Full range characterization of the Raman spectra of organs in a murine model
Open accessAbstract
Raman spectroscopy is a minimally-invasive optical technique with great potential for in vivo cancer detection and disease diagnosis. However, there is no systematic study of the Raman spectra from different organs to date. We measured and characterized the Raman spectra eighteen naïve mouse organs in a broad frequency range of 700 to 3100 cm⁻¹. The peaks of generic proteins and lipids appeared in Raman spectra of all organs. Some organs like bone, teeth, brain and lung had unique Raman peaks. The autofluorescence was strong in liver, spleen, heart, and kidney. These results suggest that organ specific Raman probe design and specific data processing strategies are required in order to get the most useful information.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
SERS imaging can suffer from poor signal-to-noise ratio because Raman bands from biological tissues can overlap with those of the Raman reporter molecule.
“this imaging technique can suffer from poor signal-to-noise ratio, as the complexity of biological tissues can lead to overlapping of Raman bands from tissues and the Raman reporter molecule utilized.”
From Design and evaluation of Raman reporters for the Raman-silent region (2022) · cites this paper as [13]
The Raman-silent region (1750-2750 cm−1) is a spectral window where Raman bands from biological molecules and tissues are minimized.
“a spectral window where Raman bands from biological molecules and tissues are minimized 13, 14”
From Design and evaluation of Raman reporters for the Raman-silent region (2022) · cites this paper as [13]
Cites
Reference database of Raman spectra of biological molecules
De Gelder, J., De Gussem, K., Vandenabeele, P., & Moens, L. (2007) · Journal of Raman Spectroscopy · doi:10.1002/jrs.1734 · Cited by 1,425 · see citing works
Prospects forin vivoRaman spectroscopy
Hanlon, E. B., Manoharan, R., Koo, T.-W., Shafer‐Peltier, K., Motz, J. T., Fitzmaurice, M., Kramer, J. R., Itzkan, I., Dasari, R. R., & Feld, M. S. (2000) · Physics in Medicine and Biology · doi:10.1088/0031-9155/45/2/201 · Cited by 895 · see citing works
Near‐infrared Raman spectroscopy for optical diagnosis of lung cancer
Huang, Z., McWilliams, A. M., Lui, H., McLean, D. I., Lam, S. C., & Zeng, H. (2003) · International Journal of Cancer · doi:10.1002/ijc.11500 · Cited by 822 · see citing works
Self-citationAutomated Autofluorescence Background Subtraction Algorithm for Biomedical Raman Spectroscopy
Zhao, J., Lui, H., McLean, D. I., & Zeng, H. (2007) · Applied Spectroscopy · doi:10.1366/000370207782597003 · Cited by 816 · see citing works
Self-citationRaman spectroscopy for identification of epithelial cancers
Stone, N., Kendall, C. A., Smith, J., Crow, P., & Barr, H. (2003) · Faraday Discussions · doi:10.1039/b304992b · Cited by 770 · see citing works
Micro-Raman Spectroscopy Detects Individual Neoplastic and Normal Hematopoietic Cells
Chan, J. W., Taylor, D. S., Zwerdling, T., Lane, S. M., Ihara, K., & Huser, T. R. (2005) · Biophysical Journal · doi:10.1529/biophysj.105.066761 · Cited by 679 · see citing works
Diagnosing breast cancer by using Raman spectroscopy
Haka, A. S., Shafer‐Peltier, K., Fitzmaurice, M., Crowe, J. P., Dasari, R. R., & Feld, M. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501390102 · Cited by 633 · see citing works
Near infrared Raman spectra of human brain lipids
Krafft, C., Neudert, L., Simat, T. J., & Salzer, R. (2004) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2004.11.017 · Cited by 604 · see citing works
Near‐infrared Raman spectroscopy for the classification of epithelial pre‐cancers and cancers
Stone, N., Kendall, C., Shepherd, N., Crow, P., & Barr, H. (2002) · Journal of Raman Spectroscopy · doi:10.1002/jrs.882 · Cited by 472 · see citing works
Combined In Vivo Confocal Raman Spectroscopy and Confocal Microscopy of Human Skin
Caspers, P. J., Lucassen, G. W., & Puppels, G. J. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)74501-9 · Cited by 446 · see citing works
Raman spectroscopy: elucidation of biochemical changes in carcinogenesis of oesophagus
Shetty, G., Kendall, C. A., Shepherd, N. A., Stone, N., & Barr, H. (2006) · British Journal of Cancer · doi:10.1038/sj.bjc.6603102 · Cited by 446 · see citing works
Raman Spectroscopy of Normal and Diseased Human Breast Tissues
Frank, C. J., McCreery, R. L., & Redd, D. C. B. (1995) · Analytical Chemistry · doi:10.1021/ac00101a001 · Cited by 404 · see citing works
