Sims, Natalie A.

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

Winkler, I. G., Sims, N. A., Pettit, A. R., Barbier, V., Nowlan, B., Helwani, F., Poulton, I. J., van Rooijen, N., Alexander, K. A., Raggatt, L. J., et al. (2010) · Blood

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 801

Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption

Sims, N. A., & Gooi, J. H. (2008) · Seminars in Cell & Developmental Biology

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 513

Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment

Walkley, C. R., Shea, J. M., Sims, N. A., Purton, L. E., & Orkin, S. H. (2007) · Cell

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 424

Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone

Calvi, L. M., Sims, N. A., Hunzelman, J. L., Knight, M. C., Giovannetti, A., Saxton, J. M., Kronenberg, H. M., Baron, R., & Schipani, E. (2001) · Journal of Clinical Investigation

Bone Metabolism and DiseasesParathyroid Disorders and Treatments

Cited by 388

Osteoprotegerin Reduces Osteoclast Numbers and Prevents Bone Erosion in Collagen-Induced Arthritis

Romas, E., Sims, N. A., Hards, D. K., Lindsay, M., Quinn, J. W. M., Ryan, P. F. J., Dunstan, C. R., Martin, T. J., & Gillespie, M. T. (2002) · The American Journal of Pathology

Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies

Cited by 368

Quantifying the osteocyte network in the human skeleton

Buenzli, P. R., & Sims, N. A. (2015) · Bone

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 300

Osteoclasts Provide Coupling Signals to Osteoblast Lineage Cells Through Multiple Mechanisms

Sims, N. A., & Martin, T. J. (2020) · Annual Review of Physiology

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 286

Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

Widjaja, A. A., Lim, W.-W., Viswanathan, S., Chothani, S., Corden, B., Dasan, C. M., Goh, J. W. T., Lim, R., Singh, B. K., Tan, J., et al. (2024) · Nature

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 238

RANKL/OPG; Critical role in bone physiology

Martin, T. J., & Sims, N. A. (2015) · Reviews in Endocrine and Metabolic Disorders

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 213

EphrinB2 Regulation by PTH and PTHrP Revealed by Molecular Profiling in Differentiating Osteoblasts

Allan, E. H., Häusler, K. D., Wei, T., Gooi, J. H., Quinn, J. M., Crimeen-Irwin, B., Pompolo, S., Sims, N. A., Gillespie, M. T., Onyia, J. E., et al. (2008) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesParathyroid Disorders and Treatments

Cited by 199

Cardiotrophin-1 Is an Osteoclast-Derived Stimulus of Bone Formation Required for Normal Bone Remodeling

Walker, E. C., McGregor, N. E., Poulton, I. J., Pompolo, S., Allan, E. H., Quinn, J. M., Gillespie, M. T., Martin, T. J., & Sims, N. A. (2008) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 190

Coupling Signals between the Osteoclast and Osteoblast: How are Messages Transmitted between These Temporary Visitors to the Bone Surface?

Sims, N. A., & Martin, T. J. (2015) · Frontiers in Endocrinology

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 184

The Heat Shock Protein 90 Inhibitor, 17-Allylamino-17-demethoxygeldanamycin, Enhances Osteoclast Formation and Potentiates Bone Metastasis of a Human Breast Cancer Cell Line

Price, J. T., Quinn, J. M. W., Sims, N. A., Vieusseux, J., Waldeck, K., Docherty, S. E., Myers, D., Nakamura, A., Waltham, M. C., Gillespie, M. T., et al. (2005) · Cancer Research

Heat shock proteins researchBone Metabolism and Diseases

Cited by 142

Calcitonin impairs the anabolic effect of PTH in young rats and stimulates expression of sclerostin by osteocytes

Gooi, J. H., Pompolo, S., Karsdal, M. A., Kulkarni, N. H., Kalajzic, I., McAhren, S. H. M., Han, B., Onyia, J. E., Ho, P. W. M., Gillespie, M. T., et al. (2010) · Bone

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 117

Dissociation of Bone Resorption and Bone Formation in Adult Mice with a Non-Functional V-ATPase in Osteoclasts Leads to Increased Bone Strength

Henriksen, K., Flores, C., Thomsen, J. S., Brüel, A.-M., Thudium, C. S., Neutzsky-Wulff, A. V., Langenbach, G. E. J., Sims, N., Askmyr, M., Martin, T. J., et al. (2011) · PLoS ONE

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 77

Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

Vrahnas, C., Blank, M., Dite, T. A., Tatarczuch, L., Ansari, N., Crimeen-Irwin, B., Nguyen, H., Forwood, M. R., Hu, Y., Ikegame, M., et al. (2019) · Nature Communications

Bone Metabolism and DiseasesAlkaline Phosphatase Research Studies

Cited by 70

Isolation and gene expression of haematopoietic-cell-free preparations of highly purified murine osteocytes

Chia, L. Y., Walsh, N. C., Martin, T. J., & Sims, N. A. (2015) · Bone

Bone Metabolism and DiseasesBone and Dental Protein Studies

Cited by 42

Decline in calcitonin receptor expression in osteocytes with age

Gooi, J. H., Chia, L. Y., Walsh, N. C., Karsdal, M. A., Quinn, J. M. W., Martin, T. J., & Sims, N. A. (2014) · Journal of Endocrinology

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 22

Calcitonin Physiology, Saved by a Lysophospholipid

Martin, T. J., & Sims, N. A. (2015) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesParathyroid Disorders and Treatments

Cited by 21