyOrthopedic Infections and TreatmentsTitanium Alloys Microstructure and Properties

The DOI matches its Crossref record.

Composition and morphology of wear debris in failed uncemented total hip replacement

Shanbhag, AS, Jacobs, JJ, Glant, TT, Gilbert, JL, Black, J, Galante, JO·1994·The Journal of Bone and Joint Surgery. British volume

DOI 10.1302/0301-620x.76b1.8300684

Open this paper in CoChat — free account

Abstract

Interfacial membranes collected at revision from 11 failed uncemented Ti-alloy total hip replacements were examined. Particles in the membranes were characterised by electron microscopy, microchemical spectroscopy and particle size analysis. Most were polyethylene and had a mean size of 0.53 micron +/- 0.3. They were similar to the particles seen in the base resin used in the manufacture of the acetabular implants. Relatively few titanium particles were seen. Fragments of bone, stainless steel and silicate were found in small amounts. Most of the polyethylene particles were too small to be seen by light microscopy. Electron microscopy and spectroscopic techniques are required to provide an accurate description of this debris.

Integrity signals

Registry

Crossref · 10.1302/0301-620x.76b1.8300684

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Sorted by citations

Items 101–200 of 325

The lubrication of metal-on-metal total hip joints: A slide down the Stribeck curve
Smith, S., Dowson, D., & Goldsmith, A. (2001) · doi:10.1243/1350650011543718 · Cited by 61
Ultrahigh molecular weight polyethylene particles have direct effects on proliferation, differentiation, and local factor production of MG63 osteoblast‐like cells
Dean, D., Schwartz, Z., Blanchard, C., Liu, Y., Agrawal, C., Lohmann, C., Sylvia, V., & Boyan, B. (1999) · Journal of Orthopaedic Research · doi:10.1002/jor.1100170104 · Cited by 61
Cobalt ions induce chemokine secretion in primary human osteoblasts
Queally, J., Devitt, B., Butler, J. S., Malizia, A., Murray, D., Doran, P., & O'Byrne, J. (2009) · Journal of Orthopaedic Research · doi:10.1002/jor.20837 · Cited by 60
“Other studies also tend to use metal particles as opposed to ions as the stimulating form of wear debris, as the majority of disseminated particles from implants are submicrometer in size.(64) It is not clear however, whether the particles stimulate osteolysis directly via phagocytosis or via ionic products released a…”
Background
The microstructure of ultra-high molecular weight polyethylene used in total joint replacements.
Farrar, D., & Brain, A. A. (1997) · Biomaterials · doi:10.1016/s0142-9612(97)00143-9 · Cited by 60
Wear of ultra high molecular weight polyethylene in total artificial joints
Fisher, J. (1994) · doi:10.1016/0268-0890(94)90048-5 · Cited by 60
Effects of polyethylene and TiAIV wear particles on expression of RANK, RANKL and OPG mRNA
Baumann, B., Rader, C., Seufert, J., Nöth, U., Rolf, O., Eulert, J., & Jakob, F. (2004) · Acta Orthopaedica Scandinavica · doi:10.1080/00016470410001222 · Cited by 59
“…wear debris from periprosthetic tissues have emphasized the most important role of polyethylene particles, and have demonstrated that 70–90% of the particles recovered are submicrometer polyethylene particles (Shanbhag et al. 1994, Campbell et al. 1995, Maloney et al. 1995, Hirakawa et al. 1996).”
Background
Factors contributing to rapid wear and osteolysis in hips with modular acetabular bearings made of hylamer.
Scott, D. L., Campbell, P., McClung, C., & Schmalzried, T. (2000) · Journal of Arthroplasty · doi:10.1016/s0883-5403(00)91103-3 · Cited by 59
How has the biologic reaction to wear particles changed with newer bearing surfaces?
Jacobs, J., Campbell, P., & Konttinen, Y. (2008) · Journal of the American Academy of Orthopaedic Surgeons · doi:10.5435/00124635-200800001-00011 · Cited by 58
Self-citation
Effect of particle size on biological response by human monocyte-derived macrophages
Chikaura, H., Nakashima, Y., Fujiwara, Y., Komohara, Y., Takeya, M., & Nakanishi, Y. (2016) · doi:10.1016/j.bsbt.2016.02.003 · Cited by 57
Effects of Orthopaedic Polymer Particles on Chemotaxis of Macrophages and Mesenchymal Stem Cells
Huang, Z.-N., Ma, T., Ren, P.-G., Smith, R. L., & Goodman, S. B. (2010) · Journal of Biomedical Materials Research. Part A · doi:10.1002/jbm.a.32803 · Cited by 56
Particle analysis for the determination of UHMWPE wear.
