Cardiotrophin-1 Is an Osteoclast-Derived Stimulus of Bone Formation Required for Normal Bone Remodeling

Interleukin‐6 deficient mice are protected from bone loss caused by estrogen depletion.

Poli, V., Balena, R. F., Fattori, E., Markatos, A., Yamamoto, M., Tanaka, H., Ciliberto, G., Rodan, G. A., & Costantini, F. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06368.x · Cited by 745

Osteoclast-derived activity in the coupling of bone formation to resorption

Martin, T. J., & Sims, N. A. (2005) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2004.12.004 · Cited by 661

Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death

Ware, C. B., Horowitz, M. C., Renshaw, B. R., Hunt, J. S., Liggitt, D., Koblar, S. A., Gliniak, B., McKenna, H. J., Papayannopoulou, T., Thoma, B., et al. (1995) · Development · doi:10.1242/dev.121.5.1283 · Cited by 589

Osteotropic Agents Regulate the Expression of Osteoclast Differentiation Factor and Osteoprotegerin in Osteoblastic Stromal Cells

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Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors.

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Use of Type I Collagen Green Fluorescent Protein Transgenes to Identify Subpopulations of Cells at Different Stages of the Osteoblast Lineage

Kalajzić, I., Kalajzić, Ž., Kaliterna, M., Gronowicz, G., Clark, S. H., Lichtler, A. C., & Rowe, D. W. (2002) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2002.17.1.15 · Cited by 392

Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone

Calvi, L. M., Sims, N. A., Hunzelman, J. L., Knight, M. C., Giovannetti, A., Saxton, J. M., Kronenberg, H. M., Baron, R., & Schipani, E. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11296 · Cited by 388

Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males

Sims, N. A., Dupont, S., Krust, A., Clément-Lacroix, P., Minet, D., Resche-Rigon, M., Gaillard-Kelly, M., & Baron, R. (2002) · Bone · doi:10.1016/s8756-3282(01)00643-3 · Cited by 354

Role of the CCAAT Enhancer Binding Proteins (C/EBPs) in Adipocyte Differentiation

Lane, M. D., Tang, Q.-Q., & Jiang, M.-S. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1885 · Cited by 281

Interleukin‐6 modulates production of T lymphocyte–derived cytokines in antigen‐induced arthritis and drives inflammation‐induced osteoclastogenesis

Wong, P. K. K., Quinn, J. M. W., Sims, N. A., van Nieuwenhuijze, A. E. M., Campbell, I. K., & Wicks, I. P. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21537 · Cited by 271

The IL6-like Cytokine Family: Role and Biomarker Potential in Breast Cancer

Martínez-Pérez, C., Kay, C., Meehan, J., Gray, M., Dixon, J. M., & Turnbull, A. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11111073 · Cited by 28

Caspase inhibition by cardiotrophin‐1 prevents neuronal death in vivo and in vitro

Peng, H., Sola, A., Moore, J. E., & Wen, T. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22269 · Cited by 26

Beyond resorption: osteoclasts as drivers of bone formation

Xiang, Q., Li, L., Ji, W., Gawlitta, D., Walboomers, X. F., & van den Beucken, J. J. J. P. (2024) · Cell Regeneration · doi:10.1186/s13619-024-00205-x · Cited by 29

The Cells of Bone and Their Interactions

Ansari, N., & Sims, N. A. (2019) · Handbook of experimental pharmacology · doi:10.1007/164_2019_343 · Cited by 29

Spatial Organization of Osteoclastic Coupling Factors and Their Receptors at Human Bone Remodeling Sites

Borggaard, X. G., Nielsen, M. H., Delaissé, J., Andreasen, C. M., & Andersen, T. L. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.896841 · Cited by 25

Positive and Negative Regulators of Sclerostin Expression

Iwamoto, R., Koide, M., Udagawa, N., & Kobayashi, Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094895 · Cited by 27

Stüve–Wiedemann syndrome and related bent bone dysplasias

Akawi, N. A., Ali, B. R., & Al‐Gazali, L. I. (2012) · Clinical Genetics · doi:10.1111/j.1399-0004.2012.01852.x · Cited by 24

