The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
On the fundamental imaging-depth limit in two-photon microscopy
Abstract
We have analyzed how the maximal imaging depth of two-photon microscopy in scattering samples depends on properties of the sample and the imaging system. We find that the imaging depth increases with increasing numerical aperture and staining inhomogeneity and with decreasing excitation-pulse duration and scattering anisotropy factor, but is ultimately limited by near-surface fluorescence with slight improvements possible using special detection strategies.
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A review of the optical properties of biological tissues
Cheong, W. F., Prahl, S. A., & Welch, A. J. (1990) · IEEE Journal of Quantum Electronics · doi:10.1109/3.64354 · Cited by 2,530
Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex
Trachtenberg, J. T., Chen, B. E., Knott, G. W., Feng, G., Sanes, J. R., Welker, E., & Svoboda, K. (2002) · Nature · doi:10.1038/nature01273 · Cited by 1,927
Long-term dendritic spine stability in the adult cortex
Grutzendler, J., Kasthuri, N., & Gan, W.-B. (2002) · Nature · doi:10.1038/nature01276 · Cited by 1,198
Kleinfeld, D., Mitra, P. P., Helmchen, F., & Denk, W. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.26.15741 · Cited by 832
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Cited by
Richardson, D. S., & Lichtman, J. W. (2015) · Cell · doi:10.1016/j.cell.2015.06.067 · Cited by 1,095
Two-Photon Microscopy as a Tool to Study Blood Flow and Neurovascular Coupling in the Rodent Brain
Shih, A. Y., Driscoll, J. D., Drew, P. J., Nishimura, N., Schaffer, C. B., & Kleinfeld, D. (2012) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2011.196 · Cited by 458
In vivo two-photon microscopy to 1.6-mm depth in mouse cortex
Kobat, D., Horton, N. G., & Xu, C. (2011) · Journal of Biomedical Optics · doi:10.1117/1.3646209 · Cited by 417
Wide field-of-view, multi-region, two-photon imaging of neuronal activity in the mammalian brain
Stirman, J. N., Smith, I. T., Kudenov, M. W., & Smith, S. L. (2016) · Nature Biotechnology · doi:10.1038/nbt.3594 · Cited by 331
Two-photon excitation microscopy for the study of living cells and tissues
Benninger, R. K. P., & Piston, D. W. (2013) · Current Protocols in Cell Biology · doi:10.1002/0471143030.cb0411s59 · Cited by 311
Metadata
- Authors
- Theer, P., & Denk, W.
- Venue
- Journal of the Optical Society of America A
- Publisher
- Optica Publishing Group
- Published
- 2006-12-01
- Volume
- 23
- Issue
- 12
- Pages
- 3139
- ISSN
- 1084-7529 (ISSN-L)
- 1520-8532
- OpenAlex
- W2141354231
- Cited by
- 399
- References
- 4
- FWCI
- 7.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- Theer, P., & Denk, W. (2006). On the fundamental imaging-depth limit in two-photon microscopy. Journal of the Optical Society of America A. https://doi.org/10.1364/josaa.23.003139
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