Scott, M., Morrison, M., Mishra, S. R., & Jani, S. (2005) · Journal of Biomedical Materials Research. Part B - Applied biomaterials · doi:10.1002/jbm.b.30213 · Cited by 56
CERAMIC-CERAMIC AND METAL-POLYETHYLENE TOTAL HIP REPLACEMENTS: COMPARISON OF PSEUDOMEMBRANES AFTER LOOSENING
Lerouge, S., Huk, O., Yahia, L., Witvoet, J., & Sedel, L. (1997) · doi:10.1302/0301-620x.79b1.6621 · Cited by 56
Ectopic bone formation via rhBMP-2 delivery from porous bioabsorbable polymer scaffolds
Whang, K., Tsai, D. C., Nam, E. K., Aitken, M. E., Sprague, S. M., Patel, P. K., & Healy, K. E. (1998) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(19981215)42:4 · Cited by 211
The balance between endotoxin accumulation and clearance during particle‐induced osteolysis in murine calvaria
Tatro, J. M., Taki, N., Islam, A. S., Goldberg, V. M., Rimnac, C. M., Doerschuk, C. M., Stewart, M. C., & Greenfield, E. M. (2006) · Journal of Orthopaedic Research® · doi:10.1002/jor.20289 · Cited by 51
“Polyethylene particleswere chosen for this purpose because they are the most common type found in patients with aseptic loosening.(29,32)Moreover, we considered it important to examine both oxidized and nonoxidized polyethylene, because their different surface chemistries(33) might cause differences in endotoxin accum…”
Effect of PMMA particles and movement on an implant interface in a canine model.
Jones, L. C., Frondoza, C., & Hungerford, D. (2001) · Journal of Bone and Joint Surgery-british Volume · doi:10.1302/0301-620x.83b3.10734 · Cited by 54
“Large quantities of polyethylene (PE), polymethylmethacrylate (PMMA) and metal alloy particles have been identified in periprosthetic tissues.(11-23) Analysis has indicated that there is a preponderance of submicron particles which can be easily phagocytosed by the cells located within the membrane.”
Background
An in vivo murine model of continuous intramedullary infusion of polyethylene particles.
Ma, T., Huang, Z.-N., Ren, P.-G., McCally, R. E., Lindsey, D. P., Smith, R., & Goodman, S. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.05.031 · Cited by 52
“5um in diameter [9–11].”
Isolation and morphological characterisation of UHMWPE wear debris generated in vitro.
Affatato, S., Fernandes, B., Tucci, A., Esposito, L., & Toni, A. (2001) · Biomaterials · doi:10.1016/s0142-9612(00)00403-8 · Cited by 52
Synthetic nano-fibrillar extracellular matrices with predesigned macroporous architectures
Zhang, R., & Ma, P. X. (2000) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(200011)52:2 · Cited by 265
Chemokine IL‐8 induction by particulate wear debris in osteoblasts is mediated by NF‐κB
Fritz, E. A., Jacobs, J. J., Glant, T., & Roebuck, K. (2005) · Journal of Orthopaedic Research · doi:10.1016/j.orthres.2005.03.013.1100230603 · Cited by 49
Self-citation
Sealing effect of hydroxyapatite coating: A 12-month study in canines
Rahbek, O., Overgaard, S., Jensen, T., Bendix, K., & Søballe, K. (2000) · Acta Orthopaedica Scandinavica · doi:10.1080/000164700317362181 · Cited by 49
“However, the size of the particles ranged from 0.2 to 10 and therefore contained submicron particles, which are primarily found around hip implants in vivo (Shanbhag et al. 1994, McKellop et al. 1995).”
BackgroundInfluential
The role of polyethylene wear in joint replacement failure
McGee, M., Howie, D., Neale, S., Haynes, D. R., & Pearcy, M. (1997) · Proceedings of the Institution of mechanical engineers. Part H, journal of engineering in medicine · doi:10.1243/0954411971534692 · Cited by 48
Nonsurgical Management of Osteolysis
Talmo, C. T., Shanbhag, A. S., & Rubash, H. E. (2006) · Clinical Orthopaedics and Related Research · doi:10.1097/01.blo.0000246531.59876.a8 · Cited by 43
Self-citation
Vitamin E-Diffused Highly Cross-Linked UHMWPE Particles Induce Less Osteolysis Compared to Highly Cross-Linked Virgin UHMWPE Particles In Vivo
Bichara, D. A., Malchau, E., Sillesen, N. H., Çakmak, S., Nielsen, G. P., & Muratoglu, O. K. (2014) · The Journal of Arthroplasty · doi:10.1016/j.arth.2014.03.044 · Cited by 54
Review of wear mechanisms in hip implants: Paper II: ceramics IG004712
Slonaker, M., & Goswami, T. (2004) · doi:10.1016/j.matdes.2003.11.011 · Cited by 45
Nitric Oxide and Prostaglandin E2 Production in Response to Ultra-High Molecular Weight Polyethylene Particles Depends on Osteoblast Maturation State