Micro‐Raman spectroscopy used to identify and grade human skin pilomatrixoma
Cheng, W., Liu, M., Liu, H., & Lin, S. (2005) · Microscopy Research and Technique · doi:10.1002/jemt.20229 · Cited by 371 · see citing works
Structure of Water, Proteins, and Lipids in Intact Human Skin, Hair, and Nail
Gniadecka, M., Nielsen, O. F., Christensen, D. H., & Wulf, H. C. (1998) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1998.00146.x · Cited by 351 · see citing works
Discriminating Basal Cell Carcinoma from its Surrounding Tissue by Raman Spectroscopy
Schut, T. C. B., Caspers, P. J., Puppels, G. J., Nijssen, A., Heule, F., NEUMANN, M. H. A. M., & Hayes, D. P. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01807.x · Cited by 347 · see citing works
Malini, R., Venkatakrishna, K., Kurien, J., Pai, K. M., Rao, L., Kartha, V. B., & Krishna, C. M. (2005) · Biopolymers · doi:10.1002/bip.20398 · Cited by 328 · see citing works
Sha, M. Y., Xu, H., Natan, M. J., & Cromer, R. (2008) · Journal of the American Chemical Society · doi:10.1021/ja804494m · Cited by 320 · see citing works
Discrimination between ricin and sulphur mustard toxicity in vitro using Raman spectroscopy
Notingher, I., Green, C. A., Dyer, C. D., Perkins, E. A., Hopkins, N., Lindsay, C., & Hench, L. L. (2004) · Journal of The Royal Society Interface · doi:10.1098/rsif.2004.0008 · Cited by 291 · see citing works
Raman Spectroscopy Detects Biochemical Changes Due to Proliferation in Mammalian Cell Cultures
Short, K. W., Carpenter, S. G., Freyer, J. P., & Mourant, J. R. (2005) · Biophysical Journal · doi:10.1529/biophysj.103.038604 · Cited by 287 · see citing works
Tissue Raman Spectroscopy for the Study of Radiation Damage: Brain Irradiation of Mice
Lakshmi, R. J., Kartha, V. B., Krishna, C. M., Solomon, J. G. R., Ullas, G., & Devi, P. U. (2002) · Radiation Research · doi:10.1667/0033-7587(2002)157[0175:trsfts]2.0.co;2 · Cited by 252 · see citing works
Teh, S. K., Zheng, W., Ho, K. Y., Teh, M., Yeoh, K. G., & Huang, Z. (2008) · British Journal of Cancer · doi:10.1038/sj.bjc.6604176 · Cited by 230 · see citing works
In vivo nonmelanoma skin cancer diagnosis using Raman microspectroscopy
Lieber, C. A., Majumder, S. K., Ellis, D. L., Billheimer, D. D., & Mahadevan-Jansen, A. M. (2008) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20653 · Cited by 218 · see citing works
Carden, A., Rajachar, R. M., Morris, M. D., & Kohn, D. H. (2003) · Calcified Tissue International · doi:10.1007/s00223-002-1039-0 · Cited by 201 · see citing works
The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro
Crow, P., Stone, N., Kendall, C. A., Uff, J., Farmer, J. A. M., Barr, H., & Wright, M. (2003) · British Journal of Cancer · doi:10.1038/sj.bjc.6601059 · Cited by 189 · see citing works
Raman Spectroscopic Imaging Markers for Fatigue-Related Microdamage in Bovine Bone
Timlin, J. A., Carden, A., Morris, M. D., Rajachar, R. M., & Kohn, D. H. (2000) · Analytical Chemistry · doi:10.1021/ac9913560 · Cited by 187 · see citing works
Detection of Meningioma in Dura Mater by Raman Spectroscopy
Koljenović, S., Schut, T. C. B., Vincent, A. J. P. E., Kros, J. M., & Puppels, G. J. (2005) · Analytical Chemistry · doi:10.1021/ac0512599 · Cited by 175 · see citing works
Silveira, L., Sathaiah, S., Zângaro, R. A., Pacheco, M. T. T., Chavantes, M. C., & Pasqualucci, C. A. (2002) · Lasers in Surgery and Medicine · doi:10.1002/lsm.10053 · Cited by 152 · see citing works
Short, M. A., Lam, S. C., McWilliams, A. M., Zhao, J., Lui, H., & Zeng, H. (2008) · Optics Letters · doi:10.1364/ol.33.000711 · Cited by 148 · see citing works
Self-citationHuang, Z., Lui, H., McLean, D. I., Korbelik, M., & Zeng, H. (2005) · Photochemistry and Photobiology · doi:10.1562/2005-02-24-ra-449 · Cited by 141 · see citing works
Self-citationHuang, Z., McWilliams, A. M., Lam, S. C., English, J. C., McLean, D. I., Lui, H., & Zeng, H. (2003) · International Journal of Oncology · doi:10.3892/ijo.23.3.649 · Cited by 128 · see citing works
Self-citationTowards oncological application of Raman spectroscopy
Nijssen, A., Koljenović, S., Schut, T. C. B., Caspers, P. J., & Puppels, G. J. (2009) · Journal of Biophotonics · doi:10.1002/jbio.200810055 · Cited by 113 · see citing works
Kast, R. E., Serhatkulu, G. K., Cao, A., Pandya, A. K., Dai, H., Thakur, J. S., Naik, V. M., Naik, R., Klein, M. D., Auner, G. W., et al. (2007) · Biopolymers · doi:10.1002/bip.20899 · Cited by 106 · see citing works
Raman Spectroscopy, the Sleeping Giant in Structural Biology, Awakes
