The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
High-sensitivity vibrational imaging with frequency modulation coherent anti-Stokes Raman scattering (FM CARS) microscopy
Abstract
We demonstrate a new approach to coherent anti-Stokes Raman scattering (CARS) microscopy that significantly increases the detection sensitivity. CARS signals are generated by collinearly overlapped, tightly focused, and raster scanned pump and Stokes laser beams, whose difference frequency is rapidly modulated. The resulting amplitude modulation of the CARS signal is detected through a lock-in amplifier. This scheme efficiently suppresses the nonresonant background and allows for the detection of far fewer vibrational oscillators than possible through existing CARS microscopy methods.
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Citations
Cites
Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy
Evans, C. L., Potma, E. O., Puoris'haag, M., Côté, D., Lin, C. P., & Xie, X. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508282102 · Cited by 957
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Cited by
Raman Techniques: Fundamentals and Frontiers
Jones, R. R., Hooper, D. C., Zhang, L., Wolverson, D., & Valev, V. K. (2019) · Nanoscale Research Letters · doi:10.1186/s11671-019-3039-2 · Cited by 804
Raman spectroscopy: techniques and applications in the life sciences
Shipp, D. W., Sinjab, F., & Notingher, I. (2017) · Advances in Optics and Photonics · doi:10.1364/aop.9.000315 · Cited by 396
Femtosecond stimulated Raman microscopy
Ploetz, E., Laimgruber, S., Berner, S., Zinth, W., & Gilch, P. (2007) · Applied Physics B · doi:10.1007/s00340-007-2630-x · Cited by 324
Raman and CARS microspectroscopy of cells and tissues
Krafft, C., Dietzek, B., & Popp, J. (2009) · The Analyst · doi:10.1039/b822354h · Cited by 271
Label‐Free Live‐Cell Imaging of Nucleic Acids Using Stimulated Raman Scattering Microscopy
Zhang, X., Roeffaers, M. B. J., Basu, S., Daniele, J. R., Fu, D., Freudiger, C. W., Holtom, G. R., & Xie, X. S. (2012) · ChemPhysChem · doi:10.1002/cphc.201100890 · Cited by 171
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Metadata
- Authors
- Ganikhanov, F., Evans, C. L., Saar, B. G., & Xie, X. S.
- Venue
- Optics Letters
- Publisher
- Optica Publishing Group
- Published
- 2006-06-15
- Volume
- 31
- Issue
- 12
- Pages
- 1872
- ISSN
- 0146-9592 (ISSN-L)
- 1539-4794
- OpenAlex
- W1996580214
- Cited by
- 236
- References
- 1
- FWCI
- 8.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ganikhanov, F., Evans, C. L., Saar, B. G., & Xie, X. S. (2006). High-sensitivity vibrational imaging with frequency modulation coherent anti-Stokes Raman scattering (FM CARS) microscopy. Optics Letters. https://doi.org/10.1364/ol.31.001872
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