Lohmann, C., Dean, D., Bonewald, L., Schwartz, Z., & Boyan, B. (2002) · Journal of Bone and Joint Surgery. American volume · doi:10.2106/00004623-200203000-00012 · Cited by 44
Metal-on-metal vs. metal-on-polyethylene total hip arthroplasty tribological evaluation of retrieved components and periprosthetic tissue.
Topolovec, M., Cör, A., & Milošev, I. (2014) · Journal of The Mechanical Behavior of Biomedical Materials · doi:10.1016/j.jmbbm.2014.02.018 · Cited by 43
“Other studies dealing with particles isolated from tissue reported somewhat higher values, 0.53 (SD 0.3) mm (Shanbhag et al., 1994), 0.5 (SD 0.3) mm (Maloney et al., 1995) and from 0.58 to 0.79 mm (Margevicius et al., 1994).”
BackgroundInfluential
A prospective randomized study comparing electrochemically deposited hydroxyapatite and plasma-sprayed hydroxyapatite on titanium stems
Bøe, B., Röhrl, S., Heier, T., Snorrason, F., & Nordsletten, L. (2011) · Acta Orthopaedica · doi:10.3109/17453674.2010.548027 · Cited by 43
“Fewer particles in the joint mean less third-body wear and less periprosthetic osteolysis (Peters et al. 1992, Shanbhag et al. 1994, Campbell et al. 1995, McKellop et al. 1995).”
Background
The effect of counterface roughness on the wear of UHMWPE for rectangular wear paths
Turell, M., Friedlaender, G., Wang, A.-G., Thornhill, T., & Bellare, A. (2005) · doi:10.1016/j.wear.2005.01.050 · Cited by 43
Benign cellular responses in rats to different wear particles in intra-articular and intramedullary environments.
van der Vis, H. M., Marti, R., Tigchelaar, W., Schuller, H. M., & van Noorden, C. V. (1997) · Journal of Bone and Joint Surgery-british Volume · doi:10.1302/0301-620x.79b5.0790837 · Cited by 43
Intercalary replacement of canine femora using a new bioactive bone cement.
Senaha, Y., Nakamura, T., Tamura, J., Kawanabe, K., Iida, H., & Yamamuro, T. (1996) · Journal of Bone and Joint Surgery-british Volume · doi:10.1302/0301-620x.78b1.0780026 · Cited by 43
“In addition, the wear debris from high-density polyethylene (HDP), PMMA cement and metal may be taken up by macrophages in fibrous tissue (Willert, Bertram and Buchorn 1990; Manley and Serekian 1994; Shanbhag et al 1994).”
Background
Activation of NF‐KB signalling and TNFα‐expression in THP‐1 macrophages by TiAlV‐ and polyethylene‐wear particles
Baumann, B., Seufert, J., Jakob, F., Nöth, U., Rolf, O., Eulert, J., & Rader, C. (2005) · doi:10.1016/j.orthres.2005.02.017.1100230602 · Cited by 42
Wear debris and cytokine production in the interface membrane of loosened prostheses.
Stea, S., Visentin, M., Granchi, D., Melchiorri, C., Soldati, S., Sudanese, A., Toni, A., Montanaro, L., & Pizzoferrato, A. (1999) · Journal of Biomaterials Science. Polymer Edition · doi:10.1163/156856299x00162 · Cited by 42
Interactions between mammalian cells and nano- or micro-sized wear particles: physico-chemical views against biological approaches.
Prokopovich, P. (2014) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2014.09.001 · Cited by 41
“Wear debris retrieved from in vivo samples revealed polyethylene particles to be spherical with a diameter of 0.1–1.5 µm [40] , [41] , [35] .”
Influential
The prediction of polyethylene wear rate and debris morphology produced by microscopic asperities on femoral heads
Mcnie, C., Barton, D. C., Ingham, E., Tipper, J., Fisher, J., & Stone, M. H. (2000) · Journal of materials science. Materials in medicine · doi:10.1023/a:1008979608563 · Cited by 41
Chronic antigen-specific immune-system activation may potentially be involved in the loosening of cemented acetabular components
Farber, A., Chin, R., Song, Y., Huie, P., & Goodman, S. B. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(20010605)55:3 · Cited by 29
Influence of design and bearing material on polyethylene wear particle generation in total knee replacement.
Utzschneider, S., Paulus, A., Datz, J.-C., Schroeder, C., Sievers, B., Wegener, B., & Jansson, V. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.03.016 · Cited by 40
Analysis of polyethylene particles isolated from periprosthetic tissue of loosened hip arthroplasty and comparison with radiographic appearance
Koseki, H., Matsumoto, T., Ito, S., Doukawa, H., Enomoto, H., & Shindo, H. (2005) · Journal of Orthopaedic Science · doi:10.1007/s00776-005-0896-6 · Cited by 40