CAREY, P. R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.38.26625 · Cited by 105 · see citing works
Yavorskyy, A., Hernández-Santana, A., McCarthy, G., & McMahon, G. P. (2008) · The Analyst · doi:10.1039/b716791a · Cited by 104 · see citing works
1064 nm near‐infrared multichannel Raman spectroscopy of fresh human lung tissues
Min, Y., Yamamoto, T., Kohda, E., Ito, T., & Hamaguchi, H. (2005) · Journal of Raman Spectroscopy · doi:10.1002/jrs.1280 · Cited by 100 · see citing works
Raman Chemical Imaging of Breast Tissue
Kline, N. J., & Treado, P. J. (1997) · Journal of Raman Spectroscopy · doi:10.1002/(sici)1097-4555(199702)28:2/3 · Cited by 94 · see citing works
Deng, J., Wei, Q., Zhang, M. H., Wang, Y. Z., & Li, Y. (2005) · Journal of Raman Spectroscopy · doi:10.1002/jrs.1301 · Cited by 91 · see citing works
Study of normal colorectal tissue by FT-Raman spectroscopy
Andrade, P. O., Bitar, R. A., Yassoyama, K., Martinho, H. D. S., Santo, A. M. D. E., Bruno, P. M., & Martin, A. A. (2006) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-006-0819-1 · Cited by 86 · see citing works
Measurement of hemoglobin oxygen saturation using Raman microspectroscopy and 532-nm excitation
Filho, I. P. T., Terner, J., Pittman, R. N., Proffitt, E. K., & Ward, K. R. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00025.2008 · Cited by 85 · see citing works
Optical Spectroscopy for Noninvasive Monitoring of Stem Cell Differentiation
Downes, A. R., Mouras, R., & Elfick, A. P. D. (2010) · BioMed Research International · doi:10.1155/2010/101864 · Cited by 83 · see citing works
A multimodal spectroscopy system for real-time disease diagnosis
Šćepanović, O. R., Volynskaya, Z. I., Kong, C.-R., Galindo, L. H., Dasari, R. R., & Feld, M. S. (2009) · Review of Scientific Instruments · doi:10.1063/1.3117832 · Cited by 65 · see citing works
Surface-enhanced Raman scattering detection of lysophosphatidic acid
Seballos, L., Zhang, J. Z., & Sutphen, R. (2005) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-005-0097-3 · Cited by 48 · see citing works
Raman Spectroscopy: A Novel Experimental Approach to Evaluating Renal Tumours
Bensalah, K., Fleureau, J., Rolland, D., Lavastre, O., Rioux-Leclercq, N. C., Guillé, F., Patard, J., Senhadji, L., & de Crevoisier, R. (2010) · European Urology · doi:10.1016/j.eururo.2010.06.002 · Cited by 44 · see citing works
Detecting Temporal and Spatial Effects of Epithelial Cancers with Raman Spectroscopy
Keller, M. D., Kanter, E. M., Lieber, C. A., Majumder, S. K., Hutchings, J. C., Ellis, D. L., Beaven, R. B., Stone, N., & Mahadevan-Jansen, A. M. (2008) · Disease Markers · doi:10.1155/2008/230307 · Cited by 43 · see citing works
Wang, H., Huang, N., Zhao, J., Lui, H., Korbelik, M., & Zeng, H. (2010) · Journal of Raman Spectroscopy · doi:10.1002/jrs.2677 · Cited by 42 · see citing works
Self-citationEvaluation of Pancreatic Cancer With Raman Spectroscopy in a Mouse Model
Pandya, A. K., Serhatkulu, G. K., Cao, A., Kast, R. E., Dai, H., Rabah, R. M., Poulik, J. M., Banerjee, S., Naik, R., Adsay, V. N., et al. (2008) · Pancreas · doi:10.1097/mpa.0b013e31815a3f1c · Cited by 41 · see citing works
Surface-Enhanced Raman Scattering of Rat Tissues
Aydin, Ö. F., Kahraman, M., Kılıç, E., & Çulha, M. (2009) · Applied Spectroscopy · doi:10.1366/000370209788559647 · Cited by 34 · see citing works
An overview on applications of optical spectroscopy in cervical cancers
Chilakapati, M., Sockalingum, G. D., Vidyasagar, M., Manfait, M., Fernanades, D., Vadhiraja, B., & Maheedhar, K. (2008) · Journal of Cancer Research and Therapeutics · doi:10.4103/0973-1482.39602 · Cited by 33 · see citing works
Shen, A., Zhang, B., Ping, J., Xie, W. L., Donfack, P., Baek, S., Zhou, X., Wang, H., Materny, A., & Hu, J. (2008) · Journal of Raman Spectroscopy · doi:10.1002/jrs.2163 · Cited by 25 · see citing works
Self-citationRaman Microscopy of Freeze‐dried Mouse Eyeball‐slice in Conjunction with the “in vivo Cryotechnique”
Terada, N., Ohno, N., Saitoh, S., Fujii, Y., Ohguro, H., & Ohno, S. (2007) · Microscopy Research and Technique · doi:10.1002/jemt.20449 · Cited by 15 · see citing works
Flagged first, then by citations
1 of the 51 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Raman Spectroscopy of Biological Tissues
Talari, A. C. S., Movasaghi, Z., Rehman, S., & Rehman, I. U. (2014) · Applied Spectroscopy Reviews · doi:10.1080/05704928.2014.923902 · Cited by 754 · see citing works
Raman spectroscopy: techniques and applications in the life sciences
