The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Retinal layer segmentation of macular OCT images using boundary classification
Open accessAbstract
Optical coherence tomography (OCT) has proven to be an essential imaging modality for ophthalmology and is proving to be very important in neurology. OCT enables high resolution imaging of the retina, both at the optic nerve head and the macula. Macular retinal layer thicknesses provide useful diagnostic information and have been shown to correlate well with measures of disease severity in several diseases. Since manual segmentation of these layers is time consuming and prone to bias, automatic segmentation methods are critical for full utilization of this technology. In this work, we build a random forest classifier to segment eight retinal layers in macular cube images acquired by OCT. The random forest classifier learns the boundary pixels between layers, producing an accurate probability map for each boundary, which is then processed to finalize the boundaries. Using this algorithm, we can accurately segment the entire retina contained in the macular cube to an accuracy of at least 4.3 microns for any of the nine boundaries. Experiments were carried out on both healthy and multiple sclerosis subjects, with no difference in the accuracy of our algorithm found between the groups.
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Cited by
Artificial intelligence in retina
Schmidt-Erfurth, U., Sadeghipour, A., Gerendas, B. S., Waldstein, S. M., & Bogunović, H. (2018) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2018.07.004 · Cited by 779
Chiu, S. J., Allingham, M. J., Mettu, P. S., Cousins, S. W., Izatt, J. A., & Farsiu, S. (2015) · Biomedical Optics Express · doi:10.1364/boe.6.001172 · Cited by 377
Structured layer surface segmentation for retina OCT using fully convolutional regression networks
He, Y., Carass, A., Liu, Y., Jedynak, B. M., Solomon, S. D., Saidha, S., Calabresi, P. A., & Prince, J. L. (2021) · Medical Image Analysis · doi:10.1016/j.media.2020.101856 · Cited by 104
Self-citationSotirchos, E. S., Filippatou, A., Fitzgerald, K. C., Salama, S., Pardo, S., Wang, J., Ogbuokiri, E., Cowley, N. J., Pellegrini, N., Murphy, O. C., et al. (2020) · Multiple Sclerosis Journal · doi:10.1177/1352458519864928 · Cited by 98
Self-citationHe, Y., Carass, A., Solomon, S. D., Saidha, S., Calabresi, P. A., & Prince, J. L. (2019) · Data in Brief · doi:10.1016/j.dib.2018.12.073 · Cited by 90
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Metadata
- Authors
- Lang, A., Carass, A., Hauser, M., Sotirchos, E. S., Calabresi, P. A., Ying, H. S., & Prince, J. L.
- Venue
- Biomedical Optics Express
- Publisher
- Optica Publishing Group
- Published
- 2013-06-14
- Volume
- 4
- Issue
- 7
- Pages
- 1133
- ISSN
- 2156-7085 (ISSN-L)
- OpenAlex
- W2038850290
- Cited by
- 310
- References
- 38
- FWCI
- 11.88
- Type
- journal article
- Language
- en
- Open access
- gold
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