Inhibitory effect of (-)-epigallocatechin gallate on titanium particle-induced TNF-α release and in vivo osteolysis
Jin, S., Park, J.-Y., Hong, J.-M., Kim, T.-H., Shin, H.-I., Park, E., & Kim, S.-Y. (2011) · Experimental and Molecular Medicine · doi:10.3858/emm.2011.43.7.045 · Cited by 39
“In a canine model, bisphosphonates such as alendronate dramatically reduce osteolysis without affecting the inflammatory response (Shanbhag et al., 1994a, 1994b, 1997).”
Background
Anabolic effects of bisphosphonates on peri-implant bone stock
von Knoch, F., Eckhardt, C. M., Alabre, C. I., Schneider, E. H., Rubash, H. E., & Shanbhag, A. S. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.04.024 · Cited by 36
Self-citation
Superior sealing effect of hydroxyapatite in porous-coated implants
Rahbek, O., Kold, S., Bendix, K., Overgaard, S., & Søballe, K. (2005) · Acta Orthopaedica · doi:10.1080/00016470510030850 · Cited by 39
Periprosthetic bone loss: diagnostic and therapeutic approaches
Cavalli, L., & Brandi, M. L. (2013) · F1000Research · doi:10.12688/f1000research.2-266.v2 · Cited by 39
Femoral bone adaptation to stable long-term cemented total hip arthroplasty in dogs.
Bergh, M. S., Muir, P., Markel, M., & Manley, P. (2004) · Veterinary surgery · doi:10.1111/j.1532-950x.2004.04032.x · Cited by 38
The acetabular insert-metal backing interface: an additional source of polyethylene wear debris.
Wasielewski, R., Jacobs, J., Arthurs, B., & Rubash, H. (2005) · Journal of Arthroplasty · doi:10.1016/j.arth.2005.04.033 · Cited by 37
“Polyethylene wear debris and the associated granulomatous response are implicated as the cause of this bone loss and implant failure [3-6,11-30].”
BackgroundSelf-citation
A controlled experimental model of revision implants: Part I. Development
Bechtold, J., Kubic, V., & Søballe, K. (2001) · Acta Orthopaedica Scandinavica · doi:10.1080/000164701317269094 · Cited by 37
“The particle-size distributions, while of a slightly larger size (and different material composition and shape) than that reported in human retrievals, were intended to resemble typical sizes that could be found in human retrievals (Lee et al. 1992, Shanbhag et al. 1994, Kobayashi et al. 1997).”
Background
Particle-induced SIRT1 downregulation promotes osteoclastogenesis and osteolysis through ER stress regulation.
Zhang, L., Bao, D.-M., Li, P., Lu, Z., Pang, L., Chen, Z., Guo, H., Gao, Z.-H., & Jin, Q. (2018) · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · doi:10.1016/j.biopha.2018.05.030 · Cited by 36
Immunotoxicity of Medical Devices
Rodgers, K., Klykken, P., Jacobs, J., Frondoza, C., Tomazic, V., & Zelikoff, J. (1997) · Toxicological Sciences · doi:10.1093/toxsci/36.1.1 · Cited by 36
Self-citation
Isolation, characterization and quantification of polyethylene wear debris from periprosthetic tissues around total joint replacements
Šlouf, M., Eklová, S., Kumstatova, J., Berger, S., Synková, H., Sosna, A., Pokorny, D., Špundová, M., & Entlicher, G. (2007) · doi:10.1016/j.wear.2006.11.005 · Cited by 35
Analysis of Polyethylene Particles Produced in Different Wear Conditions In Vitro
Calonius, O., & Saikko, V. (2002) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-200206000-00027 · Cited by 35
Aseptic Loosening of Pedicle Screw As a Result of Metal Wear Debris in a Pediatric Patient
Boțolin, S., Merritt, C., & Erickson, M. (2013) · Spine · doi:10.1097/brs.0b013e3182793e51 · Cited by 34
Bisphosphonate-modified gold nanoparticles: a useful vehicle to study the treatment of osteonecrosis of the femoral head
Fanord, F., Fairbairn, K., Kim, H. K. W., Garces, A. H., Bhethanabotla, V. R., & Gupta, V. K. (2010) · Nanotechnology · doi:10.1088/0957-4484/22/3/035102 · Cited by 41
The influence of lubricant on the morphology of ultra-high molecular weight polyethylene wear debris generated in laboratory tests
Besong, A. A., Tipper, J., Mathews, B., Ingham, E., Stone, M., & Fisher, J. (1999) · Proceedings of the Institution of mechanical engineers. Part H, journal of engineering in medicine · doi:10.1243/0954411991534870 · Cited by 34
Wear products of total hip arthroplasty: The case of polyethylene
Massin, P., & Achour, S. (2016) · Morphologie · doi:10.1016/j.morpho.2016.06.001 · Cited by 37
Wear simulation of reverse total shoulder arthroplasty systems: effect of glenosphere design.
Vaupel, Z. M., Baker, K., Kurdziel, M., & Wiater, J. (2012) · Journal of shoulder and elbow surgery · doi:10.1016/j.jse.2011.10.024 · Cited by 33