Shipp, D. W., Sinjab, F., & Notingher, I. (2017) · Advances in Optics and Photonics · doi:10.1364/aop.9.000315 · Cited by 398 · see citing works
High-specific-power flexible transition metal dichalcogenide solar cells
Nazif, K. N., Daus, A., Hong, J., Lee, N., Vaziri, S., Kumar, A., Nitta, F. U., Chen, M., Kananian, S., Islam, R., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-27195-7 · Cited by 223 · see citing works
Raman technologies in cancer diagnostics
Austin, L. A., Osseiran, S., & Evans, C. L. (2015) · The Analyst · doi:10.1039/c5an01786f · Cited by 182 · see citing works
Raman Spectroscopy: Guiding Light for the Extracellular Matrix
Bergholt, M. S., Serio, A., & Albro, M. B. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00303 · Cited by 143 · see citing works
Saletnik, A., Saletnik, B. A., & Puchalski, C. (2021) · Molecules · doi:10.3390/molecules26061537 · Cited by 143 · see citing works
Real‐time in vivo cancer diagnosis using raman spectroscopy
Wang, W., Zhao, J., Short, M., & Zeng, H. (2014) · Journal of Biophotonics · doi:10.1002/jbio.201400026 · Cited by 123 · see citing works
Self-citationLatka, I., Dochow, S., Krafft, C., Dietzek, B., & Popp, J. (2013) · Laser & Photonics Review · doi:10.1002/lpor.201200049 · Cited by 93 · see citing works
In situ identification of environmental microorganisms with Raman spectroscopy
Cui, D., Kong, L., Wang, Y., Zhu, Y., & Zhang, C. (2022) · Environmental Science and Ecotechnology · doi:10.1016/j.ese.2022.100187 · Cited by 82 · see citing works
Raman spectroscopy based analysis of milk using random forest classification
Amjad, A., Ullah, R., Khan, S., Bilal, M., & Khan, A. (2018) · Vibrational Spectroscopy · doi:10.1016/j.vibspec.2018.09.003 · Cited by 80 · see citing works
Surface-enhanced Raman scattering (SERS) spectroscopy for prostate cancer diagnosis: A review
Haroon, M. Y., Tahir, M. W., Nawaz, H., Majeed, M. I., & Al‐Saadi, A. A. (2021) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2021.102690 · Cited by 68 · see citing works
Aubertin, K., Trinh, V. Q., Jermyn, M., Baksic, P., Grosset, A., Desroches, J., St‐Arnaud, K., Birlea, M., Vladoiu, M. C., Latour, M., et al. (2018) · British Journal of Urology · doi:10.1111/bju.14199 · Cited by 69 · see citing works
Pena, A., Chen, X., Pence, I. J., Bornschlögl, T., Jeong, S., Grégoire, S., Luengo, G. S., Hallegot, P., Obeidy, P., Feizpour, A., et al. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.03.003 · Cited by 65 · see citing works
Galiana, A. F., Bibikova, O., Pedersen, S. V., & Stevens, M. M. (2023) · Advanced Materials · doi:10.1002/adma.202210807 · Cited by 63 · see citing works
Paidi, S. K., Rizwan, A., Zheng, C., Cheng, M., Glunde, K., & Barman, I. (2016) · Cancer Research · doi:10.1158/0008-5472.can-16-1862 · Cited by 61 · see citing works
PVDF Fibers Modification by Nitrate Salts Doping
Sobola, D. S., Kaspar, P., Částková, K., Dallaev, R., Papěž, N., Sedlák, P., Trčka, T., Orudzhev, F. F., Kaštyl, J., Weiser, A., et al. (2021) · Polymers · doi:10.3390/polym13152439 · Cited by 60 · see citing works
Monitoring glycosylation metabolism in brain and breast cancer by Raman imaging
Kopec, M., Imiela, A., & Abramczyk, H. (2019) · Scientific Reports · doi:10.1038/s41598-018-36622-7 · Cited by 60 · see citing works
Wang, K., Chen, L., Ma, X., Ma, L., Chou, K. C., Cao, Y., Khan, I. U. H., Gölz, G., & Lu, X. (2020) · Applied and Environmental Microbiology · doi:10.1128/aem.00924-20 · Cited by 55 · see citing works
Piloto, A. M. L., Ribeiro, D. S. M., Rodrigues, S. S. M., Santos, J. L. M., Sampaio, P., & Sales, M. G. F. (2022) · Microchimica Acta · doi:10.1007/s00604-022-05230-8 · Cited by 50 · see citing works
Abramczyk, H., Surmacki, J. M., Kopeć, M., Olejnik, A. K., Kaufman‐Szymczyk, A., & Fabianowska‐Majewska, K. (2016) · The Analyst · doi:10.1039/c6an00859c · Cited by 44 · see citing works
Brożek-Płuska, B., Kopeć, M., & Abramczyk, H. (2016) · Analytical Methods · doi:10.1039/c6ay02559e · Cited by 42 · see citing works
Veliz, L., Cooper, T. T., Grenier‐Pleau, I., Abraham, S. A., Gomes, J., Pasternak, S., Dauber, B., Postovit, L.-M. M., Lajoie, G., & Lagugné‐Labarthet, F. (2024) · ACS Sensors · doi:10.1021/acssensors.3c01908 · Cited by 41 · see citing works
Discrimination of liver malignancies with 1064 nm dispersive Raman spectroscopy
Pence, I. J., Patil, C. A., Lieber, C. A., & Mahadevan-Jansen, A. M. (2015) · Biomedical Optics Express · doi:10.1364/boe.6.002724 · Cited by 38 · see citing works