Prostaglandin E2 acts via bone marrow macrophages to block PTH-stimulated osteoblast differentiation in vitro

Choudhary, S., Blackwell, K. A., Voznesensky, O. S., Roy, A. D., & Pilbeam, C. C. (2013) · Bone · doi:10.1016/j.bone.2013.04.017 · Cited by 24

Estrogen regulation of myokines that enhance osteoclast differentiation and activity

Norton, A., Thieu, K., Baumann, C., Lowe, D., & Mansky, K. (2022) · Scientific Reports · doi:10.1038/s41598-022-19438-4 · Cited by 25

Bone Marrow Microvasculature

Prisby, R. D. (2020) · Comprehensive physiology · doi:10.1002/cphy.c190009 · Cited by 30

Decline in calcitonin receptor expression in osteocytes with age

Gooi, J. H., Chia, L. Y., Walsh, N. C., Karsdal, M. A., Quinn, J. M. W., Martin, T. J., & Sims, N. A. (2014) · Journal of Endocrinology · doi:10.1530/joe-13-0524 · Cited by 22

Friend or Foe? Essential Roles of Osteoclast in Maintaining Skeletal Health

Wang, H., Yang, G., Xiao, Y., Luo, G., Li, G., & Li, Z. (2020) · BioMed Research International · doi:10.1155/2020/4791786 · Cited by 23

Bone, a Secondary Growth Site of Breast and Prostate Carcinomas: Role of Osteocytes

Maroni, P., & Bendinelli, P. (2020) · Cancers · doi:10.3390/cancers12071812 · Cited by 21

Marine derived natural products for osteoporosis

Senthilkumar, K., Venkatesan, J., & Kim, S. (2014) · Biomedicine & Preventive Nutrition · doi:10.1016/j.bionut.2013.12.005 · Cited by 21

Osteoclast Biology: Regulation of Formation and Function

Choi, Y., Faccio, R., Teitelbaum, S. L., & Takayanagi, H. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800571-2.00004-9 · Cited by 21

A bone substitute with high affinity for vitamin D‐binding protein―relationship with niche of osteoclasts

Ikeda, T., Kasai, M., Tatsukawa, E., Kamitakahara, M., Shibata, Y., Yokoi, T., Nemoto, T., & Ioku, K. (2013) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12180 · Cited by 20

Oncostatin M regulates osteogenic differentiation of murine adipose-derived mesenchymal progenitor cells through a PKCdelta-dependent mechanism

Smyth, D. C., Takenaka, S., Yeung, C., & Richards, C. D. (2015) · Cell and Tissue Research · doi:10.1007/s00441-014-2099-y · Cited by 20

Tributyltin induces distinct effects on cortical and trabecular bone in female C57Bl/6J mice

Watt, J. D., Baker, A. H., Meeks, B., Pajevic, P. D., Morgan, E. F., Gerstenfeld, L. C., & Schlezinger, J. J. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26495 · Cited by 19

OSM is overexpressed in knee osteoarthritis and Notch signaling is involved in the effects of OSM on MC3T3-E1 cell proliferation and differentiation

Ni, J., YUAN, X., YAO, Q., & PENG, L. (2015) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2015.2168 · Cited by 19

The multi-faceted role of retinoid X receptor in bone remodeling

Menéndez-Gutierrez, M. P., & Ricote, M. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2458-4 · Cited by 18

Stimulation of Osteoclast Formation by Oncostatin M and the Role of WNT16 as a Negative Feedback Regulator

de Souza, P. C., Henning, P., & Lerner, U. H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063287 · Cited by 17

Osteoclast-derived coupling factors: origins and state-of-play Louis V Avioli lecture, ASBMR 2023

Sims, N. A. (2024) · Journal of Bone and Mineral Research · doi:10.1093/jbmr/zjae110 · Cited by 19

STAT3 Hyperactivation Due to SOCS3 Deletion in Murine Osteocytes Accentuates Responses to Exercise- and Load-Induced Bone Formation

McGregor, N. E., Walker, E. C., Chan, A. S. M., Poulton, I. J., Cho, H., Windahl, S. H., & Sims, N. A. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4484 · Cited by 18