Transmission electron microscopy of intracellular particles of polyethylene from joint replacement prostheses: size distribution and cellular response.
Benz, E. B., Federman, M., Godleski, J. J., Bierbaum, B. E., Thornhill, T. S., & Spector, M. (2001) · Biomaterials · doi:10.1016/s0142-9612(01)00027-8 · Cited by 33
Current Trends in Improving of Artificial Joints Design and Technologies for Their Arthroplasty
Poliakov, A., Pakhaliuk, V., & Popov, V. L. (2020) · Frontiers in Mechanical Engineering · doi:10.3389/fmech.2020.00004 · Cited by 41
“The wear particle sizes for polyethylene were large in size (Lee et al., 1992; Shanbhag et al., 1994).”
Background
Role of fibroblasts and fibroblast‐derived growth factors in periprosthetic angiogenesis
Tunyogi-Csapó, M., Koreny, T., Vermes, C., Galante, J. O., Jacobs, J. J., & Glant, T. T. (2007) · Journal of Orthopaedic Research® · doi:10.1002/jor.20449 · Cited by 30
Self-citation
Titanium particles inhibit osteoblast adhesion to fibronectin‐coated substrates
Kwon, S., Takei, H., Pioletti, D., Lin, T., Ma, Q.-J., Akeson, W., Wood, D. J., & Sung, K.-L. P. (2000) · Journal of Orthopaedic Research · doi:10.1002/jor.1100180207 · Cited by 32
Effect of polyethylene wear on osteolysis in cementless primary total hip arthroplasty: minimal 5-year follow-up study.
Han, C., Choe, W., & Yoo, J. (1999) · Journal of Arthroplasty · doi:10.1016/s0883-5403(99)90227-9 · Cited by 32
Nano wear particles and the periprosthetic microenvironment in aseptic loosening induced osteolysis following joint arthroplasty
Xie, Y., Peng, Y., Fu, G., Jin, J., Wang, S., Li, M., Zheng, Q., Lyu, F., Deng, Z., & Ma, Y. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1275086 · Cited by 30
Characterization of polyethylene wear particle: The impact of methodology.
Schröder, C., Reinders, J., Zietz, C., Utzschneider, S., Bader, R., & Kretzer, J. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.07.039 · Cited by 31
Polymethylmethacrylate and titanium alloy particles activate peripheral monocytes during periprosthetic inflammation and osteolysis
Yang, S.-Y., Zhang, K., Bai, L., Song, Z., Yu, H.-Y., Mcqueen, D., & Wooley, P. (2011) · Journal of Orthopaedic Research · doi:10.1002/jor.21287 · Cited by 31
Isolation of polyacetal wear particles from periprosthetic tissue of isoelastic femoral stems.
Minovic, A., Milošev, I., Pišot, V., Cör, A., & Antolič, V. (2001) · Journal of Bone and Joint Surgery-british Volume · doi:10.1302/0301-620x.83b8.12087 · Cited by 31
Impact of microplastics and nanoplastics on human health: Mechanistic insights and exposure pathways
Rehman, M. F. U., Khan, M. M., & Khan, P. D. M. M. (2025) · Toxicology Letters · doi:10.1016/j.toxlet.2025.111769 · Cited by 31
Suppression of osteogenic activity by regulation of WNT and BMP signaling during titanium particle induced osteolysis.
Nam, J.-S., Sharma, A. R., Jagga, S., Lee, D.-H., Sharma, G., Nguyen, L., Lee, Y.-O.-H., Chang, J., Chakraborty, C., & Lee, S.-S. (2017) · Journal of Biomedical Materials Research. Part A · doi:10.1002/jbm.a.36004 · Cited by 28
Größe und Form kommerziell erhältlicher Polyethylenpartikel für In-vitro- und In-vivo-Versuche
von Knoch, M., Sprecher, C., Barden, B., Saxler, G., Löer, F., & Wimmer, M. (2004) · Zeitschrift für Orthopädie und ihre Grenzgebiete · doi:10.1055/s-2004-822589 · Cited by 28
Bone ingrowth in the presence of particulate polyethylene. Synergy between interface motion and particulate polyethylene in periprosthetic tissue response.
Bechtold, J., Kubic, V., & Soballe, K. (2002) · Journal of Bone and Joint Surgery-british Volume · doi:10.1302/0301-620x.84b6.12111 · Cited by 28
The growth of chondrocytes into a fibronectin-coated biodegradable scaffold
Bhati, R. S., Mukherjee, D. P., McCarthy, K. J., Rogers, S. H., Smith, D. F., & Shalaby, S. W. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(200107)56:1 · Cited by 86
Analysis of released products from oxidized ultra-high molecular weight polyethylene incubated with hydrogen peroxide and salt solutions.
Lee, A. W., Santerre, J., & Boynton, E. (2000) · Biomaterials · doi:10.1016/s0142-9612(99)00257-4 · Cited by 28
Comparison of UHMWPE particles in synovial fluid and tissues from failed THA.