Strobbia, P., Cupil‐Garcia, V., Crawford, B. M., Fales, A. M., Pfefer, T. J., Liu, Y., Maiwald, M., Sumpf, B., & Vo‐Dinh, T. (2021) · Theranostics · doi:10.7150/thno.53101 · Cited by 37 · see citing works
Liu, C., Qi, J., Lü, J., Wang, S., Wu, C., Shih, W., & Larin, K. V. (2014) · Journal of Innovative Optical Health Sciences · doi:10.1142/s1793545815500066 · Cited by 35 · see citing works
Silicon nitride laser cladding: A feasible technique to improve the biological response of zirconia
Marin, E., Zanocco, M., Boschetto, F., Santini, M., Zhu, W., Adachi, T., Ohgitani, E., McEntire, B. J., Bal, B. S., & Pezzotti, G. (2020) · Materials & Design · doi:10.1016/j.matdes.2020.108649 · Cited by 35 · see citing works
Beyene, A. B., Su, W.-N. J., Tsai, H., Tegegne, W. A., Chen, C., Huang, C., Mareš, D., Prajzler, V., Huang, W., & Hwang, B. (2022) · ACS Applied Nano Materials · doi:10.1021/acsanm.2c02571 · Cited by 33 · see citing works
SERS studies on normal epithelial and cancer cells derived from clinical breast cancer specimens
Shen, L., Du, Y., Wei, N., Li, Q., Li, S., Sun, T., Xu, S., Wang, H., Man, X., & Han, B. (2020) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2020.118364 · Cited by 32 · see citing works
Self-citationAkbar, S., Majeed, M. I., Nawaz, H., Rashid, N., Tariq, A., Hameed, W., Shakeel, S., Dastgir, G., Bari, R. Z. A., Iqbal, M., et al. (2021) · Analytical Letters · doi:10.1080/00032719.2021.2017948 · Cited by 31 · see citing works
Luo, P., Sun, X., Li, Y., Li, Y., Shao, W., Zhen, L., & Xu, C. (2021) · ACS Applied Energy Materials · doi:10.1021/acsaem.1c01958 · Cited by 31 · see citing works
Mitigating sarcoplasmic reticulum stress limits disuse-induced muscle loss in hindlimb unloaded mice
Khan, A. A., Gul, M. T., Karim, A., Ranade, A. V., Azeem, M., Ibrahim, Z., Ramachandran, G., Nair, V. A., Ahmad, F., Elmoselhi, A. B., et al. (2022) · npj Microgravity · doi:10.1038/s41526-022-00211-w · Cited by 30 · see citing works
Cross-Linked Elastin-like Polypeptide Membranes as a Model for Medial Arterial Calcification
Gourgas, O., Muiznieks, L. D., Bello, D. G., Nanci, A., Sharpe, S. J., & Cerruti, M. (2019) · Biomacromolecules · doi:10.1021/acs.biomac.9b00417 · Cited by 28 · see citing works
Ning, T., Li, H., Chen, Y., Zhang, B., Zhang, F., & Wang, S. (2021) · Vibrational Spectroscopy · doi:10.1016/j.vibspec.2021.103260 · Cited by 27 · see citing works
Huang, W., Wu, S., Chen, M., Sun, L., Li, Y., Huang, M., Huang, S., Xu, Z., Chen, R., & Zeng, H. (2015) · Journal of Raman Spectroscopy · doi:10.1002/jrs.4684 · Cited by 27 · see citing works
Self-citationAuner, A. W., Kast, R. E., Rabah, R. M., Poulik, J. M., & Klein, M. D. (2012) · Pediatric Surgery International · doi:10.1007/s00383-012-3211-6 · Cited by 25 · see citing works
Song, D., Chen, T., Wang, S., Chen, S., Li, H., Yu, F., Zhang, J., & Zhang, Z. (2019) · The Analyst · doi:10.1039/c9an01524h · Cited by 25 · see citing works
Polarized Raman microscopy imaging: Capabilities and challenges for cancer research
Abramczyk, H., Brożek-Płuska, B., & Kopec, M. (2018) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2018.03.016 · Cited by 24 · see citing works
High pressure Raman study of type‐I collagen
Paschou, A. M., Katsikini, M., Christofilos, D., Arvanitidis, J., & Ves, S. (2018) · FEBS Journal · doi:10.1111/febs.14506 · Cited by 23 · see citing works
Staniszewska‐Slezak, E., Małek, K., & Barańśka, M. (2015) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2015.03.086 · Cited by 23 · see citing works
Design and evaluation of Raman reporters for the Raman-silent region
Plakas, K., Rosch, L. E., Clark, M. D., Adbul-Rashed, S., Shaffer, T. M., Harmsen, S., Gambhir, S. S., & Detty, M. R. (2022) · Nanotheranostics · doi:10.7150/ntno.58965 · Cited by 22 · see citing works
“In order to expand the multiplexing capabilities of these classes of dyes and avoid spectral interferences, we sought to optimize the pyrylium dye structures for performance in the Raman silent region (1750–2750 cm-1) – a spectral window where Raman bands from biological molecules and tissues are minimized [13, 14] as…”
Compact light source for ultrabroadband coherent anti-Stoke Raman scattering (CARS) microscopy
Mikami, H., Shiozawa, M., Shirai, M., & Watanabe, K. (2015) · Optics Express · doi:10.1364/oe.23.002872 · Cited by 22 · see citing works
Line-scan Raman microscopy complements optical coherence tomography for tumor boundary detection