Regulation of Sclerostin Expression by Paracrine and Endocrine Factors

Sims, N. A., & Chia, L. Y. (2011) · Clinical Reviews in Bone and Mineral Metabolism · doi:10.1007/s12018-011-9121-7 · Cited by 18

Topography-based implants for bone regeneration: Design, biological mechanism, and therapeutics

Guo, W., Yang, Z., Liu, F., Song, J., Yang, W., Li, Y., Hu, W., & Wang, K. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102066 · Cited by 18

Basics of Bone Biology

Rauner, M., Stein, N., & Hofbauer, L. C. (2011) · Springer eBooks · doi:10.1007/978-3-7091-0520-7_1 · Cited by 16

Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-stimulated cAMP Signaling in Murine Osteoblasts

Choudhary, S., Goetjen, A., Estus, T., Jacome-Galarza, C. E., Aguila, H. L., Lorenzo, J. A., & Pilbeam, C. C. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.686576 · Cited by 16

G-CSF Receptor Deletion Amplifies Cortical Bone Dysfunction in Mice With STAT3 Hyperactivation in Osteocytes

Isojima, T., Walker, E. C., Poulton, I. J., McGregor, N. E., Wicks, I. P., Gooi, J. H., Martin, T. J., & Sims, N. A. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4654 · Cited by 14

Brief exposure to full length parathyroid hormone-related protein (PTHrP) causes persistent generation of cyclic AMP through an endocytosis-dependent mechanism

Ho, P. W. M., Chan, A. S. M., Pavlos, N. J., Sims, N. A., & Martin, T. J. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.113627 · Cited by 13

Roles of Slit Ligands and Their Roundabout (Robo) Family of Receptors in Bone Remodeling

Niimi, T. (2020) · Advances in experimental medicine and biology · doi:10.1007/5584_2020_586 · Cited by 11

The osteoblast lineage

Sims, N. A., & Martin, T. J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814841-9.00004-x · Cited by 11

Overcoming barriers confronting application of protein therapeutics in bone fracture healing

Czech, T., & Oyewumi, M. O. (2020) · Drug Delivery and Translational Research · doi:10.1007/s13346-020-00829-x · Cited by 11

Interleukin-11, an IL-6-like cytokine

Hook, C., & Kuprash, D. V. (2011) · Molecular Biology · doi:10.1134/s0026893311010055 · Cited by 11

Role of osteoclasts in heterotopic ossification enhanced by fibrodysplasia ossificans progressiva-related activin-like kinase 2 mutation in mice

Kawao, N., Yano, M., Tamura, Y., Okumoto, K., Okada, K., & Kaji, H. (2015) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-015-0701-3 · Cited by 11

Interactions Among Osteoblasts, Osteoclasts, and Other Cells in Bone

Martin, T. J., Sims, N. A., & Quinn, J. M. W. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-375670-1.10008-1 · Cited by 11

Mice Lacking the Calcitonin Receptor Do Not Display Improved Bone Healing

Appelt, J., Tsitsilonis, S., Otto, E., Jahn, D., Köhli, P., Baranowsky, A., Jiang, S., Fuchs, M., Bucher, C. H., Duda, G. N., et al. (2021) · Cells · doi:10.3390/cells10092304 · Cited by 10

Coupling of bone formation and resorption

Sims, N. A., & Martin, T. J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814841-9.00010-5 · Cited by 11

Coupling: The Influences of Immune and Bone Cells

Sims, N. A., Martin, T. J., & Quinn, J. M. W. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800571-2.00010-4 · Cited by 9

Osteoclast Secretes Stage‐Specific Key Molecules for Modulating Osteoclast–Osteoblast Communication

Fu, Y., Shi, S., Wu, J., Yuan, Z., Wang, L. F., Nie, H., Zhang, Z., Wu, X., Chen, Y., Ti, H., et al. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.31484 · Cited by 9

Local regulators of bone

Sims, N. A., & Lorenzo, J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814841-9.00050-6 · Cited by 7

Loss of Cbl–PI3K interaction in mice prevents significant bone loss following ovariectomy

