Cited by 387Orthopaedic implants and arthroplastyOrthopedic Infections and TreatmentsTitanium Alloys Microstructure and Properties

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Composition and morphology of wear debris in failed uncemented total hip replacement

Shanbhag, AS, Jacobs, JJ, Glant, TT, Gilbert, JL, Black, J, Galante, JO·1994·The Journal of Bone and Joint Surgery. British volume

DOI 10.1302/0301-620x.76b1.8300684

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Abstract

Interfacial membranes collected at revision from 11 failed uncemented Ti-alloy total hip replacements were examined. Particles in the membranes were characterised by electron microscopy, microchemical spectroscopy and particle size analysis. Most were polyethylene and had a mean size of 0.53 micron +/- 0.3. They were similar to the particles seen in the base resin used in the manufacture of the acetabular implants. Relatively few titanium particles were seen. Fragments of bone, stainless steel and silicate were found in small amounts. Most of the polyethylene particles were too small to be seen by light microscopy. Electron microscopy and spectroscopic techniques are required to provide an accurate description of this debris.

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Bierbaum, B., D'Antonio, J., Capello, W., Manley, M., & Deshmukh, R. (2004) · doi:10.1007/978-3-7985-1968-8_5 · Cited by 4
Experimental study of drainage and granulation in response to the intra-articular injection of particles in rat knee joints
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Abriebverhalten von zementierten Hüftendoprothesen-Stielen*
Bader, R., Mittelmeier, W., Steinhauser, E., Brehm, P., Brem, R., Tübel, J., P. Choungthong, Winklmair, D., Schmitt, M., & Holzwarth, U. (2005) · doi:10.3139/120.100648 · Cited by 3
Versagensursachen primärer Implantationen
Baumann, B., Fuerst, M., Kirschner, S., Lohmann, C., Nuechtern, J., Rader, C., Ruether, W., Seifert, J., & Zustin, J. (2008) · doi:10.1007/978-3-540-75649-1_2 · Cited by 3
Total Hip Arthroplasty
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Biological Response to Particulate Debris from Nonmetallic Orthopedic Implants
Pappas, M., Schmidt, C., Shanbhag, A. S., Whiteside, T., Rubash, H., & Herndon, J. (1996) · doi:10.1007/978-1-4757-2487-5_6 · Cited by 3
Self-citation
Synergistic effects of mixed TiAlV and polyethylene wear particles on TNFα response in THP-1 macrophages / Synergistische Effekte gemischter TiAlV- und Polyethylen-Abriebpartikel auf die TNFα-Antwort in THP-1 Makrophagen
Baumann, B., Rolf, O., Jakob, F., Goebel, S., Sterner, T., Eulert, J., & Rader, C. (2006) · Biomedizinische Technik. Biomedical engineering · doi:10.1515/bmt.2006.070 · Cited by 2
Biology of Foreign Bodies: Tolerance, Osteolysis, and Allergy
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Dynamic Viscoelasticity of Ultrahigh-Molecular-Weight Polyethylene After Ethylene Oxide Gas or Gamma-Irradiated Sterilization
Kawate, K., Ohmura, T., Hiyoshi, N., Nakajima, H., Natsume, Y., Teranishi, T., Tamai, S., & Nanzai, Y. (1999) · doi:10.1007/978-4-431-68529-6_9 · Cited by 2
Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics
Wang, H., Wu, J., Wang, B., Qin, H., Fan, L., Wang, Y.-H., & He, B. (2023) · International Journal of Endocrinology · doi:10.1155/2023/9373043 · Cited by 1
“After trauma, osteoclasts are activated under the action of various infammatory factors and proliferate in large numbers [19, 20], thus cooperating with immune cells to release a large number of proin-fammatory factors [21], especially tumor necrosis factor-α (TNF-α ), interleukin-1 (IL-1), and…”
Background
Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint Replacement
von Skrbensky, G., Mühlbacher, K., Benca, E., Kolb, A., Windhager, R., Reischl, G., & Reinisch, G. (2019) · Italian National Conference on Sensors · doi:10.3390/s19173751 · Cited by 1
Steel Contamination of Biomedical Titanium Alloys during Hot Isostatic Pressing Treatments
Marin, E., Lanzutti, A., & Fedrizzi, L. (2014) · Metallography Microstructure and Analysis · doi:10.1007/s13632-014-0123-y · Cited by 1
“Fragments from machining tools or sandblasting particles [29], impurities in the autoclave steam moisture during sterilization [30], inadequate surface preparation/passivation [31], the presence of bone fragments during surgery [32] and, in general, every step between raw material production and implantation adds a sm…”
Background
A Quantitative Model of Wear Loss Based on On-Line Visual Ferrograph
Wang, C.-H., Yuan, W.-Y., Dong, G., & Mao, J. (2013) · doi:10.4028/www.scientific.net/amm.330.338 · Cited by 1
“The wear particles in the lubricant are satisfied some inherent distribution [6-11].”
Background
The John Charnley Award: An Accurate and Sensitive Method to Separate, Display, and Characterize Wear Debris: Part 1: Polyethylene Particles
Billi, F., Benya, P., Kavanaugh, A., Adams, J. S., Ebramzadeh, E., & Mckellop, H. (2012) · Clinical Orthopaedics and Related Research · doi:10.1007/s11999-011-2057-x · Cited by 1
“The first protocol, originally developed at our research center in the 1990s [8], has been widely used [24, 31, 46, 48] and is hereinafter referred to as the NaOH protocol.”
Cytokines and Mediators in Physiologic and Pathologic Bone Resorption
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Foreign Body Granulomatous Response to Particulate Bony Debris
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“Tiny calcium phosphaterich particles, remnants of drilling, reaming and curettage or bone-implant interfacial abrasion products, constitute another type of periprosthetic debris (49).”
Background

Authors: Shanbhag, A., Jacobs, J., Glant, T., Gilbert, J., Black, J., & Galante, J.
Affiliations: Rush University (US)
Venue: The Journal of Bone and Joint Surgery. British volume
Publisher: British Editorial Society of Bone & Joint Surgery
Published: 1994-01
Volume: 76-B
Issue: 1
Pages: 60-67
ISSN: 0301-620X (ISSN-L)
2044-5377
DOI: 10.1302/0301-620x.76b1.8300684
OpenAlex: W1914858881
Cited by: 387
References: 0
Citations by year: 2026: 1 · 2025: 4 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 9 · 2020: 3 · 2019: 3 · 2018: 7 · 2017: 5 · 2016: 5 · 2015: 4 · 2014: 12 · 2013: 11 · 2012: 9
FWCI: 26.08
Type: journal article
Language: en
Open access: closed
Licence: online.boneandjoint.org.uk/TDM (tdm)
Locations: Journal of Bone and Joint Surgery - British Volume (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Surgery › Orthopaedic implants and arthroplasty
Health Sciences › Medicine › Surgery › Orthopedic Infections and Treatments
Physical Sciences › Materials Science › Materials Chemistry › Titanium Alloys Microstructure and Properties
Keywords: wear debris, cementless total hip arthroplasty, revision hip arthroplasty, polyethylene wear particles, titanium alloys, interfacial membrane, particle size, implant failure, bone fragments, stainless steel particles, silicate particles
MeSH terms: Aged, Cementation, Female, Hip Joint, Hip Prosthesis, Humans, Male, Microscopy, Electron, Scanning, Middle Aged, Particle Size, Polyethylenes, Prosthesis Failure, Reoperation, Titanium, Spectroscopy, Fourier Transform Infrared

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Composition and morphology of wear debris in failed uncemented total hip replacement

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