Sudheendran, N., Qi, J., Young, E. D., Lazar, A. J., Lev, D. C., Pollock, R. E., Larin, K. V., & Shih, W. (2014) · Laser Physics Letters · doi:10.1088/1612-2011/11/10/105602 · Cited by 21 · see citing works
Tombolesi, N., Altara, R., da Silva, G. J. J., Tannous, C., Zouein, F. A., Stensløkken, K., Morresi, A., Paolantoni, M., Booz, G. W., Cataliotti, A., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-07390-2 · Cited by 21 · see citing works
Raman spectroscopy: A novel experimental approach to evaluating cisplatin induced tissue damage
Arzu Hanım, Y. A. Y., Önses, M. S., Şahmetlioğlu, E., Ceyhan, A., Pekdemir, S., Önder, G. Ö., Sezer, G., Sarıca, Z. S., & Aydin, F. A. (2019) · Talanta · doi:10.1016/j.talanta.2019.120343 · Cited by 21 · see citing works
Spectroscopic study of the effect of low dose fast neutrons on the hemoglobin structure
Saeed, A., & Abolaban, F. A. (2021) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2021.120082 · Cited by 20 · see citing works
Liu, C., Qi, J., Lü, J., Wang, S., Wu, C., Shih, W., & Larin, K. V. (2014) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.2038508 · Cited by 19 · see citing works
Budiman, A., Wardhana, Y. W., Ainurofiq, A., Nugraha, Y. P., Qaivani, R., Hakim, S. L., & Aulifa, D. L. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s449159 · Cited by 19 · see citing works
Shu, C., Zheng, W., Wang, Z., Yu, C., & Huang, Z. (2021) · Optics Letters · doi:10.1364/ol.438713 · Cited by 19 · see citing works
León-Bejarano, F., Mendez, M. O., Ramírez‐Elías, M. G., & Alba, A. (2019) · Applied Spectroscopy · doi:10.1177/0003702819860121 · Cited by 18 · see citing works
Lee, S., Jue, M., Cho, M., Lee, K.-H., Paulson, B., Jo, H., Song, J. S., Kang, S., & Kim, J. K. (2023) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10529 · Cited by 17 · see citing works
Sun, L., Xu, Z., Huang, W., Wu, S., Lin, X., Zhu, F., Liu, N., Huang, M., Chen, R., & Zeng, H. (2015) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-015-2082-3 · Cited by 16 · see citing works
Self-citationLi, H., Ning, T., Yu, F., Chen, Y., Zhang, B., & Wang, S. (2021) · Molecules · doi:10.3390/molecules26040921 · Cited by 16 · see citing works
Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis
Girard, A., Cooper, A., Mabbott, S. B., Bradley, B., Asiala, S. M., Jamieson, L. E., Clucas, C., Capewell, P., Marchesi, F., Gibbins, M. P., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1010060 · Cited by 15 · see citing works
Signature molecular changes in the skeletal muscle of hindlimb unloaded mice
Azeem, M., Qaisar, R., Karim, A., Ranade, A. V., & Elmoselhi, A. B. (2021) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2021.100930 · Cited by 15 · see citing works
Senger, R. S., Issa, A. S., Agnor, B., Talty, J., Hollis, A., & Robertson, J. L. (2022) · Applied Spectroscopy · doi:10.1177/00037028211061769 · Cited by 15 · see citing works
Walther, A. R., Stepula, E., Ditzel, N., Kassem, M. S., Bergholt, M. S., & Hedegaard, M. A. B. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.2c04743 · Cited by 13 · see citing works
Lipid Metabolites as Potential Regulators of the Antibiotic Resistome in Tetramorium caespitum
Jin, M., Zhang, Q., Xu, N., Zhang, Z., Guo, H., Li, J., Ding, K., Sun, X., Yang, X., Zhu, D., et al. (2024) · Environmental Science & Technology · doi:10.1021/acs.est.3c05741 · Cited by 13 · see citing works
Abramczyk, H., & Brożek-Płuska, B. (2017) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2017.05.142 · Cited by 13 · see citing works
Filho, F. F. D. M., Morillas, H., Derluyn, H., Maguregui, M., & Grégoire, D. (2019) · Microchemical Journal · doi:10.1016/j.microc.2019.02.014 · Cited by 13 · see citing works
Identification of biomarkers on kidney failure by Raman spectroscopy
Gulyamov, S., Shamshiddinova, M., Bae, W., Park, Y. C., Kim, H. J., Cho, W., & Lee, Y. (2021) · Journal of Raman Spectroscopy · doi:10.1002/jrs.6210 · Cited by 13 · see citing works
Raman Spectroscopic Detection and Quantification of Macro- and Microhematuria in Human Urine
Carswell, W. F., Robertson, J. L., & Senger, R. S. (2022) · Applied Spectroscopy · doi:10.1177/00037028211060853 · Cited by 13 · see citing works
Milligan, K., Nest, S. J. V., Deng, X., Ali‐Adeeb, R., Shreeves, P., Punch, S., Costie, N., Pavey, N., Crook, J. M., Berman, D. M., et al. (2022) · Journal of Biophotonics · doi:10.1002/jbio.202200121 · Cited by 13 · see citing works
Kar, S., Jaswandkar, S. V., Katti, K. S., Kang, J. W., So, P. T. C., Paulmurugan, R., Liepmann, D., Renugopalakrishnan, V., & Katti, D. R. (2022) · Scientific Reports · doi:10.1038/s41598-022-11800-w · Cited by 12 · see citing works