Adapala, N. S., Holland, D., Scanlon, V. M., Barbe, M. F., Langdon, W. Y., Tsygankov, A. Y., Lorenzo, J. A., & Sanjay, A. (2014) · Bone · doi:10.1016/j.bone.2014.06.013 · Cited by 8

Dynamic imaging of the effect of mesenchymal stem cells on osteoclast precursor cell chemotaxis for bone defects in the mouse skull

Abe, T., Sumi, K., Kunimatsu, R., Oki, N., Tsuka, Y., Nakajima, K., & Tanimoto, K. (2018) · Journal of Dental Sciences · doi:10.1016/j.jds.2018.08.001 · Cited by 8

Targeting osteoclast-derived DPP4 alleviates inflammation-mediated ectopic bone formation in ankylosing spondylitis

Lee, S. H., Lee, K. H., Kim, D. H., Jeon, C., Whangbo, M., Jo, H.-R., Youn, J., Lee, C., Choi, S. H., Park, Y., et al. (2025) · Arthritis Research & Therapy · doi:10.1186/s13075-025-03474-2 · Cited by 8

Cellular Contributors to Bone Homeostasis

Rauner, M., Jähn, K., Hemmatian, H., Colditz, J., & Goettsch, C. (2020) · Contemporary cardiology · doi:10.1007/978-3-030-46725-8_16 · Cited by 6

Bone marrow osteoprogenitors are depleted whereas osteoblasts are expanded independent of the osteogenic vasculature in response to zoledronic acid

Hughes, R., Chen, X., Hunter, K. D., Hobbs, J. K., Holen, I., & Brown, N. J. (2019) · The FASEB Journal · doi:10.1096/fj.201900553rr · Cited by 7

Testing Bone Formation Induction by Calvarial Injection Assay in vivo

McGregor, N. E., Poulton, I. J., Walker, E. C., & Sims, N. A. (2020) · BIO-PROTOCOL · doi:10.21769/bioprotoc.3560 · Cited by 7

Aspects of intercellular communication in bone and implications in therapy

Martin, T. J. (2021) · Bone · doi:10.1016/j.bone.2021.116148 · Cited by 6

Bone niche and bone metastases

Han, Y., & Kang, Y. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821666-8.00041-4 · Cited by 6

Skeletal physiology

Sinclair, C., Birch, H. L., Smith, R. K. W., & Goodship, A. E. (2013) · Elsevier eBooks · doi:10.1016/b978-0-7020-4771-8.00008-9 · Cited by 6

Protease-activated receptor-2 promotes osteogenesis in skeletal mesenchymal stem cells at the expense of adipogenesis: Involvement of interleukin-6

Sanaei, R., Kularathna, P. K., Taghavi, N., Hooper, J. D., Pagel, C. N., & Mackie, E. J. (2021) · Bone Reports · doi:10.1016/j.bonr.2021.101113 · Cited by 6

Le vieillissement osseux : les nouveaux acteurs de communication intercellulaire

Funck‐Brentano, T., & Cohen-Solal, M. E. (2010) · Médecine & longévité · doi:10.1016/j.mlong.2010.05.001 · Cited by 6

Bone remodeling biology

Kahla, R. B., & Barkaoui, A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-88467-9.00002-3 · Cited by 6

Integrating Endocrine and Paracrine Influences on Bone; Lessons From Parathyroid Hormone and Parathyroid Hormone-Related Protein

Martin, T. J., & Sims, N. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804182-6.00017-4 · Cited by 5

Inhibitor of protein kinase N3 suppresses excessive bone resorption in ovariectomized mice

Uehara, S., Mukai, H., Yamashita, T., Koide, M., Murakami, K., Udagawa, N., & Kobayashi, Y. (2022) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-021-01296-1 · Cited by 5

Allogeneic yet major histocompatibility complex-matched bone marrow transplantation in mice results in an impairment of osteoblasts and a significantly reduced trabecular bone

Osterberg, A., Engelmann, R., & Müller‐Hilke, B. (2017) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-017-0859-y · Cited by 4

Stimulation of Osteogenesis in Bone Defects Implanted with Biodegradable Hydroxyapatite Composed of Rod-Shaped Particles under Mechanical Unloading