Mabrey, J., Afsar-Keshmiri, A., McClung, G. A., Pember, M. A., Wooldridge, T. M., & Agrawal, C. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(2001)58:2 · Cited by 28
Fractures of a sandwich ceramic liner at ten year follow-up
Viste, A., Chouteau, J., Desmarchelier, R., & Fessy, M. (2012) · International Orthopaedics · doi:10.1007/s00264-011-1375-7 · Cited by 27
Comparison of Periprosthetic Tissue Digestion Methods for Ultra-High Molecular Weight Polyethylene Wear Debris Extraction
Baxter, R. M., Steinbeck, M., Tipper, J., Parvizi, J., Marcolongo, M., & Kurtz, S. (2009) · Journal of Biomedical Materials Research. Part B - Applied biomaterials · doi:10.1002/jbm.b.31416 · Cited by 27
“used 4 M KOH at 568C for 48 h to digest tissue.(28) Additionally, concentrated HNO3 was an effective digestion solution.”
Chemical stability of polyether urethanes versus polycarbonate urethanes
Tanzi, M. C., Mantovani, D., Petrini, P., Guidoin, R., & Laroche, G. (1997) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(19970915)36:4 · Cited by 159
Properties of tissue from around cemented joint implants with erosive and/or linear osteolysis.
Perry, M., Mortuza, F. Y., Ponsford, F. M., Elson, C. J., Atkins, R. M., & Learmonth, I. (1997) · Journal of Arthroplasty · doi:10.1016/s0883-5403(97)90140-6 · Cited by 27
Are periprosthetic tissue reactions observed after revision of total disc replacement comparable to the reactions observed after total hip or knee revision surgery?
Punt, I., Austen, S., Cleutjens, J., Kurtz, S., ten Broeke, R. T., van Rhijn, L. V., Willems, P., & van Ooij, A. (2012) · Spine · doi:10.1097/brs.0b013e3182154c22 · Cited by 26
Influence of gelatin and bovine serum lubricants on ultra-high molecular weight polyethylene wear debris generated in in vitro simulations
Bell, J., Besong, A. A., Tipper, J. L., Ingham, E., Wroblewski, B., Stone, M. H., & Fisher, J. (2000) · Proceedings of the Institution of mechanical engineers. Part H, journal of engineering in medicine · doi:10.1243/0954411001535543 · Cited by 26
A potential concern in total joint arthroplasty: systemic dissemination of wear debris.
Clark, C. (2000) · Journal of Bone and Joint Surgery. American volume · doi:10.2106/00004623-200004000-00001 · Cited by 26
Low-voltage scanning electron microscopic imaging of ultrahigh-molecular-weight polyethylene.
Pienkowski, D., Jacob, R. J., Hoglin, D. P., Saum, K., Kaufer, H., & Nicholls, P. J. (1995) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820291002 · Cited by 26
Zirconium and Niobium Affect Human Osteoblasts, Fibroblasts, and Lymphocytes in a Similar Manner to More Traditional Implant Alloy Metals
Hallab, N., Anderson, S., Caicedo, M., Jacobs, J., & Dean, S. (2006) · doi:10.1520/jai12817 · Cited by 26
Self-citation
Effect of reinforcement on wear debris of carbon nanofiber/high density polyethylene composites: Morphological study and quantitative analysis
Liu, T., Wood, W., Li, B., Lively, B., & Zhong, W. (2012) · doi:10.1016/j.wear.2012.07.010 · Cited by 25
Rate effects on the microindentation-based mechanical properties of oxidized, crosslinked, and highly crystalline ultrahigh-molecular-weight polyethylene.
Gilbert, J., & Merkhan, I. K. (2004) · Journal of Biomedical Materials Research. Part A · doi:10.1002/jbm.a.30196 · Cited by 25
Self-citation
Observations at the articular surface of hip prostheses: an analytical electron microscopy study on wear and corrosion.
Koerten, H. K., Onderwater, J., Koerten, E. W., Bernoski, F. P., & Nelissen, R. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(20010315)54:4 · Cited by 25
Prediction of plastic strains in ultra-high molecular weight polyethylene due to microscopic asperity interactions during sliding wear
Mcnie, C., Barton, D. C., Stone, M. H., & Fisher, J. (1998) · Proceedings of the Institution of mechanical engineers. Part H, journal of engineering in medicine · doi:10.1243/0954411981533818 · Cited by 25
Wear of artificial hip joint material
Watters, E. P. J., Spedding, P., Grimshaw, J., Duffy, J., & Spedding, R. (2005) · doi:10.1016/j.cej.2005.02.031 · Cited by 24
Friction reduction in total joint arthroplasty
Young, S. K., Lotito, M., & Keller, T. (1998) · doi:10.1016/s0043-1648(98)00275-0 · Cited by 24
Characterization of wear debris in total elbow arthroplasty.
Day, J., Baxter, R. M., Ramsey, M., Morrey, B., Connor, P., Kurtz, S., & Steinbeck, M. (2013) · Journal of shoulder and elbow surgery · doi:10.1016/j.jse.2013.02.001 · Cited by 23