Non-enzymatic lab-on-paper devices for biosensing applications
Marques, A. C., Pinheiro, T., Martins, G. V., Cardoso, R., Martins, R., Sales, M. G. F., & Fortunato, E. M. C. (2020) · Comprehensive analytical chemistry · doi:10.1016/bs.coac.2020.05.001 · Cited by 12 · see citing works
Liu, Y., Liu, J.-F., Wan, J., Hao, H., Liu, G., & Huang, X. (2025) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2025.05.051 · Cited by 11 · see citing works
In-vivo spinal nerve sensing in MISS using Raman spectroscopy
Chen, H., Xu, W., & Broderick, N. G. R. (2016) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.2218783 · Cited by 11 · see citing works
Side‐Viewing Endoscopic Raman Spectroscopy for Angle‐Resolved Analysis of Luminal Organs
Jayhooni, S. M. H., Short, M., Assadsangabi, B., Hohert, G., Du, C., Zeng, H., & Takahata, K. (2019) · Advanced Materials Technologies · doi:10.1002/admt.201900364 · Cited by 11 · see citing works
Self-citationRaman spectroscopic and fractal analysis of blood samples of dengue fever patients
Swapna, M. S., Shinker, S. S., Suresh Babu, S., & Sankararaman, S. I. (2018) · Bio-Medical Materials and Engineering · doi:10.3233/bme-181023 · Cited by 11 · see citing works
Kamali, M., Costa, M. E. V., & Capela, I. (2017) · doi:10.1002/9781119407805.ch13 · Cited by 11 · see citing works
Autofluorescence-Raman Spectroscopy for Ex Vivo Mapping Colorectal Liver Metastases and Liver Tissue
Corden, C., Boitor, R., Dusanjh, P., Harwood, A., Mukherjee, A., Gomez, D., & Notingher, I. (2023) · Journal of Surgical Research · doi:10.1016/j.jss.2023.02.014 · Cited by 10 · see citing works
Romo, J. C. M., ROSAS, F. L., Mendoza-González, R., Padilla-Díaz, A., Mora-González, M., & Martínez-Cano, E. (2013) · Spectroscopy Letters · doi:10.1080/00387010.2013.855640 · Cited by 10 · see citing works
Characterization of the Striatal Extracellular Matrix in a Mouse Model of Parkinson’s Disease
Freitas, A., Aroso, M., Barros, A. S., Fernández, M., Conde‐Sousa, E., Leite, M., Carvalho, E. D., Ribeiro, C. C., Ferreira, R. M., Pêgo, A. P., et al. (2021) · Antioxidants · doi:10.3390/antiox10071095 · Cited by 10 · see citing works
Veliz, L., Lambin, C., Cooper, T. T., McCarvell, W. M., Lajoie, G., Postovit, L.-M. M., & Lagugné‐Labarthet, F. (2025) · Nanoscale · doi:10.1039/d4nr04926h · Cited by 9 · see citing works
Implikasi Pola Kerja Telensefalon dan Korteks Cerebral dalam Pendidikan Jasmani
Mustafa, P. S. (2020) · Media Ilmu Keolahragaan Indonesia · doi:10.15294/miki.v10i2.24901 · Cited by 9 · see citing works
Denoising of Raman spectroscopy for biological samples based on empirical mode decomposition
León-Bejarano, F., Ramírez‐Elías, M. G., Méndez, M. O., Dorantes-Méndez, G., Rodríguez‐Aranda, M. C., & Alba, A. (2017) · International Journal of Modern Physics C · doi:10.1142/s0129183117501169 · Cited by 9 · see citing works
Zahn, J., Germond, A., Lundgren, A. Y., & Cicerone, M. T. (2022) · Journal of Biophotonics · doi:10.1002/jbio.202100274 · Cited by 8 · see citing works
Yang, L., Iyer, R. R., Sorrells, J. E., Renteria, C. A., & Boppart, S. A. (2024) · Optics Express · doi:10.1364/oe.517417 · Cited by 8 · see citing works
Lodoso‐Torrecilla, I., Konka, J., Kreuzer, M., Jiménez‐Piqué, E., Español, M., & Ginebra, M. (2024) · Biomaterials Advances · doi:10.1016/j.bioadv.2024.213982 · Cited by 7 · see citing works
Jiao, C., Chen, M., Liao, J., Li, J., Zhang, R., & He, S. (2025) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2025.126182 · Cited by 7 · see citing works
Udensi, J., Loskutova, E., Loughman, J., & Byrne, H. J. (2024) · Journal of Biophotonics · doi:10.1002/jbio.202400060 · Cited by 7 · see citing works
Shin, J., Choi, J. H., Choi, S., Jung, G. B., Park, H., & Moon, S. W. (2014) · Microscopy Research and Technique · doi:10.1002/jemt.22431 · Cited by 7 · see citing works
In vivo Raman spectroscopic characterization of papillary thyroid carcinoma
Neto, L. P. M., Soto, C. A. T., Chagas, M. J., Carvalho, L. F. C. S., Rajasekaran, R., & Martin, A. A. (2018) · Vibrational Spectroscopy · doi:10.1016/j.vibspec.2018.12.008 · Cited by 7 · see citing works
Ondieki, A. M., Birech, Z., Kaduki, K. A., Mwangi, P. W., Juma, M. W., & Chege, B. M. (2023) · Vibrational Spectroscopy · doi:10.1016/j.vibspec.2023.103605 · Cited by 7 · see citing works
Assadsangabi, B., Jayhooni, S. M. H., Short, M., Zeng, H., & Takahata, K. (2019) · Smart Materials and Structures · doi:10.1088/1361-665x/ab36a0 · Cited by 7 · see citing works