Ikeda, T., Gonda, Y., Tatsukawa, E., Shibata, Y., Kamitakahara, M., Okuda, T., Yonezawa, I., Kurosawa, H., & Ioku, K. (2012) · ACTA HISTOCHEMICA ET CYTOCHEMICA · doi:10.1267/ahc.12012 · Cited by 4

Basic Principles of Bone Cell Biology

Martin, T. J., Ng, K. W., & Sims, N. A. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-415784-2.00002-6 · Cited by 4

Dimensionality reduction of chaos by feedbacks and periodic forcing is a source of natural climate change

Salmon, P. (2024) · Climate Dynamics · doi:10.1007/s00382-024-07191-5 · Cited by 3

Breast Cancer Metastases to Bone: Role of the Microenvironment

Jenna, E., & Светлана, В. (2011) · InTech eBooks · doi:10.5772/21741 · Cited by 3

Effect of intermittent administration of teriparatide on the mechanical and histological changes in bone grafted with β‑tricalcium phosphate using a rabbit bone defect model

Komatsu, J., Nagura, N., Iwase, H., Igarashi, M., Ohbayashi, O., Nagaoka, I., & Kaneko, K. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.5424 · Cited by 3

Basic Aspects of Osteoclast Differentiation and Function

Alesi, N., Charles, J. F., & Nakamura, M. C. (2020) · Contemporary Endocrinology · doi:10.1007/978-3-319-69287-6_2 · Cited by 3

Integrating Endocrine and Paracrine Influences on Bone

Martin, T. J., & Sims, N. A. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-387829-8.00004-4 · Cited by 3

Beyond resorption-driven coupling: a multi-layered framework for osteoclast–osteoblast communication and its therapeutic consequences

Qiu, H., Liu, S., Jiang, Y., Lai, Y., Lin, Q., & Huang, A. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1821292 · Cited by 2

Basics of Bone Biology

Rauner, M., & Hofbauer, L. C. (2016) · Springer eBooks · doi:10.1007/978-3-319-34238-2_1 · Cited by 2

Image-Based Histological Evaluation of Scaffold-Free 3D Osteoblast Cultures

Eggert, S., Tuebel, J., Foehr, P., Kuntz, L. A., Obermeier, A., Marthen, C., Große, C. U., & Burgkart, R. (2017) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk2040042 · Cited by 2

Mechanism Reversing Bone Resorption to Formation During Bone Remodeling

Delaissé, J., Andersen, T. L., Kristensen, H. B., & Jensen, P. R. (2021) · Springer eBooks · doi:10.1007/978-981-16-5613-2_6 · Cited by 2

Development of Novel Models for Studying Osteoclasts

Thudium, C. S. (2014) · Lund University Publications (Lund University) · Cited by 2

Role of Interleukins on Physiological and Pathological Bone Resorption and Bone Formation: Effects by Cytokines in The IL-6 and IL-10 Families

Lerner, U. H. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11553-3 · Cited by 2

Characteristics of osteoclasts at different developmental stages and therapeutic strategies

Fan, Z., Shuai, F., Xie, Y., Lin, Y., Yao, Y., Han, X., & Yin, Y. (2026) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2026.118703 · Cited by 1

JAK1/STAT3 signalling in cortical bone development, growth and maintenance

Koh, N. Y. Y., Maes, C., & Sims, N. A. (2026) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2026.120129 · Cited by 1

Osteoclast-derived DEL1 promotes pathological bone formation in ankylosing spondylitis by regulating RUNX2 expression in osteoblasts

Lee, S., Jeon, C., Kim, D., Jo, H.-R., Ko, E., Youn, J., Lee, S., Choi, S. H., Park, Y. W., Jo, S., et al. (2026) · Differentiation · doi:10.1016/j.diff.2026.100962 · Cited by 1

Understanding of stem cells in bone biology and translation into clinical applications

Liu, P., Fan, Z., & Wang, S. (2010) · Frontiers in Biology · doi:10.1007/s11515-010-0930-8 · Cited by 1

Mechanism of interleukin-6 cytokine family in bone metastasis of lung cancer and prospects for its application