The inhibition of neutrophil antibacterial activity by ultra-high molecular weight polyethylene particles.
Bernard, L., Vaudaux, P., Merle, C., Stern, R., Huggler, E., Lew, D., & Hoffmeyer, P. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.08.034 · Cited by 23
The formation of human auricular cartilage from microtic tissue: An in vivo study.
bin Ishak, M. F., Goh, B. S., Hui, C. K., Abdullah, A., bin Saim, L., bin Saim, A., & Idrus, R. (2015) · International Journal of Pediatric Otorhinolaryngology · doi:10.1016/j.ijporl.2015.06.034 · Cited by 22
“extrusion can be reduced if the rib cage cartilage graft or polymerbased ear scaffolds are enveloped under temporoparietal fascia flap (TPF) [2,3].”
Background
Wear debris from hip prostheses characterized by electron imaging
Topolovec, M., Milošev, I., Cör, A., & Bloebaum, R. (2013) · doi:10.2478/s11536-013-0156-7 · Cited by 22
“Ti-based particles originating from the femoral stem, ranging from 200 to 400 μm in size and from 10 to 20 μm in width, were isolated from periprosthetic tissue by an alkaline digestion method [26].”
BackgroundMethod
Risk Factors for Aseptic Loosening Following Total Hip Arthroplasty
Scott, J. E., Gordon, A. C., & Mark, J. R. (2012) · InTech eBooks · doi:10.5772/26975 · Cited by 16
Characteristics of hydroxyapatite coated titanium porous coatings on Ti-6Al-4V substrates by plasma sprayed method.
Yang, C.-Y., Chen, C., Chang, E., & Lee, T. M. (2007) · Journal of Biomedical Materials Research. Part B - Applied biomaterials · doi:10.1002/jbm.b.30750 · Cited by 22
Migration of polyethylene particles around nonloosened cemented femoral components from a total hip arthroplasty-an autopsy study.
Massin, P., Chappard, D., Flautre, B., & Hardouin, P. (2004) · Journal of Biomedical Materials Research. Part B - Applied biomaterials · doi:10.1002/jbm.b.30001 · Cited by 22
Heterogeneous nucleation of calcium phosphates on solid surfaces in aqueous solution
Wu, W., Zhuang, H., & Nancollas, G. H. (1997) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(199704)35:1 · Cited by 58
Postfailure compressive behavior of tibial trabecular bone in three anatomic directions
Keyak, J. H., Lee, I. Y., Nath, D. S., & Skinner, H. B. (1996) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(199607)31:3 · Cited by 37
Submicron–sized UHMWPE wear particle analysis from revised SB Charité III total disc replacements
Punt, I., Baxter, R. M., van Ooij, A., Willems, P., van Rhijn, L. V., Kurtz, S., & Steinbeck, M. (2011) · Acta Biomaterialia · doi:10.1016/j.actbio.2011.05.010 · Cited by 21
“53 μm) were comparable to previous studies [14, 17, 24, 42].”
Prevention of strain‐related osteopenia in aseptic loosening of hip prostheses using perioperative bisphosphonate
Goodship, A., Blunn, G., Green, J. R., & Coathup, M. (2008) · Journal of Orthopaedic Research · doi:10.1002/jor.20533 · Cited by 21
The Potential Role of Phagocytic Capacity in the Osteolytic Process Induced by Polyethylene Wear Particles
Fang, H.-W., Yang, C.-B., Chang, C.-H., Huang, C.-H., Liu, H.-L., & Fang, S. (2006) · Journal of International Medical Research · doi:10.1177/147323000603400611 · Cited by 21
Versagensanalyse von Knieendoprothesen
Bader, R., Mittelmeier, W., & Steinhauser, E. (2006) · Der Orthopade · doi:10.1007/s00132-006-0976-0 · Cited by 21
“Abriebpartikel können hinsichtlich Form, Größe, Verteilung, intra- oder extrazellulärem Vorkommen und Gewebereaktionen auch mittels REM, Spektroskopie und speziellen Partikelanalysegeräten untersucht werden [20].”
Background
Generation of narrowly distributed ultra-high-molecular-weight polyethylene particles by surface texturing techniques.
Fang, H.-W., Hsu, S. M., & Sengers, J. V. (2003) · Journal of Biomedical Materials Research. Part B - Applied biomaterials · doi:10.1002/jbm.b.10067 · Cited by 21
Biocompatibility: a biomechanical and biological concept in total hip replacement.
Learmonth, I. (2003) · The Surgeon · doi:10.1016/s1479-666x(03)80002-1 · Cited by 21
Effect of polymer molecular weight and addition of calcium stearate on response of MG63 osteoblast‐like cells to UHMWPE particles
Dean, D., Lohmann, C. H., Sylvia, V., Köster, G., Liu, Y., Schwartz, Z., & Boyan, B. (2001) · Journal of Orthopaedic Research · doi:10.1016/s0736-0266(00)00030-9 · Cited by 21