Self-citationLiu, J., Wu, Z., Lu, Y., Ren, D., Chu, J., Zeng, H., & Wang, S. (2024) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2024.113039 · Cited by 6 · see citing works
Self-citationPatro, B. D. K., & Suvin, P. S. (2025) · Tribology International · doi:10.1016/j.triboint.2025.110957 · Cited by 6 · see citing works
Ex vivo Raman spectroscopic study of breast metastatic lesions in lungs in animal models
Bhattacharjee, T., Tawde, S., Hudlikar, R. R., Mahimkar, M. B., Maru, G. B., Ingle, A., & Krishna, C. M. (2015) · Journal of Biomedical Optics · doi:10.1117/1.jbo.20.8.085006 · Cited by 6 · see citing works
Li, H., Ren, Y. T., Yu, F., Song, D., Zhu, L., Yu, S., Jiang, S., & Wang, S. (2021) · Journal of Spectroscopy · doi:10.1155/2021/5572782 · Cited by 6 · see citing works
Mansano, E. S. B., de Morais, G. R., Moratto, E. M., Sato, F., Neto, A. M., Svidzinski, T. I. E., Baesso, M. L., & Hernandes, L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106256 · Cited by 6 · see citing works
Mansano, E. S. B., de Morais, G. R., Moratto, E. M., Sato, F., Baesso, M. L., Medina, A. N., Svidzinski, T. I. E., & Hernandes, L. (2017) · Photochemistry and Photobiology · doi:10.1111/php.12840 · Cited by 6 · see citing works
Spectrally Silent and Optically Transparent: Clear-SiR for Deep Raman Biomolecular Sensing
Lee, M. K. H., Mizushima, K., Zheng, P., Tanwar, S., Gupta, A., Fujita, K., & Barman, I. (2025) · ACS Sensors · doi:10.1021/acssensors.5c02046 · Cited by 5 · see citing works
Vivcharenko, V., Trzaskowska, M., Gieroba, B., Pałka, K., Sroka‐Bartnicka, A., & Przekora, A. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.148068 · Cited by 5 · see citing works
de Melo, I. S., de Medeiros, N. C., Ferro, J. N. D. S., Cavalcante-Araújo, P. M., de Oliveira, T. L., Santos, C. E. A., Cardoso-Sousa, L., Aguiar, E. M. G., Oliveira, S. W., de Castro, O. W., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0229761 · Cited by 5 · see citing works
Alix, J. J. P., Plesia, M., Lloyd, G. R., Dudgeon, A. P., Kendall, C. A., McDermott, C. J., Gorman, G. S., Taylor, R. W., Shaw, P. J., & Day, J. C. C. (2021) · Journal of Raman Spectroscopy · doi:10.1002/jrs.6273 · Cited by 5 · see citing works
Zhao, J., Lui, H., McLean, D. I., & Zeng, H. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802838-4.00012-1 · Cited by 5 · see citing works
Self-citationRaman Spectroscopy of Pharmaceutical Cocrystals in Nanosized Pores of Mesoporous Silica
Ohta, R., Ueno, Y., & Ajito, K. (2017) · Analytical Sciences · doi:10.2116/analsci.33.47 · Cited by 5 · see citing works
Rist, B. L., Witte, S. A., & Schultz, Z. D. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c02685 · Cited by 4 · see citing works
Jebakumari, K. A. E., Murugasenapathi, N. K., Udit Millenn, R., El-Kemary, M. A., & Palanisamy, T. (2024) · Analytical Letters · doi:10.1080/00032719.2024.2322028 · Cited by 4 · see citing works
Malignant Tissue Optical Properties
Bashkatov, A. N., Zakharov, V. P., Bucharskaya, A. B., Borisova, E. G., Khristoforova, Y. А., Genina, E. A., & Tuchin, V. V. (2020) · Springer eBooks · doi:10.1007/978-3-030-44594-2_1 · Cited by 4 · see citing works
He, W., Wang, M., Li, M., Zhong, Z., Chen, H., Xi, S., Luan, Z., Li, C., & Zhang, X. (2022) · Frontiers in Marine Science · doi:10.3389/fmars.2022.1077595 · Cited by 4 · see citing works
- Authors
- Huang, N., Short, M., Zhao, J., Wang, H., Lui, H., Korbelik, M., & Zeng, H.
- Affiliations
- BC Cancer Agency (CA)
- Venue
- Optics Express
- Publisher
- Optica Publishing Group
- Published
- 2011-10-27
- Volume
- 19
- Issue
- 23
- Pages
- 22892
- ISSN
- 1094-4087 (ISSN-L)
- OpenAlex
- W2040773107
- Cited by
- 131
- References
- 51
- Citations by year
- 2026: 2 · 2025: 11 · 2024: 12 · 2023: 10 · 2022: 14 · 2021: 22 · 2020: 9 · 2019: 10 · 2018: 9 · 2017: 6 · 2016: 6 · 2015: 8 · 2014: 8 · 2013: 2 · 2012: 2
- FWCI
- 2.20
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Optics Express (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Dermatology Foundation
- Canadian Dermatology Foundation
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
- Physical Sciences › Materials Science › Electronic, Optical and Magnetic Materials › Gold and Silver Nanoparticles Synthesis and Applications
- Keywords
- Raman spectra, mouse organs, autofluorescence, tissue characterization
- MeSH terms
- Animals, Fluorescence, Mice, Inbred C3H, Organ Specificity, Spectrum Analysis, Raman, Models, Animal, Serum, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