Huang, J., Zhang, Q., Yang, Y., Wang, W., & Cai, J. (2025) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2025.189398 · Cited by 1

Role of Oxidative Stress in Bone Ageing

Portal‐Núñez, S., & Esbrit, P. (2012) · Springer eBooks · doi:10.1007/978-1-4614-6166-1_6 · Cited by 1

Aplicación de la Cardiotrofina en un modelo experimental de diabetes mellitus

Jiménez-González, M., Prósper, F., & Barajas, M. (2012) · Deposito Adademico Digital Universidad De Navarra (University of Navarra)

Síndrome de la Respuesta Inflamatoria Sistémica en la Isquemia/Reperfusión y Trasplante Renal. Efectividad de la Cardiotrofina‐1

Cenador, M. B. G. (2011) · Gredos (University of Salamanca) · doi:10.14201/gredos.108971

Differentiation of osteoblasts to osteocytes in 3D type I collagen gels - a novel tool to study osteocyte responses to mechanical loading

Scully, N. E. E. (2015) · ORCA Online Research @Cardiff (Cardiff University)

Molecular and structural patterns of guided bone regeneration (GBR). Experimental studies on the role of GBR membrane and bone substitute materials

Elgali, I. (2015) · Gothenburg University Publications Electronic Archive (Gothenburg University)

Cardiotrophin-1, an antiinflammatory cytokine; is there a therapeutic role in orthotopic liver transplantation?

Fukuhara, S., & Leitman, I. M. (2012) · Journal of Surgical Research · doi:10.1016/j.jss.2012.08.003

Die Rolle von Calcitonin und seines Rezeptors im Knochenstoffwechsel - Untersuchungen an gentechnisch modifizierten Mausmodellen

Amling, M. (2010)

Reflections on Development of Concepts of Intercellular Communication in Bone

Martin, T. J. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-415853-5.00004-2

Efecto protector de la cardiotrofina-1 en la fibrosis tubulointersticial y glomerulonefritis

Perretta‐Tejedor, N. (2017) · Gredos (University of Salamanca) · doi:10.14201/gredos.137128

Cardiotrophin-1 signaling essential for normal mouse bone resorption and formation

(2009) · Nature Reviews Rheumatology · doi:10.1038/ncprheum1001

Bone Remodeling – Clinical Evaluation

Nuti, R. (2023) · Endocrinology · doi:10.1007/978-3-030-19632-5_6-1 · Cited by 1

Bone cells: Osteoblast/osteoclast/osteocyte

Ucci, A., & Rucci, N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13825-6.00158-8

Beyond bone: the emerging role of osteoclasts in immune regulation, leukemia development and following myeloablative therapy

Kuek, V., Kotecha, R. S., & Cheung, L. C. (2025) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2025.2595220

Integrating endocrine and paracrine influences on bone: lessons from parathyroid hormone and parathyroid hormone-related protein

Martin, T. J., & Sims, N. A. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-13683-2.00004-9

Rôles respectifs des sous fonctions du ER alpha impliquées dans les effets bénéfiques des œstrogènes sur l'os : du squelette appendiculaire aux maxillaires

Vinel, A. (2015) · theses.fr (ABES) · doi:10.70675/01d5a665z7499z4ef9za360zc2f10dc7b7bf

CSF1R+ Macrophages and Osteoclasts Are Essential for Limb Bone Development During Embryogenesis

Ma, F., Zhou, R., Rosin, M., & Rosin, J. M. (2026) · Journal of Developmental Biology · doi:10.3390/jdb14030031

Cardiotrophin-1 signaling essential for normal mouse bone resorption and formation

(2009) · Nature Reviews Rheumatology · doi:10.1038/ncprheum1001

Cardiotrophin-1 regulates osteoclast and osteoblast function in a manner distinct from other gp130 cytokines

Sims, N. A., Walker, E. C., Quinn, J. M. W., Allen, E. A., Saleh, H., & Martin, T. J. (2006) · Bone · doi:10.1016/j.bone.2006.01.121

Cthrc1 Is a Positive Regulator of Osteoblastic Bone Formation

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