Authors: Shanbhag, A., Jacobs, J., Glant, T., Gilbert, J., Black, J., & Galante, J.
Affiliations: Rush University (US)
Venue: The Journal of Bone and Joint Surgery. British volume
Publisher: British Editorial Society of Bone & Joint Surgery
Published: 1994-01
Volume: 76-B
Issue: 1
Pages: 60-67
ISSN: 0301-620X (ISSN-L)
2044-5377
DOI: 10.1302/0301-620x.76b1.8300684
OpenAlex: W1914858881
Cited by: 387
References: 0
Citations by year: 2026: 1 · 2025: 4 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 9 · 2020: 3 · 2019: 3 · 2018: 7 · 2017: 5 · 2016: 5 · 2015: 4 · 2014: 12 · 2013: 11 · 2012: 9
FWCI: 26.08
Type: journal article
Language: en
Open access: closed
Licence: online.boneandjoint.org.uk/TDM (tdm)
Locations: Journal of Bone and Joint Surgery - British Volume (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Surgery › Orthopaedic implants and arthroplasty
Health Sciences › Medicine › Surgery › Orthopedic Infections and Treatments
Physical Sciences › Materials Science › Materials Chemistry › Titanium Alloys Microstructure and Properties
Keywords: wear debris, cementless total hip arthroplasty, revision hip arthroplasty, polyethylene wear particles, titanium alloys, interfacial membrane, particle size, implant failure, bone fragments, stainless steel particles, silicate particles
MeSH terms: Aged, Cementation, Female, Hip Joint, Hip Prosthesis, Humans, Male, Microscopy, Electron, Scanning, Middle Aged, Particle Size, Polyethylenes, Prosthesis Failure, Reoperation, Titanium, Spectroscopy, Fourier Transform Infrared

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Composition and morphology of wear debris in failed uncemented total hip replacement

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cited by

Metadata

Record

About these checks