The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Antibiotic prophylaxis for wound infections in total joint arthroplasty: A SYSTEMATIC REVIEW
Open accessAbstract
We reviewed systematically the published evidence on the effectiveness of antibiotic prophylaxis for the reduction of wound infection in patients undergoing total hip and total knee replacement. Publications were identified using the Cochrane Library, MEDLINE, EMBASE and CINAHL databases. We also contacted authors to identify unpublished trials. We included randomised controlled trials which compared any prophylaxis with none, the administration of systemic antibiotics with that of those in cement, cephalosporins with glycopeptides, cephalosporins with penicillin-derivatives, and second-generation with first-generation cephalosporins. A total of 26 studies (11 343 participants) met the inclusion criteria. Methodological quality was variable. In a meta-analysis of seven studies (3065 participants) antibiotic prophylaxis reduced the absolute risk of wound infection by 8% and the relative risk by 81% compared with no prophylaxis (p < 0.00001). No other comparison showed a significant difference in clinical effect. Antibiotic prophylaxis should be routine in joint replacement but the choice of agent should be made on the basis of cost and local availability.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763
Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease
(1959) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/22.4.719 · Cited by 14,689
Moher, D., Cook, D. J., Eastwood, S., Olkin, I., Rennie, D., & Stroup, D. F. (1999) · The Lancet · doi:10.1016/s0140-6736(99)04149-5 · Cited by 4,826
Zimmerli, W., Trampuz, A., & Ochsner, P. E. (2004) · New England Journal of Medicine · doi:10.1056/nejmra040181 · Cited by 3,116
Verhagen, A. P., de Vet, H. C. W., de Bie, R. A., Kessels, A. G. H., Boers, M., Bouter, L. M., & Knipschild, P. G. (1998) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(98)00131-0 · Cited by 2,379
Language bias in randomised controlled trials published in English and German
Egger, M., Zellweger-Zähner, T., Schneider, M., Junker, C., Lengeler, C., & Antes, G. (1997) · The Lancet · doi:10.1016/s0140-6736(97)02419-7 · Cited by 1,028
Bratzler, D. W. (2005) · Archives of Surgery · doi:10.1001/archsurg.140.2.174 · Cited by 578
Hill, C., Mazas, F., Flamant, R., & Evrard, J. (1981) · The Lancet · doi:10.1016/s0140-6736(81)92678-7 · Cited by 371
Cloxacillin in the Prophylaxis of Postoperative Infections of the Hip
ERICSON, C., LIDGREN, L., & LINDBERG, L. (1973) · The Journal of Bone & Joint Surgery · doi:10.2106/00004623-197355040-00015 · Cited by 174
Cited by
Bone substitutes in orthopaedic surgery: from basic science to clinical practice
Campana, V., Milano, G., Pagano, E., Barba, M., Cicione, C., Salonna, G., Lattanzi, W., & Logroscino, G. (2014) · Journal of Materials Science: Materials in Medicine · doi:10.1007/s10856-014-5240-2 · Cited by 1,117
Metadata
- Authors
- AlBuhairan, B., Hind, D., & Hutchinson, A.
- Venue
- The Journal of Bone and Joint Surgery. British volume
- Published
- 2008-07
- Volume
- 90-B
- Issue
- 7
- Pages
- 915-919
- ISSN
- 0301-620X (ISSN-L)
- 2044-5377
- OpenAlex
- W2187199690
- Cited by
- 284
- References
- 19
- FWCI
- 9.37
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Antibiotic prophylaxis for wound infections in total joint arthroplasty: A SYSTEMATIC REVIEW. https://app.cochat.ai/papers/10.1302/0301-620x.90b7.20498
- The paper
- AlBuhairan, B., Hind, D., & Hutchinson, A. (2008). Antibiotic prophylaxis for wound infections in total joint arthroplasty: A SYSTEMATIC REVIEW. The Journal of Bone and Joint Surgery. British volume. https://doi.org/10.1302/0301-620x.90b7.20498
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
