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Turbulent nature of refractive-index variations in biological tissue
Abstract
Phase-contrast microscopy shows that the structure of the refractive-index inhomogeneities in a variety of mammalian tissues resembles that of frozen turbulence. Viewed over a range of scales, the spectrum of index variations exhibits a power-law behavior for spatial frequencies spanning at least a decade (0.5-5 microm(-1)) and has an outer scale in the range of 4-10 microm, above which correlations are no longer seen. The observed structure function fits the classical Kolmogorov model of turbulence. These observations are fundamental to understanding light propagation in tissue and may provide clues about how tissues develop and organize.
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Cited by
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Vogel, A., & Venugopalan, V. (2003) · Chemical Reviews · doi:10.1021/cr010379n · Cited by 1,918
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Chan, W. L., Deibel, J., & Mittleman, D. M. (2007) · Reports on Progress in Physics · doi:10.1088/0034-4885/70/8/r02 · Cited by 965
Speckle in Optical Coherence Tomography
Schmitt, J. M., Xiang, S. H., & Yung, K. M. (1999) · Journal of Biomedical Optics · doi:10.1117/1.429925 · Cited by 837
Self-citationRare-earth-doped biological composites as in vivo shortwave infrared reporters
Naczynski, D. J., Tan, M. C., Zevon, M., Wall, B., Kohl, J., Kulesa, A., Chen, S., Roth, C. M., Riman, R. E., & Moghe, P. V. (2013) · Nature Communications · doi:10.1038/ncomms3199 · Cited by 759
Metadata
- Authors
- Schmitt, J. M., & Kumar, G.
- Venue
- Optics Letters
- Publisher
- Optica Publishing Group
- Published
- 1996-08-15
- Volume
- 21
- Issue
- 16
- Pages
- 1310
- ISSN
- 0146-9592 (ISSN-L)
- 1539-4794
- OpenAlex
- W2091590472
- Cited by
- 343
- References
- 0
- FWCI
- 2.40
- Type
- journal article
- Language
- en
- Open access
- closed
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- Schmitt, J. M., & Kumar, G. (1996). Turbulent nature of refractive-index variations in biological tissue. Optics Letters. https://doi.org/10.1364/ol.21.001310
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