Tuberculosis and HIV Infection: Epidemiology, Immunology, and Treatment
Open accessAbstract
Tuberculosis and HIV have combined to present a major threat to global public health. Each disease has a negative effect on the other, and mortality in patients with both tuberculosis and HIV is higher than that caused by either condition alone. In regions such as sub-Saharan Africa, as many as a third or more of all patients with tuberculosis have concomitant HIV infection. In urban centers in developed nations, HIV co-infection may also be quite common. Treatment of latent tuberculosis infection in persons with HIV is successful in preventing many cases of active disease, and newer ultra-short course regimens, such as those consisting of 2 months of rifampin and pyrazinamide, should aid in this effort. Diagnosis and treatment of active tuberculosis in HIV-infected patients may be difficult. Although treatment of active tuberculosis is generally successful in patients with HIV, drug interactions between anti-tuberculosis medications and antiretrovirals often complicate the matter, and expert guidance should be sought for proper management.
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Diagnosis of tuberculous lymphadenitis by FNAC, microbiological methods and PCR: a comparative study
Aljafari, A. S., Khalil, E. A. G., Elsiddig, K. E., El Hag, I. A., Ibrahim, M. E., Elsafi, M. E. M. O., Hussein, A. M., Elkhidir, I. M., Sulaiman, G. S., & Elhassan, A. M. (2004) · Cytopathology · doi:10.1111/j.1365-2303.2003.00119.x · Cited by 103 · see citing works
- Authors
- Schluger, N. W., & Burzynski, J.
- Affiliations
- Columbia University Irving Medical Center (US)
- Government of New York City (US)
- Corresponding author
- Schluger, Neil W.
- Venue
- HIV Clinical Trials
- Publisher
- Informa UK Limited
- Published
- 2001-08
- Volume
- 2
- Issue
- 4
- Pages
- 356-365
- ISSN
- 1528-4336 (ISSN-L)
- 1945-5771
- OpenAlex
- W2169841915
- Semantic Scholar
- e2c38f4240cb7212d0253154280ba79534511345
- Cited by
- 18
- References
- 70
- Citations by year
- 2015: 1 · 2014: 1 · 2013: 2 · 2012: 1
- FWCI
- 1.26
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- HIV Clinical Trials (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Health Sciences › Medicine › Surgery › Infectious Diseases and Tuberculosis
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- tuberculosis, HIV infection, tuberculosis-HIV coinfection, latent tuberculosis infection, active tuberculosis, rifampicin, pyrazinamide, drug interactions, antiretroviral drugs, antitubercular agents, tuberculosis immunology, tuberculosis epidemiology, mortality
- MeSH terms
- Antibiotics, Antitubercular, Humans, Rifampin, Tuberculosis, Pulmonary, AIDS-Related Opportunistic Infections
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